检索结果 - Luca Laraia

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  1. 1
    Unifying principles for the design and evaluation of natural product-inspired compound collections

    Unifying principles for the design and evaluation of natural product-inspired compound collections 由 Frederik Simonsen Bro, Luca Laraia

    出版 2025
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  2. 2
    Small-Molecule Inhibitors of Reactive Oxygen Species Production

    Small-Molecule Inhibitors of Reactive Oxygen Species Production 由 Elisa Sassetti, Mads H. Clausen, Luca Laraia

    出版 2021
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  3. 3
    Pseudo Natural Products—Chemical Evolution of Natural Product Structure

    Pseudo Natural Products—Chemical Evolution of Natural Product Structure 由 George Karageorgis, Daniel J. Foley, Luca Laraia, Susanne Brakmann, Herbert Waldmann

    出版 2021
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  4. 4
    Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

    Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions 由 Luca Laraia, Grahame J. McKenzie, David R. Spring, Ashok R. Venkitaraman, David J. Huggins

    出版 2015
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  5. 5
    Discovery of Novel Cinchona‐Alkaloid‐Inspired Oxazatwistane Autophagy Inhibitors

    Discovery of Novel Cinchona‐Alkaloid‐Inspired Oxazatwistane Autophagy Inhibitors 由 Luca Laraia, Kosuke Ohsawa, Georgios Konstantinidis, Lucas Robke, Yao‐Wen Wu, Kamal Kumar, Herbert Waldmann

    出版 2017
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    Artigo
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  6. 6
    Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

    Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor 由 Daniel J. Foley, Sarah Zinken, Dale Corkery, Luca Laraia, Axel Pahl, Yao‐Wen Wu, Herbert Waldmann

    出版 2020
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  7. 7
    Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin

    Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin 由 Marjorie A. Carnero Corrales, Sarah Zinken, Georgios Konstantinidis, Muhammad Rafehi, Aliaa Abdelrahman, Yao‐Wen Wu, Petra Janning, Christa E. Müller, Luca Laraia, Herbert Waldmann

    出版 2021
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    Artigo
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  8. 8
    Identification of a Privileged Scaffold for Inhibition of Sterol Transport Proteins through the Synthesis and Ring Distortion of Diverse, Pseudo-Natural Products

    Identification of a Privileged Scaffold for Inhibition of Sterol Transport Proteins through the Synthesis and Ring Distortion of Diverse, Pseudo-Natural Products 由 Frederik Simonsen Bro, Laura Depta, Nienke J Dekker, Hogan P. Bryce-Rogers, M. M. Madsen, Kaia Fiil Præstegaard, Tino Petersson, Thomas Whitmarsh‐Everiss, Mariusz Kubus, Luca Laraia

    出版 2025
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  9. 9
    Diversity-oriented synthesis as a tool for identifying new modulators of mitosis

    Diversity-oriented synthesis as a tool for identifying new modulators of mitosis 由 Brett M. Ibbeson, Luca Laraia, Esther Alza, Cornelius J. O’ Connor, Yaw Sing Tan, Huw M. L. Davies, Grahame J. McKenzie, Ashok R. Venkitaraman, David R. Spring

    出版 2014
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  10. 10
    Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34

    Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34 由 Lucas Robke, Luca Laraia, Marjorie A. Carnero Corrales, Georgios Konstantinidis, Makoto Muroi, André Richters, Michael Winzker, Tobias Engbring, Stefano Tomassi, Nobumoto Watanabe, Hiroyuki Osada, Daniel Rauh, Herbert Waldmann, Yao‐Wen Wu, Julian Engel

    出版 2017
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  11. 11
    Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

    Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor 由 Luca Laraia, Guillaume Garivet, Daniel J. Foley, Nadine Kaiser, Sebastian Müller, Sarah Zinken, Thomas Pinkert, Julian Wilke, Dale Corkery, Axel Pahl, Sonja Sievers, Petra Janning, Christoph Arenz, Yao‐Wen Wu, Raphaël Rodriguez, Herbert Waldmann

    出版 2019
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  12. 12
    Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP

    Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP 由 Marko Cigler, Hana Imrichová, Fabian Frommelt, Lucie Caramelle, Laura Depta, Andrea Rukavina, Chrysanthi Kagiou, J. Thomas Hannich, Cristina Mayor‐Ruiz, Giulio Superti‐Furga, Sonja Sievers, Alison Forrester, Luca Laraia, Herbert Waldmann, Georg E. Winter

    出版 2024
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    Artigo
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  13. 13
    Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3

    Synthesis of Indomorphan Pseudo‐Natural Product Inhibitors of Glucose Transporters GLUT‐1 and ‐3 由 Javier Ceballos, Melanie Schwalfenberg, George Karageorgis, Elena S. Reckzeh, Sonja Sievers, Claude Ostermann, Axel Pahl, Magnus Sellstedt, Jessica Nowacki, Marjorie A. Carnero Corrales, Julian Wilke, Luca Laraia, Kirsten Tschapalda, Malte Metz, Dominik A. Sehr, Silke Brand, Konstanze F. Winklhofer, Petra Janning, Slava Ziegler, Herbert Waldmann

    出版 2019
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