Torthaí cuardaigh - Lian‐Sheng Li

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  1. 1
    Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

    Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism de réir Piro Lito, Martha Solomon, Lian‐Sheng Li, Rasmus Hansen, Neal Rosen

    Foilsithe / Cruthaithe 2016
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  2. 2
    The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus

    The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus de réir Ying Zhang, Chao Liu, Bingbing Wu, Lian‐Sheng Li, Wei Li, Li Yuan

    Foilsithe / Cruthaithe 2021
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  3. 3
    Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

    Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer de réir Mı́riam Molina-Arcas, Christopher Moore, Sareena Rana, Febe van Maldegem, Edurne Mugarza, Pablo Romero-Clavijo, Eleanor Herbert, Stuart Horswell, Lian‐Sheng Li, Matthew R. Janes, David C. Hancock, Julian Downward

    Foilsithe / Cruthaithe 2019
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  4. 4
    Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia

    Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia de réir Matthew R. Janes, Collin Vu, Sharmila Mallya, Marie P. Shieh, Jose J. Limon, Lian‐Sheng Li, Katti Jessen, Michael Martin, Pingda Ren, Michael B. Lilly, Leonard S. Sender, Yi Liu, Christian Rommel, David A. Fruman

    Foilsithe / Cruthaithe 2012
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  5. 5
    Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

    Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State de réir Matthew P. Patricelli, Matthew R. Janes, Lian‐Sheng Li, Rasmus Hansen, Ulf Peters, Linda Kessler, Yuching Chen, Jeff Kucharski, Jun Feng, Tess Ely, Jeffrey H. Chen, Sarah J. Firdaus, Anjali Babbar, Pingda Ren, Yi Liu

    Foilsithe / Cruthaithe 2016
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  6. 6
    Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function*

    Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function* de réir Lomon So, Sung Su Yea, Jean Oak, Mengrou Lu, Arun Manmadhan, Qiao Han Ke, Matthew R. Janes, Linda Kessler, Jeff Kucharski, Lian‐Sheng Li, Michael Martin, Pingda Ren, Katti Jessen, Yi Liu, Christian Rommel, David A. Fruman

    Foilsithe / Cruthaithe 2012
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  7. 7
    KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition

    KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition de réir Sandra Misale, Jackson P. Fatherree, Eliane Cortez, Chendi Li, Samantha Bilton, Daria Timonina, David T. Myers, Dana Lee, María Gomez‐Caraballo, Max Greenberg, Varuna Nangia, Patricia Greninger, Regina K. Egan, Joseph McClanaghan, Giovanna T. Stein, Ellen Murchie, Patrick P. Zarrinkar, Matthew R. Janes, Lian‐Sheng Li, Yi Liu, Aaron N. Hata, Cyril H. Benes

    Foilsithe / Cruthaithe 2018
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  8. 8
    PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models

    PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models de réir David G. Winkler, L. Kerrie, Jonathan P. DiNitto, Janid A. Ali, Kerry White, Erin Brophy, Melissa Pink, Jennifer Proctor, Jennifer Lussier, Christian M. Martin, Jennifer Hoyt, Bonnie Tillotson, Erin L. Murphy, Alice R. Lim, Brian D. Thomas, John R. MacDougall, Pingda Ren, Yi Liu, Lian‐Sheng Li, Katti Jessen, Christian Fritz, Joi Dunbar, James R. Porter, Christian Rommel, Vito J. Palombella, Paul S. Changelian, Jeffery L. Kutok

    Foilsithe / Cruthaithe 2013
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  9. 9
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor de réir Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li, Rasmus Hansen, Ulf Peters, Xin Guo, Yuching Chen, Anjali Babbar, Sarah J. Firdaus, Levan Darjania, Jun Feng, Jeffrey H. Chen, Shuangwei Li, Shisheng Li, Yun Oliver Long, Carol Thach, Yuan Liu, Ata Zarieh, Tess Ely, Jeff Kucharski, Linda Kessler, Tao Wu, Ke Yu, Yi Wang, Yvonne Yao, Xiaohu Deng, Patrick P. Zarrinkar, Dirk Brehmer, Dashyant Dhanak, Matthew V. Lorenzi, Dana D. Hu‐Lowe, Matthew P. Patricelli, Pingda Ren, Yi Liu

    Foilsithe / Cruthaithe 2018
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  10. 10
    Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

    Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia de réir Szymon Kłossowski, Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, EunGi Kim, Brian M. Linhares, Dong Chen, Gloria Jih, Eric Perkey, Huang Huang, Miao He, Bo Wen, Yì Wáng, Ke Yu, Stanley Chun-Wei Lee, Gwenn Danet-Desnoyers, Winifred Trotman, Malathi Kandarpa, Anitria Cotton, Omar Abdel‐Wahab, Hongwei Lei, Yali Dou, Mónica L. Guzmán, Luke F. Peterson, Tanja A. Grüber, Sarah M. Choi, Duxin Sun, Pingda Ren, Lian‐Sheng Li, Yi Liu, Francis Burrows, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka

    Foilsithe / Cruthaithe 2019
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