检索结果 - Levon Halabelian

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  1. 1
    Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

    Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition 由 Levon Halabelian, Mani Ravichandran, Yanjun Li, Hong Zeng, Anjana Rao, L. Aravind, C.H. Arrowsmith

    出版 2019
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  2. 2
    HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

    HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells 由 Vipul Shukla, Levon Halabelian, Sanjana Balagere, Daniela Samaniego‐Castruita, Douglas E. Feldman, C.H. Arrowsmith, Anjana Rao, L. Aravind

    出版 2019
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  3. 3
    The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition

    The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition 由 Serah Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, C.H. Arrowsmith, Dalia Baršytė-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian

    出版 2023
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  4. 4
    Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation

    Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation 由 Bryan J. Fraser, Serap Beldar, Almagul Seitova, Ashley Hutchinson, Dhiraj Mannar, Yanjun Li, Daniel Kwon, Ruiyan Tan, Ryan P. Wilson, Karoline Leopold, Sriram Subramaniam, Levon Halabelian, C.H. Arrowsmith, François Bénard

    出版 2022
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  5. 5
    Identification of lysine isobutyrylation as a new histone modification mark

    Identification of lysine isobutyrylation as a new histone modification mark 由 Zhesi Zhu, Zhen Han, Levon Halabelian, Xiangkun Yang, Jun Ding, Nawei Zhang, Liza Ngo, Jiabao Song, Hong Zeng, Maomao He, Yingming Zhao, C.H. Arrowsmith, Minkui Luo, Michael G. Bartlett, Y. George Zheng

    出版 2020
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  6. 6
    The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

    The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates 由 Magnus E. Jakobsson, Jędrzej Małecki, Levon Halabelian, Benedikt S. Nilges, Rita Pinto, Srikanth Kudithipudi, Stephanie Munk, Erna Davydova, Fawzi Rahmadiyan Zuhairi, C.H. Arrowsmith, Albert Jeltsch, Sebastian A. Leidel, Jesper V. Olsen, Pål Ø. Falnes

    出版 2018
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  7. 7
    Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

    Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2 由 Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, Sun‐Joo Kim, Jun Ding, Maomao He, Levon Halabelian, Lu Yang, Prabakaran Nagarajan, Mark R. Parthun, Sangkyu Lee, Saadi Khochbin, Y. George Zheng, Yingming Zhao

    出版 2021
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  8. 8
    An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

    An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity 由 M. Bose, Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu, Kacey Talbot, Mohammad Anwar Hossain, Peter J. Brown, Scott Houliston, Julia Garcia Perez, Fengling Li, Meareg Amare, Peter Halfmann, Jessica R. Smith, Alec J. Hirsch, C.H. Arrowsmith, Levon Halabelian, Ava M. Vargason, Rafael M. Couñago, Jamie J. Arnold, Craig E. Cameron, Nathaniel J. Moorman, Mark T. Heise, Timothy M. Willson

    出版 2025
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  9. 9
    Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

    Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells 由 Mélanie Uguen, Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk, Ka Yang, Yani Zhao, Michael A. Stashko, Jacqueline L. Norris‐Drouin, Jarod M. Waybright, Serap Beldar, Justin M. Rectenwald, Angie L. Mordant, Thomas S. Webb, Laura E. Herring, C.H. Arrowsmith, Suzanne Ackloo, Steven P. Gygi, Robert K. McGinty, Dalia Baršytė-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I. James, Kenneth H. Pearce, Stephen V. Frye

    出版 2025
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  10. 10
    Discovery of a chemical probe for PRDM9

    Discovery of a chemical probe for PRDM9 由 Abdellah Allali‐Hassani, Magdalena M. Szewczyk, Danton Ivanochko, Shawna Organ, Jabez Bok, Jessica Ho, Florence Gay, Fengling Li, Levi L. Blazer, Mohammad S. Eram, Levon Halabelian, David Dilworth, Genna M. Luciani, Evelyne Lima‐Fernandes, Qin Wu, P. Loppnau, Nathan Palmer, S. Zakiah A. Talib, Peter J. Brown, Matthieu Schapira, Philipp Kaldis, Rónán C. O’Hagan, Ernesto Guccione, Dalia Baršytė-Lovejoy, C.H. Arrowsmith, John M. Sanders, Solomon D. Kattar, David Jonathan Bennett, Benjamin Nicholson, Masoud Vedadi

    出版 2019
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  11. 11
    Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

    Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response 由 Magdalena M. Szewczyk, Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian, Suzanne Ackloo, Amber L. Couzens, Mohammad S. Eram, David Dilworth, Hideto Fukushi, Rachel Harding, Carlo C. dela Seña, Tsukasa Sugo, Kôzô Hayashi, David McLeod, Carlos Zepeda, Ahmed Aman, María Sánchez‐Osuna, Éric Bonneil, Shinji Takagi, Rima Al‐awar, Mike Tyers, Stéphane Richard, Masayuki Takizawa, Anne‐Claude Gingras, C.H. Arrowsmith, Masoud Vedadi, Peter J. Brown, Hiroshi Nara, Dalia Baršytė-Lovejoy

    出版 2020
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  12. 12
    Discovery of Nanomolar DCAF1 Small Molecule Ligands

    Discovery of Nanomolar DCAF1 Small Molecule Ligands 由 Alice Shi Ming Li, Serah Kimani, Brian J. Wilson, Mahmoud Noureldin, Héctor González-Álvarez, Ahmed Mamai, Laurent Hoffer, John P. Guilinger, Ying Zhang, Moritz von Rechenberg, Jeremy S. Disch, Christopher J. Mulhern, Belinda L. Slakman, John W. Cuozzo, Aiping Dong, Gennady Poda, Mohammed Mohammed, Punit Saraon, Manish Mittal, Pratik Modh, V. Rathod, Bhashant Patel, Suzanne Ackloo, Vijayaratnam Santhakumar, Magdalena M. Szewczyk, Dalia Baršytė-Lovejoy, C.H. Arrowsmith, Richard Marcellus, Marie-Aude Guié, Anthony D. Keefe, Peter J. Brown, Levon Halabelian, Rima Al‐awar, Masoud Vedadi

    出版 2023
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  13. 13
    Identification of Direct-acting nsP2 Helicase Inhibitors with Anti-alphaviral Activity

    Identification of Direct-acting nsP2 Helicase Inhibitors with Anti-alphaviral Activity 由 M. Bose, John D. Sears, Kacey Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain, Zachary W. Davis‐Gilbert, Chunqing Zhao, Hans J. Oh, Peter J. Brown, Marcia K. Sanders, Stella R. Moorman, Divakar Ojha, Jane Burdick, Isabella Law, Noah L. Morales, Sabian A. Martinez, P. Loppnau, Julia Garcia Perez, Adam M. Drobish, Thomas E. Morrison, Zachary J. Streblow, Daniel N. Streblow, C.H. Arrowsmith, Ava M. Vargason, Rafael M. Couñago, Levon Halabelian, Jamie J. Arnold, Craig E. Cameron, Nathaniel J. Moorman, Mark T. Heise, Timothy M. Willson

    出版 2025
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  14. 14
    CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

    CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein 由 Fengling Li, Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck, Jan Beránek, Francois Berenger, Albina Bolotokova, Guillaume Bret, Marko Breznik, Emanuele Carosati, Irene Chau, Yu Chen, Artem Cherkasov, Dennis Della Corte, Katrin Denzinger, A. Dong, Sorin Draga, Ian Dunn, Kristina Edfeldt, A.M. Edwards, Merveille Eguida, Paul Eisenhuth, Lukas Friedrich, Alexander Fürll, Spencer Gardiner, Francesco Gentile, Pegah Ghiabi, Elisa Gibson, Marta Glavatskikh, Christoph Gorgulla, Judith Günther, Anders Gunnarsson, Filipp Gusev, Evgeny Gutkin, Levon Halabelian, Rachel Harding, Alexander Hillisch, Laurent Hoffer, Anders Hogner, Scott Houliston, John J. Irwin, Olexandr Isayev, Aleksandra Ivanová, Célien Jacquemard, Austin J. Jarrett, Jan H. Jensen, Dmitri Kireev, Julian M. Kleber, S. Benjamin Koby, David Ryan Koes, Ashutosh Kumar, Maria Kurnikova, Alina Kutlushina, Uta Lessel, Fabian Ließmann, Sijie Liu, Wei Lu, Jens Meiler, Akhila Mettu, Guzel Minibaeva, Rocco Moretti, Connor J. Morris, Chamali Narangoda, Theresa Noonan, Leon Obendorf, Szymon Pach, Amit Pandit, Sumera Perveen, Gennady Poda, Pavel Polishchuk, Kristina Puls, Vera Pütter, Didier Rognan, Dylan Roskams-Edris, Christina Schindler, François Sindt, Vojtěch Spiwok, Casper Steinmann, Rick Stevens, Valerij Talagayev, Damon Tingey, Oanh Vu, W. Patrick Walters, Xiaowen Wang, Zhenyu Wang, Gerhard Wolber, Clemens Alexander Wolf, Lars Wortmann, Hong Zeng, Carlos Zepeda, Kam Y. J. Zhang, Jixian Zhang, Shuangjia Zheng, Matthieu Schapira

    出版 2024
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