检索结果 - Leslie M. Thompson

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  1. 1
    Drosophila in the Study of Neurodegenerative Disease

    Drosophila in the Study of Neurodegenerative Disease 由 J. Lawrence Marsh, Leslie M. Thompson

    出版 2006
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  2. 2
    Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase

    Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase 由 Lee McAlister-Henn, Leslie M. Thompson

    出版 1987
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  3. 3
    Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease

    Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease 由 Joshua Crapser, Joseph Ochaba, Neelakshi Soni, Jack C. Reidling, Leslie M. Thompson, Kim N. Green

    出版 2019
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  4. 4
    Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons

    Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons 由 Christopher Sinadinos, T. Burbidge-King, Daniel Soh, Leslie M. Thompson, J. Lawrence Marsh, Andreas Wyttenbach, Amritpal Mudher

    出版 2009
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  5. 5
    Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

    Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease 由 Judit Pallos, László Bodai, Tamás Lukácsovich, Judith Purcell, Joan S. Steffan, Leslie M. Thompson, J. Lawrence Marsh

    出版 2008
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  6. 6
    Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins

    Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins 由 Natalia Slepko, Arkka Bhattacharyya, George R. Jackson, Joan S. Steffan, J. Lawrence Marsh, Leslie M. Thompson, Ronald Wetzel

    出版 2006
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  7. 7
    Suppression of Huntington's disease pathology in <i>Drosophila</i> by human single-chain Fv antibodies

    Suppression of Huntington's disease pathology in <i>Drosophila</i> by human single-chain Fv antibodies 由 William J. Wolfgang, Todd W. Miller, Jack M. Webster, James S. Huston, Leslie M. Thompson, J. Lawrence Marsh, Anne Messer

    出版 2005
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  8. 8
    Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

    Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau 由 Kim N. Green, Joan S. Steffan, Hilda Martínez‐Coria, Xuemin Sun, Steven S. Schreiber, Leslie M. Thompson, Frank M. LaFerla

    出版 2008
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  9. 9
    Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes

    Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes 由 John H. Lee, Luis Tecedor, Yong Hong Chen, Alex Mas Monteys, Matthew J. Sowada, Leslie M. Thompson, Beverly L. Davidson

    出版 2014
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  10. 10
    A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

    A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor 由 S Pollitt, Judit Pallos, Jieya Shao, Urvee A. Desai, Aye Aye K., Leslie M. Thompson, J. Lawrence Marsh, Marc I. Diamond

    出版 2003
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  11. 11
    Biologically active molecules that reduce polyglutamine aggregation and toxicity

    Biologically active molecules that reduce polyglutamine aggregation and toxicity 由 Urvee A. Desai, Judit Pallos, Aye Aye K., Brent R. Stockwell, Leslie M. Thompson, J. Lawrence Marsh, Marc I. Diamond

    出版 2006
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  12. 12
    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo

    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo 由 Joseph Ochaba, Alex Mas Monteys, Jacqueline G. O’Rourke, Jack C. Reidling, Joan S. Steffan, Beverly L. Davidson, Leslie M. Thompson

    出版 2016
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  13. 13
    Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia

    Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia 由 William R. Wilcox, Patricia L. Tavormina, Deborah Krakow, Hiroshi Kitoh, Ralph S. Lachman, John J. Wasmuth, Leslie M. Thompson, David L. Rimoin

    出版 1998
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  14. 14
    Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo

    Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo 由 Justin Legleiter, Emily J Mitchell, Gregor P. Lotz, Ellen Sapp, Che-Ping Ng, Marian DiFiglia, Leslie M. Thompson, Paul J. Muchowski

    出版 2010
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  15. 15
    Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

    Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins 由 Gianna Fote, Nicolette R. Geller, Nikolaos E. Efstathiou, Nathan G. Hendricks, Demetrios G. Vavvas, Jack C. Reidling, Leslie M. Thompson, Joan S. Steffan

    出版 2022
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  16. 16
    Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i>

    Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i> 由 Namita Agrawal, Judit Pallos, Natalia Slepko, Barbara L. Apostol, László Bodai, Ling-Wen Chang, Ann‐Shyn Chiang, Leslie M. Thompson, J. Lawrence Marsh

    出版 2005
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  17. 17
    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice 由 Xiaofeng Gu, Erin R. Greiner, Rakesh K. Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S. Steffan, Leslie M. Thompson, Ronald Wetzel, X. William Yang

    出版 2009
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  18. 18
    Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle

    Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle 由 Gregor P. Lotz, Justin Legleiter, Rebecca Aron, Emily J Mitchell, Shao-Yi Huang, Che-Ping Ng, Charles Glabe, Leslie M. Thompson, Paul J. Muchowski

    出版 2010
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  19. 19
    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's diseas... 由 Kuan-Yu Liu, Yu‐Chiau Shyu, Brett A. Barbaro, Yuan-Ta Lin, Yijuang Chern, Leslie M. Thompson, Che-Kun James Shen, J. Lawrence Marsh

    出版 2014
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  20. 20
    The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

    The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription 由 Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković, Marilee Greenwald, Yazhen Zhu, Heike Göhler, Erich E. Wanker, Gillian P. Bates, David E. Housman, Leslie M. Thompson

    出版 2000
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