Search Results - Leslie M. Thompson

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  1. 1
    Drosophila in the Study of Neurodegenerative Disease

    Drosophila in the Study of Neurodegenerative Disease by J. Lawrence Marsh, Leslie M. Thompson

    Published 2006
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  2. 2
    Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase

    Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase by Lee McAlister-Henn, Leslie M. Thompson

    Published 1987
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  3. 3
    Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease

    Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease by Joshua Crapser, Joseph Ochaba, Neelakshi Soni, Jack C. Reidling, Leslie M. Thompson, Kim N. Green

    Published 2019
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  4. 4
    Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons

    Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons by Christopher Sinadinos, T. Burbidge-King, Daniel Soh, Leslie M. Thompson, J. Lawrence Marsh, Andreas Wyttenbach, Amritpal Mudher

    Published 2009
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  5. 5
    Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

    Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease by Judit Pallos, László Bodai, Tamás Lukácsovich, Judith Purcell, Joan S. Steffan, Leslie M. Thompson, J. Lawrence Marsh

    Published 2008
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  6. 6
    Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins

    Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins by Natalia Slepko, Arkka Bhattacharyya, George R. Jackson, Joan S. Steffan, J. Lawrence Marsh, Leslie M. Thompson, Ronald Wetzel

    Published 2006
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  7. 7
    Suppression of Huntington's disease pathology in <i>Drosophila</i> by human single-chain Fv antibodies

    Suppression of Huntington's disease pathology in <i>Drosophila</i> by human single-chain Fv antibodies by William J. Wolfgang, Todd W. Miller, Jack M. Webster, James S. Huston, Leslie M. Thompson, J. Lawrence Marsh, Anne Messer

    Published 2005
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  8. 8
    Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau

    Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau by Kim N. Green, Joan S. Steffan, Hilda Martínez‐Coria, Xuemin Sun, Steven S. Schreiber, Leslie M. Thompson, Frank M. LaFerla

    Published 2008
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  9. 9
    Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes

    Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes by John H. Lee, Luis Tecedor, Yong Hong Chen, Alex Mas Monteys, Matthew J. Sowada, Leslie M. Thompson, Beverly L. Davidson

    Published 2014
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  10. 10
    A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

    A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor by S Pollitt, Judit Pallos, Jieya Shao, Urvee A. Desai, Aye Aye K., Leslie M. Thompson, J. Lawrence Marsh, Marc I. Diamond

    Published 2003
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  11. 11
    Biologically active molecules that reduce polyglutamine aggregation and toxicity

    Biologically active molecules that reduce polyglutamine aggregation and toxicity by Urvee A. Desai, Judit Pallos, Aye Aye K., Brent R. Stockwell, Leslie M. Thompson, J. Lawrence Marsh, Marc I. Diamond

    Published 2006
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  12. 12
    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo

    PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington’s Disease-Associated Phenotypes In Vivo by Joseph Ochaba, Alex Mas Monteys, Jacqueline G. O’Rourke, Jack C. Reidling, Joan S. Steffan, Beverly L. Davidson, Leslie M. Thompson

    Published 2016
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  13. 13
    Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia

    Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia by William R. Wilcox, Patricia L. Tavormina, Deborah Krakow, Hiroshi Kitoh, Ralph S. Lachman, John J. Wasmuth, Leslie M. Thompson, David L. Rimoin

    Published 1998
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  14. 14
    Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo

    Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo by Justin Legleiter, Emily J Mitchell, Gregor P. Lotz, Ellen Sapp, Che-Ping Ng, Marian DiFiglia, Leslie M. Thompson, Paul J. Muchowski

    Published 2010
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  15. 15
    Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins

    Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins by Gianna Fote, Nicolette R. Geller, Nikolaos E. Efstathiou, Nathan G. Hendricks, Demetrios G. Vavvas, Jack C. Reidling, Leslie M. Thompson, Joan S. Steffan

    Published 2022
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  16. 16
    Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i>

    Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i> by Namita Agrawal, Judit Pallos, Natalia Slepko, Barbara L. Apostol, László Bodai, Ling-Wen Chang, Ann‐Shyn Chiang, Leslie M. Thompson, J. Lawrence Marsh

    Published 2005
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  17. 17
    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

    Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice by Xiaofeng Gu, Erin R. Greiner, Rakesh K. Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S. Steffan, Leslie M. Thompson, Ronald Wetzel, X. William Yang

    Published 2009
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  18. 18
    Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle

    Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle by Gregor P. Lotz, Justin Legleiter, Rebecca Aron, Emily J Mitchell, Shao-Yi Huang, Che-Ping Ng, Charles Glabe, Leslie M. Thompson, Paul J. Muchowski

    Published 2010
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  19. 19
    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

    Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's diseas... by Kuan-Yu Liu, Yu‐Chiau Shyu, Brett A. Barbaro, Yuan-Ta Lin, Yijuang Chern, Leslie M. Thompson, Che-Kun James Shen, J. Lawrence Marsh

    Published 2014
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  20. 20
    The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

    The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription by Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković, Marilee Greenwald, Yazhen Zhu, Heike Göhler, Erich E. Wanker, Gillian P. Bates, David E. Housman, Leslie M. Thompson

    Published 2000
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