Ohcanbohtosat - Leslie M. Thompson
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Drosophila in the Study of Neurodegenerative Disease Dahkki J. Lawrence Marsh, Leslie M. Thompson
Almmustuhtton 2006Revisão -
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Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase Dahkki Lee McAlister-Henn, Leslie M. Thompson
Almmustuhtton 1987Artigo -
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Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins Dahkki Natalia Slepko, Arkka Bhattacharyya, George R. Jackson, Joan S. Steffan, J. Lawrence Marsh, Leslie M. Thompson, Ronald Wetzel
Almmustuhtton 2006Artigo -
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Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau Dahkki Kim N. Green, Joan S. Steffan, Hilda Martínez‐Coria, Xuemin Sun, Steven S. Schreiber, Leslie M. Thompson, Frank M. LaFerla
Almmustuhtton 2008Artigo -
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Molecular, radiologic, and histopathologic correlations in thanatophoric dysplasia Dahkki William R. Wilcox, Patricia L. Tavormina, Deborah Krakow, Hiroshi Kitoh, Ralph S. Lachman, John J. Wasmuth, Leslie M. Thompson, David L. Rimoin
Almmustuhtton 1998Artigo -
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Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo Dahkki Justin Legleiter, Emily J Mitchell, Gregor P. Lotz, Ellen Sapp, Che-Ping Ng, Marian DiFiglia, Leslie M. Thompson, Paul J. Muchowski
Almmustuhtton 2010Artigo -
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Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins Dahkki Gianna Fote, Nicolette R. Geller, Nikolaos E. Efstathiou, Nathan G. Hendricks, Demetrios G. Vavvas, Jack C. Reidling, Leslie M. Thompson, Joan S. Steffan
Almmustuhtton 2022Artigo -
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Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i> Dahkki Namita Agrawal, Judit Pallos, Natalia Slepko, Barbara L. Apostol, László Bodai, Ling-Wen Chang, Ann‐Shyn Chiang, Leslie M. Thompson, J. Lawrence Marsh
Almmustuhtton 2005Artigo -
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Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice Dahkki Xiaofeng Gu, Erin R. Greiner, Rakesh K. Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S. Steffan, Leslie M. Thompson, Ronald Wetzel, X. William Yang
Almmustuhtton 2009Artigo -
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Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle Dahkki Gregor P. Lotz, Justin Legleiter, Rebecca Aron, Emily J Mitchell, Shao-Yi Huang, Che-Ping Ng, Charles Glabe, Leslie M. Thompson, Paul J. Muchowski
Almmustuhtton 2010Artigo -
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Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's diseas... Dahkki Kuan-Yu Liu, Yu‐Chiau Shyu, Brett A. Barbaro, Yuan-Ta Lin, Yijuang Chern, Leslie M. Thompson, Che-Kun James Shen, J. Lawrence Marsh
Almmustuhtton 2014Artigo -
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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription Dahkki Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković, Marilee Greenwald, Yazhen Zhu, Heike Göhler, Erich E. Wanker, Gillian P. Bates, David E. Housman, Leslie M. Thompson
Almmustuhtton 2000Artigo
Ohcanreaiddut:
Laktáseaddji fáttát
Biology
Gene
Genetics
Cell biology
Medicine
Disease
Huntingtin
Mutant
Huntington's disease
Pathology
Neuroscience
Biochemistry
Huntingtin Protein
Chemistry
Internal medicine
Neurodegeneration
Molecular biology
Embryonic stem cell
Induced pluripotent stem cell
Allele
Computational biology
Immunology
Phenotype
Trinucleotide repeat expansion
Gene expression
Protein aggregation
Amyotrophic lateral sclerosis
Enzyme
Pharmacology
Receptor