Výsledky vyhledávání - Leggy A. Arnold

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  1. 1
    Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord

    Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord Autor Molly E. Drosen, Sarojini R. Bulbule, Gunnar Gottschalk, Daniel L. Peterson, Linda A. Allen, Leggy A. Arnold, Avik Roy

    Vydáno 2025
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  2. 2
    Inhibition of a viral enzyme by a small-molecule dimer disruptor

    Inhibition of a viral enzyme by a small-molecule dimer disruptor Autor Tina Shahian, Gregory M. Lee, Ana Lazic, Leggy A. Arnold, Priya Velusamy, Christina M Roels, R. Kiplin Guy, Charles S. Craik

    Vydáno 2009
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  3. 3
    Quantification of the Vitamin D Receptor−Coregulator Interaction

    Quantification of the Vitamin D Receptor−Coregulator Interaction Autor Arnaud Teichert, Leggy A. Arnold, Steve Otieno, Yuko Oda, Indre Augustinaite, Tim Geistlinger, Richard W. Kriwacki, R. Kiplin Guy, Daniel D. Bikle

    Vydáno 2009
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  4. 4
    Structural Insight into the Mode of Action of a Direct Inhibitor of Coregulator Binding to the Thyroid Hormone Receptor

    Structural Insight into the Mode of Action of a Direct Inhibitor of Coregulator Binding to the Thyroid Hormone Receptor Autor Eva Estébanez‐Perpiñá, Leggy A. Arnold, Natalia Jouravel, Marie Togashi, Justin D. Blethrow, Ellena Mar, Phuong Nguyen, Kevin J. Phillips, John D. Baxter, Paul Webb, R. Kiplin Guy, Robert J. Fletterick

    Vydáno 2007
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  5. 5
    Discovery of Small Molecule Inhibitors of the Interaction of the Thyroid Hormone Receptor with Transcriptional Coregulators

    Discovery of Small Molecule Inhibitors of the Interaction of the Thyroid Hormone Receptor with Transcriptional Coregulators Autor Leggy A. Arnold, Eva Estébanez‐Perpiñá, Marie Togashi, Natalia Jouravel, Anang A. Shelat, Andrea C. McReynolds, Ellena Mar, Phuong Nguyen, John D. Baxter, Robert J. Fletterick, Paul Webb, R. Kiplin Guy

    Vydáno 2005
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  6. 6
    A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model

    A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model Autor Terry Clayton, Michael M. Poe, Sundari Rallapalli, Poonam Biawat, Miroslav M. Savić, James K. Rowlett, George Gallos, Charles W. Emala, Catherine C. Kaczorowski, Douglas C. Stafford, Leggy A. Arnold, James M. Cook

    Vydáno 2015
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    Revisão
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  7. 7
    A surface on the androgen receptor that allosterically regulates coactivator binding

    A surface on the androgen receptor that allosterically regulates coactivator binding Autor Eva Estébanez‐Perpiñá, Leggy A. Arnold, Phuong Nguyen, Edson Delgado Rodrigues, Ellena Mar, Raynard L. Bateman, Peter V. Pallai, Kevan M. Shokat, John D. Baxter, R. Kiplin Guy, Paul Webb, Robert J. Fletterick

    Vydáno 2007
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  8. 8
    Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

    Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays Autor Sourav Mukherjee, Alicia M. Hanson, William R. Shadrick, Jean Ndjomou, Noreena L. Sweeney, John J. Hernandez, Diana Bartczak, Kelin Li, Kevin J. Frankowski, Julie A. Heck, Leggy A. Arnold, Frank J. Schoenen, David N. Frick

    Vydáno 2012
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  9. 9
    Identification of a novel, fast-acting GABAergic antidepressant

    Identification of a novel, fast-acting GABAergic antidepressant Autor Katherine M.J. McMurray, Marcia J. Ramaker, Amanda M. Barkley‐Levenson, Preetpal S. Sidhu, Pavel K. Elkin, Michael K. Reddy, Margaret L. Guthrie, J. M. Cook, Viresh H. Rawal, Leggy A. Arnold, Stephanie C. Dulawa, Abraham A. Palmer

    Vydáno 2017
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  10. 10
    Identification and Characterization of the First Small Molecule Inhibitor of MDMX

    Identification and Characterization of the First Small Molecule Inhibitor of MDMX Autor Damon R. Reed, Ying Shen, Anang A. Shelat, Leggy A. Arnold, Antonio M. Ferreira, Fangyi Zhu, Nicholas L. Mills, David C. Smithson, C.A. Regni, Donald Bashford, Samantha A. Cicero, Brenda A. Schulman, Aart G. Jochemsen, R. Kiplin Guy, Michael A. Dyer

    Vydáno 2010
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  11. 11
    Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles

    Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles Autor Thomas D. Prévot, Guanguan Li, Aleksandra Vidojević, Keith A. Misquitta, Corey Fee, Anja Santrač, Daniel E. Knutson, Michael Rajesh Stephen, Revathi Kodali, Nicolas M. Zahn, Leggy A. Arnold, Petra Scholze, Janet L. Fisher, Bojan Marković, Mounira Banasr, James M. Cook, Miroslav M. Savić, Etienne Sibille

    Vydáno 2019
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  12. 12
    Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA<sub>A</sub>) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy

    Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA<sub>A</sub>) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxioly... Autor Michael M. Poe, Kashi Reddy Methuku, Guanguan Li, Ashwini R. Verma, Kelly A. Teske, Douglas C. Stafford, Leggy A. Arnold, Jeffrey W. Cramer, Timothy M. Jones, Rok Cerne, Michael J. Krambis, Jeffrey M. Witkin, Enrique Jambrina, Sabah Rehman, Margot Ernst, James M. Cook, Jeffrey M. Schkeryantz

    Vydáno 2016
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  13. 13
    An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma

    An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma Autor Jennifer M. Atkinson, Anang A. Shelat, Ángel M. Carcaboso, Tanya A. Kranenburg, Leggy A. Arnold, Nidal Boulos, Karen Wright, Robert A. Johnson, Helen Poppleton, Kumarasamypet M. Mohankumar, Clémentine Féau, Timothy N. Phoenix, Paul Gibson, Liqin Zhu, Yiai Tong, C.G. van Eden, David W. Ellison, Waldemar Priebe, Dimpy Koul, W.K. Alfred Yung, Amar Gajjar, Clinton F. Stewart, R. Kiplin Guy, Richard J. Gilbertson

    Vydáno 2011
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