Resultados de procura - Lakshmi Muthuswamy

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  1. 1
    Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids

    Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids por Ling Huang, Ridhdhi Desai, Daniel N. Conrad, Nayara C. Leite, Dipikaa Akshinthala, Christine Lim, Raul S. González, Lakshmi Muthuswamy, Zev J. Gartner, Senthil K. Muthuswamy

    Publicado 2021
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  2. 2
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors

    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors por Nealia C. House, Victoria E. Brown, Maxine Chen, Liang Yuan, Sydney L. Moore, Jian Guo, Yoon Jong Choi, Lakshmi Muthuswamy, Scott Ribich, Philip Ramsden, L. Kerrie

    Publicado 2025
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  3. 3
    Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

    Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism por Guy Horev, Jacob Ellegood, Jason P. Lerch, Young-Eun E. Son, Lakshmi Muthuswamy, Hannes Vogel, Abba Μ. Krieger, Andreas Buja, R. Mark Henkelman, Michael Wigler, Alea A. Mills

    Publicado 2011
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  4. 4
    Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer

    Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer por Michael E. Feigin, S. Dipikaa Akshinthala, Kiyomi Y. Araki, Avi Z. Rosenberg, Lakshmi Muthuswamy, Bernard Martin, Brian D. Lehmann, Hal K. Berman, Jennifer A. Pietenpol, Robert D. Cardiff, Senthil K. Muthuswamy

    Publicado 2014
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  5. 5
    Tumour evolution inferred by single-cell sequencing

    Tumour evolution inferred by single-cell sequencing por Nicholas E. Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito, Lakshmi Muthuswamy, A. Krasnitz, W. Richard McCombie, James Hicks, Michael Wigler

    Publicado 2011
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  6. 6
    Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact

    Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact por Lei Li, Yu‐Hong Wei, Christine To, Chang‐Qi Zhu, Jiefei Tong, Nhu‐An Pham, Paul Taylor, Vladimir Ignatchenko, Alexandr Ignatchenko, Wen Zhang, Dennis Wang, Naoki Yanagawa, Ming Li, Melania Pintilie, Geoffrey Liu, Lakshmi Muthuswamy, Frances A. Shepherd, Ming‐Sound Tsao, Thomas Kislinger, Michael F. Moran

    Publicado 2014
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  7. 7
    RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation

    RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation por Robert A. Jones, Tyler Robinson, Jeff C. Liu, Mariusz Shrestha, Véronique Voisin, YoungJun Ju, Philip E.D. Chung, Giovanna Pellecchia, Victoria L. Fell, Sooin Bae, Lakshmi Muthuswamy, Alessandro Datti, Sean E. Egan, Zhe Jiang, Gustavo Leone, Gary D. Bader, Aaron D. Schimmer, Eldad Zacksenhaus

    Publicado 2016
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  8. 8
    Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

    Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids por Ling Huang, Audrey Holtzinger, Ishaan Jagan, Michael D. BeGora, Ines Lohse, Nicholas Ngai, M. Cristina Nostro, Rennian Wang, Lakshmi Muthuswamy, Howard C. Crawford, C.H. Arrowsmith, Steve E. Kalloger, Daniel J. Renouf, Ashton A. Connor, Sean P. Cleary, David F. Schaeffer, Michael H. A. Roehrl, Ming‐Sound Tsao, Steven Gallinger, Gordon Keller, Senthil K. Muthuswamy

    Publicado 2015
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  9. 9
    PDX-derived organoids model in vivo drug response and secrete biomarkers

    PDX-derived organoids model in vivo drug response and secrete biomarkers por Ling Huang, Bruno Bockorny, Indranil Paul, Dipikaa Akshinthala, Pierre‐Olivier Frappart, Omar Gandarilla, Arindam Bose, Veronica Sanchez‐Gonzalez, Emily E. Rouse, Sylvain Lehoux, Nicole Pandell, Christine Lim, John G. Clohessy, Joseph E. Grossman, Raul S. González, Sofia Perea Del Pino, George Daaboul, Mandeep Sawhney, Steven D. Freedman, Alexander Kleger, Richard D. Cummings, Andrew Emili, Lakshmi Muthuswamy, Manuel Hidalgo, Senthil K. Muthuswamy

    Publicado 2020
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  10. 10
    Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer

    Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer por Joseph E. Grossman, Lakshmi Muthuswamy, Ling Huang, Dipikaa Akshinthala, Sofía Perea, Raul S. González, Leo L. Tsai, Jonah N. Cohen, Bruno Bockorny, Andrea J. Bullock, Benjamin L. Schlechter, Mary Linton B. Peters, Catherine Conahan, Supraja Narasimhan, Christine Lim, Roger B. Davis, Robert J. Besaw, Mandeep Sawhney, Douglas K. Pleskow, Tyler M. Berzin, Martin A. Smith, Tara S. Kent, Mark P. Callery, Senthil K. Muthuswamy, Manuel Hidalgo

    Publicado 2021
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  11. 11
    Computational approaches to identify functional genetic variants in cancer genomes

    Computational approaches to identify functional genetic variants in cancer genomes por Abel González-Pérez, Ville Mustonen, Boris Reva, Graham R. S. Ritchie, Pau Creixell, Rachel Karchin, Miguél Vázquez, J. Lynn Fink, Karin S. Kassahn, John V. Pearson, Gary D. Bader, Paul C. Boutros, Lakshmi Muthuswamy, B. F. Francis Ouellette, Jüri Reimand, Rune Linding, Tatsuhiro Shibata, Alfonso Valencia, Adam P. Butler, Serge Dronov, Paul Flicek, Nicholas B. Shannon, Hannah Carter, Li Ding, Chris Sander, Joshua M. Stuart, Lincoln Stein, Núria López-Bigas

    Publicado 2013
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  12. 12
    Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors

    Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors por Dennis Wang, Nhu‐An Pham, Jiefei Tong, Shingo Sakashita, Ghassan Allo, Lucia Kim, Naoki Yanagawa, Vibha Raghavan, Yu‐Hong Wei, Christine To, Quang M. Trinh, Maud H. W. Starmans, Michelle Chan‐Seng‐Yue, Dianne Chadwick, Lei Li, Chang‐Qi Zhu, Ni Liu, Ming Li, Sharon Lee, Vladimir Ignatchenko, Dan Strumpf, Paul Taylor, Nadeem Moghal, Geoffrey Liu, Paul C. Boutros, Thomas Kislinger, Melania Pintilie, Igor Jurišica, Frances A. Shepherd, John D. McPherson, Lakshmi Muthuswamy, Michael F. Moran, Ming‐Sound Tsao

    Publicado 2016
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  13. 13
    Spatial genomic heterogeneity within localized, multifocal prostate cancer

    Spatial genomic heterogeneity within localized, multifocal prostate cancer por Paul C. Boutros, Michael Fraser, Nicholas J. Harding, Richard de Borja, Dominique Trudel, Emilie Lalonde, Alice Meng, Pablo H. Hennings-Yeomans, Andrew McPherson, Veronica Y. Sabelnykova, Amin Zia, Natalie S. Fox, Julie Livingstone, Yu-Jia Shiah, Jianxin Wang, Timothy A. Beck, Cherry Have, Taryne Chong, Michelle Sam, Jeremy Johns, Lee E. Timms, Nicholas Buchner, Ada Wong, John D. Watson, Trent T Simmons, Christine P’ng, Gaetano Zafarana, Francis Nguyen, Xuemei Luo, Kenneth C. Chu, Stephenie D. Prokopec, Jenna Sykes, Alan Dal Pra, Alejandro Berlín, Andrew Brown, Michelle Chan‐Seng‐Yue, Fouad Yousif, Robert E. Denroche, Lauren C. Chong, Gregory M. Chen, Esther Jung, Clement Fung, Maud H. W. Starmans, Hanbo Chen, Shaylan K. Govind, James R. Hawley, Alister D’Costa, Melania Pintilie, Daryl Waggott, Faraz Hach, Philippe Lambin, Lakshmi Muthuswamy, Colin Cooper, Rosalind A. Eeles, David E. Neal, Bernard Têtu, Cenk Sahinalp, Lincoln Stein, Neil Fleshner, Sohrab P. Shah, Colin C. Collins, Thomas J. Hudson, John D. McPherson, Theodorus van der Kwast, Robert G. Bristow

    Publicado 2015
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  14. 14
    Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

    Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes por Andrew V. Biankin, Nicola Waddell, Karin S. Kassahn, Marie‐Claude Gingras, Lakshmi Muthuswamy, Amber L. Johns, David K. Miller, Peter J. Wilson, Ann‐Marie Patch, Jianmin Wu, David K. Chang, Mark J. Cowley, Brooke Gardiner, Sarah Song, Ivon Harliwong, Senel Idrisoglu, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Milena Gongora, Marina Pajic, Christopher J. Scarlett, Anthony J. Gill, Andreia V. Pinho, Ilse Rooman, Matthew J. Anderson, Oliver Holmes, Conrad Leonard, Darrin F. Taylor, Scott Wood, Qinying Xu, Kátia Nones, J. Lynn Fink, Angelika N. Christ, Timothy J. C. Bruxner, Nicole Cloonan, Gabriel Kolle, Felicity Newell, Mark Pinese, R. Scott Mead, Jeremy L. Humphris, Warren Kaplan, Marc D. Jones, Emily K. Colvin, Adnan Nagrial, Emily S. Humphrey, Angela Chou, Venessa Chin, Lorraine A. Chantrill, Amanda Mawson, Jaswinder S. Samra, James G. Kench, Jessica A. Lovell, Roger J. Daly, Neil D. Merrett, Christopher W. Toon, Krishna Epari, Nam Q. Nguyen, Andrew P. Barbour, Nikolajs Zeps, Nipun Kakkar, Fengmei Zhao, Yuan Wu, Min Wang, Donna M. Muzny, William E. Fisher, F. Charles Brunicardi, Sally E. Hodges, Jeffrey G. Reid, Jennifer Drummond, Kyle Chang, Yi Han, Lora Lewis, Huyen Dinh, Christian Buhay, Timothy A. Beck, Lee E. Timms, Michelle Sam, Kimberly Begley, Andrew Brown, Deepa Pai, Ami Panchal, Nicholas Buchner, Richard de Borja, Robert E. Denroche, Christina K. Yung, Stefano Serra, Nicole Onetto, Debabrata Mukhopadhyay, Ming‐Sound Tsao, Patricia A. Shaw, Gloria M. Petersen, Steven Gallinger, Ralph H. Hruban, Anirban Maitra, Christine A. Iacobuzio‐Donahue, Richard D. Schulick, Christopher L. Wolfgang, Richard A. Morgan

    Publicado 2012
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