检索结果 - L. Austin Doyle
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Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures 由 Vivek Subbiah, Aung Naing, Robert Brown, Helen Chen, L. Austin Doyle, Patricia LoRusso, Robert S. Benjamin, Pete Anderson, Razelle Kurzrock
出版 2011Artigo -
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Insulin growth factor receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with metastatic adrenocortical carcinoma 由 Aung Naing, Patricia LoRusso, Siqing Fu, David S. Hong, H. X. Chen, L. Austin Doyle, Alexandria T. Phan, Mouhammed Amir Habra, Razelle Kurzrock
出版 2013Artigo -
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High-dose radiotherapy in trimodality treatment of Pancoast tumors results in high pathologic complete response rates and excellent long-term survival 由 King F. Kwong, Martin J. Edelman, Mohan Suntharalingam, Lindsay B. Cooper, Ziv Gamliel, W. Burrows, P Hausner, L. Austin Doyle, Mark J. Krasna
出版 2005Artigo -
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Phase II study of cixutumumab in combination with temsirolimus in pediatric patients and young adults with recurrent or refractory sarcoma: A report from the children's oncology gr... 由 Lars M. Wagner, Maryam Fouladi, Atif Ahmed, Mark Krailo, Brenda J. Weigel, Steven G. DuBois, L. Austin Doyle, Helen Chen, Susan M. Blaney
出版 2014Artigo -
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Insulin Growth Factor-Receptor (IGF-1R) Antibody Cixutumumab Combined with the mTOR Inhibitor Temsirolimus in Patients with Refractory Ewing's Sarcoma Family Tumors 由 Aung Naing, Patricia LoRusso, Siqing Fu, David S. Hong, Pete Anderson, Robert S. Benjamin, Joseph A. Ludwig, Helen X. Chen, L. Austin Doyle, Razelle Kurzrock
出版 2012Artigo -
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Atypical Multidrug Resistance: Breast Cancer Resistance Protein Messenger RNA Expression in Mitoxantrone-Selected Cell Lines 由 D D Ross, Weidong Yang, Lynne V. Abruzzo, William S. Dalton, E Schneider, Hermann Lage, Manfred Dietel, Lee M. Greenberger, Susan P.C. Cole, L. Austin Doyle
出版 1999Artigo -
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Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer 由 T. Khanh, Giovanna Speranza, Rachel Bishop, Sonny Khin, Larry Rubinstein, Robert J. Kinders, Manuel B. Datiles, Michelle Eugeni, Michael Lam, L. Austin Doyle, James H. Doroshow, Shivaani Kummar
出版 2015Artigo -
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Temsirolimus Has Activity in Non–Mantle Cell Non-Hodgkin's Lymphoma Subtypes: The University of Chicago Phase II Consortium 由 Sonali M. Smith, Koen van Besien, Theodore Karrison, Janet Dancey, Peter McLaughlin, Anas Younes, Scott E. Smith, Patrick J. Stiff, Eric P. Lester, Sanjiv Modi, L. Austin Doyle, Everett E. Vokes, Barbara Pro
出版 2010Artigo -
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Phase I Trial of Cixutumumab Combined with Temsirolimus in Patients with Advanced Cancer 由 Aung Naing, Razelle Kurzrock, Angelika M. Burger, Sachin Gupta, Xiudong Lei, Naifa L. Busaidy, David S. Hong, Helen X. Chen, L. Austin Doyle, Lance K. Heilbrun, Eric Rohren, Chaan S. Ng, Chandtip Chandhasin, Patricia LoRusso
出版 2011Artigo -
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A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours 由 Breelyn A. Wilky, Michelle A. Rudek, Shabina Roohi Ahmed, Dan Laheru, David Cosgrove, Ross C. Donehower, Barry D. Nelkin, Douglas W. Ball, L. Austin Doyle, H Chen, X Ye, Graham Bigley, Chris Womack, Nilofer S. Azad
出版 2014Artigo -
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Combination of Temsirolimus (CCI-779) with Chemoradiation in Newly Diagnosed Glioblastoma Multiforme (GBM) (NCCTG trial N027D) Is Associated with Increased Infectious Risks 由 Jann N. Sarkaria, E. Galanis, Wenting Wu, Allan B. Dietz, Timothy J. Kaufmann, Michael P. Gustafson, Paul D. Brown, Joon H. Uhm, Ravi D. Rao, L. Austin Doyle, Caterina Giannini, Kurt A. Jaeckle, Jan C. Buckner
出版 2010Artigo -
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A Phase I Study of Dinaciclib in Combination With MK‐2206 in Patients With Advanced Pancreatic Cancer 由 Adrian Murphy, Marianna Zahurak, Mirat Shah, Colin D. Weekes, Aaron R. Hansen, Lillian L. Siu, Anna Spreafico, Noelle K. LoConte, Nicole M. Anders, T. Miles, Michelle A. Rudek, L. Austin Doyle, Barry D. Nelkin, Anirban Maitra, Nilofer S. Azad
出版 2020Artigo -
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Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia 由 Judith E. Karp, Amanda L. Blackford, B. Douglas Smith, Katrina Alino, Amy Hatfield Seung, Javier Bolaños‐Meade, Jacqueline M. Greer, Hetty E. Carraway, Steven D. Gore, Richard J. Jones, Mark J. Levis, Michael A. McDevitt, L. Austin Doyle, James R. Wright
出版 2009Artigo -
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Effect of Selumetinib and MK-2206 vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy 由 Vincent Chung, Shannon McDonough, Philip A. Philip, Dana B. Cardin, Andrea Wang‐Gillam, Laifong Hui, Mohamedtaki Abdulaziz Tejani, Tara Elisabeth Seery, Irene Dy, Tareq Al Baghdadi, Andrew Hendifar, L. Austin Doyle, Andrew M. Lowy, Katherine A. Guthrie, Charles D. Blanke, Howard S. Höchster
出版 2016Artigo -
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Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia 由 Jonathan Webster, Raoul Tibes, Larry Morris, Amanda L. Blackford, Mark R. Litzow, Mrinal M. Patnaik, Gary L. Rosner, Ivana Gojo, Robert J. Kinders, Lihua Wang, L. Austin Doyle, Catherine J. Huntoon, Larry M. Karnitz, Scott H. Kaufmann, Judith E. Karp, B. Douglas Smith
出版 2017Artigo -
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Multi-Institutional Phase II Study of Selumetinib in Patients With Metastatic Biliary Cancers 由 Tanios Bekaii‐Saab, Mitch A. Phelps, Xiaobai Li, Motoyasu Saji, Laura W. Goff, John Kauh, Bert H. O’Neil, Stephanie Balsom, Catherine Balint, R. Liersemann, Vasily Vasko, Mark Bloomston, W. Marsh, L. Austin Doyle, Gilian Ellison, Michael R. Grever, Matthew D. Ringel, Miguel A. Villalona‐Calero
出版 2011Artigo -
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Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias 由 Judith E. Karp, Benjamin D. Smith, Linda Resar, Jacqueline M. Greer, Amanda L. Blackford, Ming Zhao, Dwella Moton-Nelson, Katrina Alino, Mark J. Levis, Steven D. Gore, Biju Joseph, Hetty E. Carraway, Michael A. McDevitt, Lorena Bagain, Karen Mackey, Janet Briel, L. Austin Doyle, James R. Wright, Michelle A. Rudek
出版 2011Artigo
相关主题
Medicine
Internal medicine
Oncology
Cancer
Biology
Biochemistry
Chemotherapy
Cancer research
Colorectal cancer
Selumetinib
Apoptosis
KRAS
Gastroenterology
PI3K/AKT/mTOR pathway
Chemistry
Clinical trial
Discovery and development of mTOR inhibitors
Leukemia
Pharmacology
Protein kinase B
Temsirolimus
Mucositis
Adverse effect
Gene
Genetics
Kinase
MAPK/ERK pathway
MEK inhibitor
Mitoxantrone
Surgery