Výsledky vyhledávání - Krushna C. Patra

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  1. 1
    The pentose phosphate pathway and cancer

    The pentose phosphate pathway and cancer Autor Krushna C. Patra, Nissim Hay

    Vydáno 2014
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  2. 2
    Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm

    Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm Autor Krushna C. Patra, Nabeel Bardeesy, Yusuke Mizukami

    Vydáno 2017
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  3. 3
    Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation

    Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation Autor Véronique Nogueira, Krushna C. Patra, Nissim Hay

    Vydáno 2018
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  4. 4
    Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

    Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin Autor Dannielle C. DeWaal, Véronique Nogueira, Alexander R. Terry, Krushna C. Patra, Sang‐Min Jeon, Grace Guzman, Jennifer Au, Christopher P. Long, Maciek R. Antoniewicz, Nissim Hay

    Vydáno 2018
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  5. 5
    DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer

    DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer Autor Nilotpal Roy, Prashant V. Bommi, Uppoor G. Bhat, Shaumick Bhattacharjee, Indira Elangovan, Jing Li, Krushna C. Patra, Dragana Kopanja, Adam Blunier, Richard V. Benya, Srilata Bagchi, Pradip Raychaudhuri

    Vydáno 2013
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  6. 6
    <i>Kras</i> and <i>Tp53</i> Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma

    <i>Kras</i> and <i>Tp53</i> Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma Autor Margaret Hill, W. Brock Alexander, Bing Guo, Yasutaka Kato, Krushna C. Patra, Michael R. O’Dell, Matthew N. McCall, Christa L. Whitney‐Miller, Nabeel Bardeesy, Aram F. Hezel

    Vydáno 2018
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  7. 7
    A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

    A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis Autor Catherine Blaha, Gopalakrishnan Ramakrishnan, Sang‐Min Jeon, Véronique Nogueira, Hyunsoo Rho, Soeun Kang, Prashanth T. Bhaskar, Alexander R. Terry, Alexandre F. Aissa, Maxim V. Frolov, Krushna C. Patra, R. Brooks Robey, Nissim Hay

    Vydáno 2022
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  8. 8
    Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

    Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer Autor Krushna C. Patra, Qi Wang, Prashanth T. Bhaskar, Luke Miller, Zebin Wang, Will Wheaton, Navdeep S. Chandel, Markku Laakso, William J. Muller, Eric L. Allen, Abhishek Jha, Gromoslaw A. Smolen, Michelle Clasquin, R. Brooks Robey, Nissim Hay

    Vydáno 2013
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  9. 9
    REDD1 loss reprograms lipid metabolism to drive progression of <i>RAS</i> mutant tumors

    REDD1 loss reprograms lipid metabolism to drive progression of <i>RAS</i> mutant tumors Autor Shuxi Qiao, Siang‐Boon Koh, Varunika Vivekanandan, Devika Salunke, Krushna C. Patra, Elma Zaganjor, Kenneth N. Ross, Yusuke Mizukami, Sarah Jeanfavre, Athena L. Chen, Mari Mino‐Kenudson, Sridhar Ramaswamy, Clary B. Clish, Marcia C. Haigis, Nabeel Bardeesy, Leif W. Ellisen

    Vydáno 2020
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  10. 10
    Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

    Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism Autor Krushna C. Patra, Yasutaka Kato, Yusuke Mizukami, Sebastian A. Widholz, Myriam Boukhali, Iulia Revenco, Elizabeth Grossman, Fei Ji, Ruslan I. Sadreyev, Andrew S. Liss, Robert A. Screaton, Kei Sakamoto, David P. Ryan, Mari Mino‐Kenudson, Carlos Fernández‐del Castillo, Daniel K. Nomura, Wilhelm Haas, Nabeel Bardeesy

    Vydáno 2018
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  11. 11
    Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms

    Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms Autor Gary K.L. Chan, Samantha Maisel, Yeonjoo Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu, Krushna C. Patra, Mehdi Bouhaddou, Heidi L. Kenerson, Huat Chye Lim, Donald Long, Raymond S. Yeung, Praveen Sethupathy, Danielle L. Swaney, Nevan J. Krogan, Rigney E. Turnham, Kimberly J. Riehle, John D. Scott, Nabeel Bardeesy, John D. Gordan

    Vydáno 2023
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  12. 12
    Data from DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming

    Data from DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming Autor Ilaria Gritti, Jinkai Wan, Vajira Weeresekara, Joel Markus Vaz, Giuseppe Tarantino, Tenna Holgersen Bryde, Vindhya Vijay, Ashwin V. Kammula, Prabhat Kattel, Songli Zhu, Phuong Vu, Marina Chan, Meng‐Ju Wu, John D. Gordan, Krushna C. Patra, Vanessa S. Silveira, Robert T. Manguso, Marc N. Wein, Christopher J. Ott, Jun Qi, David Liu, Kei Sakamoto, Taranjit S. Gujral, Nabeel Bardeesy

    Vydáno 2025
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  13. 13
    TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma

    TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma Autor Lipika Goyal, Lei Shi, Leah Y. Liu, Ferran Fece de la Cruz, Jochen K. Lennerz, Srivatsan Raghavan, Ignaty Leschiner, Liudmila Elagina, Giulia Siravegna, Raymond W.S. Ng, Phuong Vu, Krushna C. Patra, Supriya K. Saha, Raul N. Uppot, Ron Arellano, Stephanie Reyes, Takeshi Sagara, Sachie Otsuki, Brandon Nadres, Heather A. Shahzade, Ipsita Dey‐Guha, Isobel J. Fetter, Islam Baiev, Emily E. Van Seventer, Janet E. Murphy, Cristina R. Ferrone, Kenneth K. Tanabe, Vikram Deshpande, James J. Harding, Rona Yaeger, Robin Kate Kelley, Alberto Bardelli, A. John Iafrate, William C. Hahn, Cyril H. Benes, David T. Ting, Hiroshi Hirai, Gad Getz, Dejan Juric, Andrew X. Zhu, Ryan B. Corcoran, Nabeel Bardeesy

    Vydáno 2019
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