Výsledky vyhledávání - Ken Dutton‐Regester

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  1. 1
    Reviewing the somatic genetics of melanoma: from current to future analytical approaches

    Reviewing the somatic genetics of melanoma: from current to future analytical approaches Autor Ken Dutton‐Regester, Nicholas K. Hayward

    Vydáno 2012
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  2. 2
    The genomic landscape of cutaneous melanoma

    The genomic landscape of cutaneous melanoma Autor Tongwu Zhang, Ken Dutton‐Regester, Kevin M. Brown, Nicholas K. Hayward

    Vydáno 2016
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  3. 3
    Melanoma cell invasiveness is regulated by miR‐211 suppression of the BRN2 transcription factor

    Melanoma cell invasiveness is regulated by miR‐211 suppression of the BRN2 transcription factor Autor Glen M. Boyle, Susan L. Woods, Vanessa Bonazzi, Mitchell Stark, Elke Hacker, Lauren G. Aoude, Ken Dutton‐Regester, Anthony L. Cook, Richard A. Sturm, Nicholas K. Hayward

    Vydáno 2011
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  4. 4
    <i><scp>BRAF</scp></i>/<i><scp>NRAS</scp></i> wild‐type melanoma, <scp>NF</scp>1 status and sensitivity to trametinib

    <i><scp>BRAF</scp></i>/<i><scp>NRAS</scp></i> wild‐type melanoma, <scp>NF</scp>1 status and sensitivity to trametinib Autor Marco Ranzani, Constantine Alifrangis, Daniele Perna, Ken Dutton‐Regester, Antonia L. Pritchard, Kim Wong, Mamunur Rashid, Carla Daniela Robles‐Espinoza, Nicholas K. Hayward, Ultan McDermott, Mathew J. Garnett, David J. Adams

    Vydáno 2014
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  5. 5
    EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma

    EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma Autor Jessamy Tiffen, Stuart Gallagher, Fabian V. Filipp, Dilini Gunatilake, Abdullah Al Emran, Carleen Cullinane, Ken Dutton‐Regester, Lauren G. Aoude, Nicholas K. Hayward, Aniruddha Chatterjee, Euan J. Rodger, Michael R. Eccles, Peter Hersey

    Vydáno 2020
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  6. 6
    Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes

    Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes Autor Jessamy Tiffen, Dilini Gunatilake, Stuart Gallagher, Kavitha Gowrishankar, Anja Heinemann, Carleen Cullinane, Ken Dutton‐Regester, Gulietta M. Pupo, Dario Strbenac, Jean Yang, Jason Madore, Graham J. Mann, Nicholas K. Hayward, Grant A. McArthur, Fabian V. Filipp, Peter Hersey

    Vydáno 2015
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  7. 7
    A highly recurrent RPS27 5'UTR mutation in melanoma

    A highly recurrent RPS27 5'UTR mutation in melanoma Autor Ken Dutton‐Regester, Jared J. Gartner, Rafi Emmanuel, Nouar Qutob, Michael A. Davies, Jeffrey E. Gershenwald, William A. Robinson, Steven E. Robinson, Steven A. Rosenberg, Richard A. Scolyer, Graham J. Mann, John F. Thompson, Nicholas K. Hayward, Yardena Samuels

    Vydáno 2014
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  8. 8
    MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

    MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes Autor Juxiang Cao, Lixin Wan, Elke Hacker, Xiangpeng Dai, Stefania Lenna, Celia Jiménez‐Cervantes, Yongjun Wang, Nicholas R. Leslie, George Xu, Hans R. Widlund, Byungwoo Ryu, Rhoda M. Alani, Ken Dutton‐Regester, Colin R. Goding, Nicholas K. Hayward, Wenyi Wei, Rutao Cui

    Vydáno 2013
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  9. 9
    A High-Throughput Panel for Identifying Clinically Relevant Mutation Profiles in Melanoma

    A High-Throughput Panel for Identifying Clinically Relevant Mutation Profiles in Melanoma Autor Ken Dutton‐Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O’Connor, Michael G. E. OʼRourke, Richard A. Scolyer, Graham J. Mann, Christopher Schmidt, Adrian C. Herington, Nicholas K. Hayward

    Vydáno 2012
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  10. 10
    Loss of <i><scp>CDKN</scp>2A</i> expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the <scp>CDK</scp>4/6 inhibitor <scp>PD</scp>0332991 in melanoma cell lines

    Loss of <i><scp>CDKN</scp>2A</i> expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the <scp>CDK</scp>4/6 inhibitor <scp>PD</scp>0332991... Autor Richard J. Young, Kelly Waldeck, Claire Martin, Jung H. Foo, Donald P. Cameron, Laura Kirby, Hongdo Do, Catherine Mitchell, Carleen Cullinane, Wendy Liu, Stephen B. Fox, Ken Dutton‐Regester, Nicholas K. Hayward, Nicholas Jene, Alexander Dobrovic, Richard B. Pearson, James G. Christensen, Sophia Randolph, Grant A. McArthur, Karen E. Sheppard

    Vydáno 2014
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  11. 11
    Recurrent inactivating RASA2 mutations in melanoma

    Recurrent inactivating RASA2 mutations in melanoma Autor Rand Arafeh, Nouar Qutob, Rafi Emmanuel, Alona Keren‐Paz, Jason Madore, Abdel G. Elkahloun, James S. Wilmott, Jared J. Gartner, Antonella Di Pizio, Sabina Winograd‐Katz, Sivasish Sindiri, Ron Rotkopf, Ken Dutton‐Regester, Peter A. Johansson, Antonia L. Pritchard, Nicola Waddell, Victoria Hill, Jimmy Lin, Yael Hevroni, Steven A. Rosenberg, Javed Khan, Shifra Ben‐Dor, Masha Y. Niv, Igor Ulitsky, Graham J. Mann, Richard A. Scolyer, Nicholas K. Hayward, Yardena Samuels

    Vydáno 2015
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  12. 12
    Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

    Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma Autor Michael Krauthammer, Yong Kong, Byung Hak Ha, Perry Evans, Antonella Bacchiocchi, Jamie P. McCusker, Elaine Cheng, Matthew J. Davis, Gerald Goh, Murim Choi, Stephan Ariyan, Deepak Narayan, Ken Dutton‐Regester, Ana Capatana, Edna C. Holman, Marcus Bosenberg, Mario Sznol, Harriet M. Kluger, Douglas E. Brash, David F. Stern, Miguel A. Materin, Roger S. Lo, Shrikant Mane, Shuangge Ma, Kenneth K. Kídd, Nicholas K. Hayward, Richard P. Lifton, Joseph Schlessinger, Titus J. Boggon, Ruth Halaban

    Vydáno 2012
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  13. 13
    Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

    Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing Autor Mitchell Stark, Susan L. Woods, Michael G. Gartside, Vanessa Bonazzi, Ken Dutton‐Regester, Lauren G. Aoude, Donald Chow, Chris Sereduk, Natalie M. Niemi, Nanyun Tang, Jonathan J. Ellis, Jeffrey G. Reid, Victoria Zismann, Sonika Tyagi, Donna M. Muzny, Irene Newsham, Yuanqing Wu, Jane M. Palmer, Thomas Pollak, David Youngkin, Bradford Brooks, Catherine Lanagan, Christopher Schmidt, Boštjan Kobe, Jeffrey P. MacKeigan, Hongwei Yin, Kevin M. Brown, Richard A. Gibbs, Jeffrey M. Trent, Nicholas K. Hayward

    Vydáno 2011
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  14. 14
    NextGen Voices: Quality mentoring

    NextGen Voices: Quality mentoring Autor Lauren Segal, Divyansh Agarwal, Kyle J. Isaacson, Theresa B. Oehmke, Brijesh Kumar, Jennifer Chen, Joseph Cusimano, Swati Negi, Irina V. Tiper, Adrianus J. Bakermans, Mark Martin Jensen, Edmond Sanganyado, Syed Shan‐e‐Ali Zaidi, Carmen Romero‐Molina, Santiago Esteban Martínez, Sarah M. Anderson, Guilherme Santos, Ana Laura De Lella Ezcurra, Janine Farragher, Vandana Sharma, Gregg A. Duncan, Ken Dutton‐Regester, Sun‐Ae Kim, Yu Sha, Beat A. Schwendimann, Juergen Reichardt, Antarip Halder, Allison F. Dennis, Joel Henrique Ellwanger, Yu‐Han Chiu, Bilal E. Kerman

    Vydáno 2018
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  15. 15
    Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma

    Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma Autor Lauren G. Aoude, Antonia L. Pritchard, Carla Daniela Robles‐Espinoza, Karin Wadt, Mark Harland, Jiyeon Choi, Michael G. Gartside, Vı́ctor Quesada, Peter A. Johansson, Jane M. Palmer, Andrew Ramsay, Xijun Zhang, Kristine Jones, Judith Symmons, Elizabeth A. Holland, Helen Schmid, Vanessa Bonazzi, Susan L. Woods, Ken Dutton‐Regester, Mitchell Stark, Helen Snowden, Remco van Doorn, Grant W. Montgomery, Nicholas G. Martin, Thomas Keane, Carlos López-Otı́n, Anne‐Marie Gerdes, Håkan Olsson, Christian Ingvar, Åke Borg, Nelleke A. Gruis, Jeffrey M. Trent, Göran Jönsson, D. Timothy Bishop, Graham J. Mann, Julia Newton‐Bishop, Kevin M. Brown, David J. Adams, Nicholas K. Hayward

    Vydáno 2014
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  16. 16
    Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

    Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq Autor Itay Tirosh, Benjamin Izar, Sanjay M. Prakadan, Marc H. Wadsworth, Daniel J. Treacy, John J. Trombetta, Asaf Rotem, Christopher Rodman, Christine G. Lian, Gëorge F. Murphy, Mohammad Fallahi‐Sichani, Ken Dutton‐Regester, Jia‐Ren Lin, Ofir Cohen, Parin Shah, Diana Lu, Alex S. Genshaft, Travis Hughes, Carly G.K. Ziegler, Samuel W. Kazer, Aleth Gaillard, Kellie E. Kolb, Alexandra‐Chloé Villani, Cory M. Johannessen, Aleksandr Andreev, Eliezer M. Van Allen, Monica M. Bertagnolli, Peter K. Sorger, Ryan J. Sullivan, Keith T. Flaherty, Dennie T. Frederick, Judit Jané‐Valbuena, Charles H. Yoon, Orit Rozenblatt–Rosen, Alex K. Shalek, Aviv Regev, Levi A. Garraway

    Vydáno 2016
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  17. 17
    A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

    A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma Autor Satoru Yokoyama, Susan L. Woods, Glen M. Boyle, Lauren G. Aoude, Stuart MacGregor, Victoria Zismann, Michael G. Gartside, Anne Ε. Cust, Rizwan Haq, Mark Harland, John Taylor, David L. Duffy, Kelly Nudelman, Ken Dutton‐Regester, Jane M. Palmer, Vanessa Bonazzi, Mitchell Stark, Judith Symmons, Matthew H. Law, Christopher Schmidt, Cathy Lanagan, Linda O’Connor, Elizabeth A. Holland, Helen Schmid, Judith A Maskiell, Jodie Jetann, Megan Ferguson, Mark A. Jenkins, Richard Kefford, Graham G. Giles, Bruce K. Armstrong, Joanne F. Aitken, John L. Hopper, David C. Whiteman, Paul D.P. Pharoah, Douglas F. Easton, Alison M. Dunning, Julia Newton‐Bishop, Grant W. Montgomery, Nicholas G. Martin, Graham J. Mann, D. Timothy Bishop, Hensin Tsao, Jeffrey M. Trent, David E. Fisher, Nicholas K. Hayward, Kevin M. Brown

    Vydáno 2011
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  18. 18
    Whole-genome landscapes of major melanoma subtypes

    Whole-genome landscapes of major melanoma subtypes Autor Nicholas K. Hayward, James S. Wilmott, Nicola Waddell, Peter A. Johansson, Matthew A. Field, Kátia Nones, Ann‐Marie Patch, Hojabr Kakavand, Ludmil B. Alexandrov, Hazel Burke, Valerie Jakrot, Stephen H. Kazakoff, Oliver Holmes, Conrad Leonard, Radhakrishnan Sabarinathan, Loris Mularoni, Scott Wood, Qinying Xu, Nick M. Waddell, Varsha Tembe, Gulietta M. Pupo, Ricardo De Paoli‐Iseppi, Ricardo E. Vilain, Ping Shang, Loretta M. S. Lau, Rebecca A. Dagg, Sarah-Jane Schramm, Antonia L. Pritchard, Ken Dutton‐Regester, Felicity Newell, Anna Fitzgerald, Catherine A. Shang, Sean M. Grimmond, Hilda A. Pickett, Jean Yang, Jonathan R. Stretch, Andreas Behren, Richard Kefford, Peter Hersey, Georgina V. Long, Jonathan Cebon, Mark Shackleton, Andrew J. Spillane, Robyn P.M. Saw, Núria López-Bigas, John V. Pearson, John F. Thompson, Richard A. Scolyer, Graham J. Mann

    Vydáno 2017
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  19. 19
    Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

    Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma Autor Jared J. Gartner, Stephen C. J. Parker, Todd D. Prickett, Ken Dutton‐Regester, Michael L. Stitzel, Jimmy Lin, Sean Davis, Vijaya L. Simhadri, Sujata Jha, Nobuko Katagiri, Valer Gotea, Jamie K. Teer, Xiaomu Wei, Mario A. Morken, Umesh Bhanot, Chen Guo, Laura Elnitski, Michael A. Davies, Hui Shen, Hannah Carter, Rachel Karchin, William H. Robinson, Steven E. Robinson, Steven A. Rosenberg, Francis S. Collins, Giovanni Parmigiani, Anton A. Komar, Chava Kimchi‐Sarfaty, Nicholas K. Hayward, Elliott H. Margulies, Yardena Samuels, Jesse Becker, Betty Benjamin, Robert W. Blakesley, Gerry Bouffard, Shelise Brooks, Holly Coleman, Mila Dekhtyar, Michael D. Gregory, Xiaobin Guan, Jyoti Gupta, Joel Han, April Hargrove, Shi-ling Ho, Taccara Johnson, Richelle Legaspi, Sean Lovett, Quino Maduro, Cathy Masiello, Baishali Maskeri, Jenny McDowell, Casandra Montemayor, James C. Mullikin, Morgan Park, Nancy L. Riebow, Karen Schandler, Brian Schmidt, Christina Sison, Mal Stantripop, James Thomas, Pam Thomas, Meg Vemulapalli, Alice Young

    Vydáno 2013
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