Risultati della ricerca - Jonathan St‐Germain

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  1. 1
    Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth

    Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth di Bo Ram Kim, Étienne Coyaud, Estelle Laurent, Jonathan St‐Germain, Emily Van de Laar, Ming‐Sound Tsao, Brian Raught, Nadeem Moghal

    Pubblicazione 2017
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  2. 2
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges

    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges di Jung Jennifer Ho, Kwang‐Ting Cheng, Cassandra J. Wong, Jonathan St‐Germain, Wade H. Dunham, Brian Raught, Anne‐Claude Gingras, Grant W. Brown

    Pubblicazione 2025
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  3. 3
    A SARS-CoV-2 BioID-based virus-host membrane protein interactome and virus peptide compendium: new proteomics resources for COVID-19 research

    A SARS-CoV-2 BioID-based virus-host membrane protein interactome and virus peptide compendium: new proteomics resources for COVID-19 research di Jonathan St‐Germain, Audrey Astori, Payman Samavarchi‐Tehrani, Hala Abdouni, Vinitha Macwan, Dae‐Kyum Kim, Jennifer J. Knapp, Frederick P. Roth, Anne‐Claude Gingras, Brian Raught

    Pubblicazione 2020
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  4. 4
    Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

    Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome” di Robert Karisch, Minerva Fernandez, Paul Taylor, Carl Virtanen, Jonathan St‐Germain, Lily L. Jin, Isaac S. Harris, Jun Mori, Tak W. Mak, Yotis A. Senis, Arne Östman, Michael F. Moran, Benjamin G. Neel

    Pubblicazione 2011
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  5. 5
    Global Interactomics Uncovers Extensive Organellar Targeting by Zika Virus

    Global Interactomics Uncovers Extensive Organellar Targeting by Zika Virus di Étienne Coyaud, Charlene Ranadheera, D. Cheng, João Gonçalves, Boris J.A. Dyakov, Estelle Laurent, Jonathan St‐Germain, Laurence Pelletier, Anne‐Claude Gingras, John H. Brumell, Peter K. Kim, David Safronetz, Brian Raught

    Pubblicazione 2018
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  6. 6
    Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

    Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation di Yoshihito Kano, Teklab Gebregiworgis, Christopher B. Marshall, Nikolina Radulovich, Betty Poon, Jonathan St‐Germain, Jonathan D. Cook, Ivette Valencia-Sama, Benjamin Grant, Silvia G. Herrera, Jinmin Miao, Brian Raught, Meredith S. Irwin, Jeffrey E. Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming‐Sound Tsao, Mitsuhiko Ikura, Michael Ohh

    Pubblicazione 2019
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  7. 7
    A SARS-CoV-2 – host proximity interactome

    A SARS-CoV-2 – host proximity interactome di Payman Samavarchi‐Tehrani, Hala Abdouni, James D.R. Knight, Audrey Astori, Reuben Samson, Zhen‐Yuan Lin, Dae‐Kyum Kim, Jennifer J. Knapp, Jonathan St‐Germain, Christopher D. Go, Brett Larsen, Cassandra J. Wong, Patricia Cassonnet, Caroline Demeret, Yves Jacob, Frederick P. Roth, Brian Raught, Anne‐Claude Gingras

    Pubblicazione 2020
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  8. 8
    The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability

    The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability di Sara Mirali, Aaron Botham, Véronique Voisin, Changjiang Xu, Jonathan St‐Germain, David Sharon, Fieke W. Hoff, Yihua Qiu, Rose Hurren, Marcela Gronda, Yulia Jitkova, Boaz Nachmias, Neil MacLean, Xiaoming Wang, Andrea Arruda, Mark D. Minden, Terzah M. Horton, Steven M. Kornblau, Steven M. Chan, Gary D. Bader, Brian Raught, Aaron D. Schimmer

    Pubblicazione 2020
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  9. 9
    The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors

    The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors di Teklab Gebregiworgis, Yoshihito Kano, Jonathan St‐Germain, Nikolina Radulovich, Molly L. Udaskin, Ahmet Mentes, Richard Huang, Betty Poon, Wenguang He, Ivette Valencia-Sama, Claire M. Robinson, Melissa Huestis, Jinmin Miao, Jen Jen Yeh, Zhong‐Yin Zhang, Meredith S. Irwin, Jeffrey E. Lee, Ming‐Sound Tsao, Brian Raught, Christopher B. Marshall, Michael Ohh, Mitsuhiko Ikura

    Pubblicazione 2021
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  10. 10
    Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium

    Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial Calcium di Anagha Inguva, Mark J. Althoff, Hunter Tolison, Krysta L. Engel, Maria L. Amaya, Anna E. Krug, Tracy N. Young, Mohammad Minhajuddin, Shanshan Pei, Sweta B. Patel, Amanda Winters, Regan Miller, Ian T. Shelton, Jonathan St‐Germain, Tianyi Ling, Courtney L. Jones, Brian Raught, Austin E. Gillen, Monica Ransom, Sarah Staggs, Clayton A. Smith, Daniel A. Pollyea, Brett M. Stevens, Craig T. Jordan

    Pubblicazione 2024
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  11. 11
    Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity

    Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity di Cristiana O’Brien, Tianyi Ling, Jacob M. Berman, Rachel Culp‐Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan St‐Germain, Vinitha Macwan, Audrey Astori, Andy G.X. Zeng, Jun Young Hong, Meng Li, Min Yang, Sadhan Jana, Fabia Gamboni, Emily Tsao, Weiyi Liu, John E. Dick, Hening Lin, Ari Melnick, Anastasia N. Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D’Alessandro, Courtney L. Jones

    Pubblicazione 2023
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  12. 12
    RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors

    RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors di Parasvi S. Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie‐jo Halaby, Zahra Khan, Luís Palomero, Brandon Ho, Shili Duan, Jonathan St‐Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R. Barnes, Jonathan Beesley, Otto Sánchez, Hal K. Berman, Grant W. Brown, El Bachir Affar, Georgia Chenevix‐Trench, Antonis C. Antoniou, C.H. Arrowsmith, Brian Raught, Miguel Ángel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem

    Pubblicazione 2021
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  13. 13
    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality di Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St‐Germain, Lauren Heese, Grace Egan, Vivian Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith S. Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, Man Chun John, Andrew B. Leber, Mark D. Minden, Walid A. Houry, Hagop M. Kantarjian, Martin Stogniew, Brian Raught, E.F. Pai, Aaron D. Schimmer, Michael Andreeff

    Pubblicazione 2019
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  14. 14
    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells di Rehna Krishnan, Mariah Lapierre, Brandon Gautreau, Kevin C. Nixon, Samah El Ghamrasni, Parasvi S. Patel, Jun Hao, V. Talya Yerlici, Kiran Kumar Naidu Guturi, Jonathan St‐Germain, Francesca Mateo, Amine Saad, Arash Algouneh, Rebecca Earnshaw, Duan Shili, Alma Seitova, Joshua W. Miller, Negin Khosraviani, Adam Penn, Brandon Ho, Otto Sánchez, M. Prakash Hande, Jean‐Yves Masson, Grant W. Brown, Moulay A. Alaoui‐Jamali, John J. Reynolds, C.H. Arrowsmith, Brian Raught, Miguel Ángel Pujana, Karim Mekhail, Grant S. Stewart, Anne Hakem, Razqallah Hakem

    Pubblicazione 2023
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  15. 15
    Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations

    Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations di Dervla M. Connaughton, Rufeng Dai, Danielle Owen, Jonathan Marquez, Nina Mann, Adda L. Graham-Paquin, Makiko Nakayama, Étienne Coyaud, Estelle Laurent, Jonathan St‐Germain, Lot Snijders Blok, Arianna Vino, Verena Klämbt, Konstantin Deutsch, Chen-Han Wilfred Wu, Caroline M. Kolvenbach, Franziska Kause, Isabel Ottlewski, Ronen Schneider, Thomas M. Kitzler, Amar J. Majmundar, Florian Buerger, Ana C. Onuchic-Whitford, Youying Mao, Amy Kolb, Daanya Salmanullah, Evan Chen, Amelie T. van der Ven, Jia Rao, Hadas Ityel, Steve Seltzsam, Johanna M. Rieke, Jing Chen, Asaf Vivante, Daw‐Yang Hwang, Stefan Kohl, Gabriel C. Dworschak, Tobias Hermle, Mariëlle Alders, Tobias Bartolomaeus, Stuart B. Bauer, Michelle A. Baum, Eva H. Brilstra, Thomas D. Challman, Jacob Zyskind, Carrie E. Costin, Katrina M. Dipple, Floor A.M. Duijkers, Marcia Ferguson, David Fitzpatrick, Roger Fick, Ian Glass, Peter J. Hulick, Antonie D. Kline, Ilona Krey, Selvin Kumar, Lu W, Elysa J. Marco, Ingrid M. Wentzensen, Heather C. Mefford, Konrad Platzer, Inna Povolotskaya, Juliann M. Savatt, Н. В. Щербакова, Prabha Senguttuvan, Audrey Squire, Deborah R. Stein, Isabelle Thiffault, V. Yu. Voinova, Michael J. Somers, Michael A. Ferguson, Avram Z. Traum, Ghaleb H. Daouk, Ankana Daga, Nancy Rodig, Paulien A. Terhal, Ellen van Binsbergen, Loai Eid, Velibor Tasić, Hila Milo Rasouly, Tze Y. Lim, Dina Ahram, Ali G. Gharavi, Heiko Reutter, Heidi L. Rehm, Daniel G. MacArthur, Monkol Lek, Kristen M. Laricchia, Richard P. Lifton, Hong Xu, Shrikant Mane, Simone Sanna‐Cherchi, Andrew D. Sharrocks, Brian Raught, Simon E. Fisher, Maxime Bouchard, Mustafa K. Khokha, Shirlee Shril, Friedhelm Hildebrandt

    Pubblicazione 2020
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