Search Results - John P. Morris

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  1. 1
    KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma

    KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma by John P. Morris, Sam C. Wang, Matthias Hebrok

    Published 2010
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  2. 2
    Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation

    Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation by Guido von Figura, John P. Morris, Christopher V.E. Wright, Matthias Hebrok

    Published 2013
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  3. 3
    β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

    β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice by John P. Morris, David A. Cano, Shigeki Sekine, Sam C. Wang, Matthias Hebrok

    Published 2010
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  4. 4
    Expanded RNA-binding activities of mammalian Argonaute 2

    Expanded RNA-binding activities of mammalian Argonaute 2 by Grace Tan, Barry G. Garchow, Xuhang Liu, Jennifer Yeung, John P. Morris, Trinna Cuellar, Michael T. McManus, Marianthi Kiriakidou

    Published 2009
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  5. 5
    A modular and flexible ESC-based mouse model of pancreatic cancer

    A modular and flexible ESC-based mouse model of pancreatic cancer by Michael Saborowski, Anna Saborowski, John P. Morris, Benedikt Bosbach, Lukas E. Dow, Jerry Pelletier, David S. Klimstra, Scott W. Lowe

    Published 2014
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  6. 6
    Arid1a restrains Kras-dependent changes in acinar cell identity

    Arid1a restrains Kras-dependent changes in acinar cell identity by Geulah Livshits, Direna Alonso‐Curbelo, John P. Morris, Richard P. Koche, Michael Saborowski, John E. Wilkinson, Scott W. Lowe

    Published 2018
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  7. 7
    Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis

    Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis by Jennifer P. Morton, Michelle E. Mongeau, David S. Klimstra, John P. Morris, Yie Chia Lee, Yoshiya Kawaguchi, Christopher V.E. Wright, Matthias Hebrok, Brian C. Lewis

    Published 2007
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  8. 8
    Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis

    Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis by Yaqing Zhang, John P. Morris, Wei Yan, Heather Schofield, Austin Gurney, Diane M. Simeone, Sarah E. Millar, Timothy Hoey, Matthias Hebrok, Marina Pasca di Magliano

    Published 2013
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  9. 9
    Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition

    Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition by Chong Chen, Yu Liu, Chao Lü, Justin R. Cross, John P. Morris, Aditya Shroff, Patrick S. Ward, James E. Bradner, Craig B. Thompson, Scott W. Lowe

    Published 2013
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  10. 10
    Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression

    Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression by Akihisa Fukuda, Sam C. Wang, John P. Morris, Alexandra E. Folias, Angela Liou, Grace Kim, Shizuo Akira, Kenneth M. Boucher, Matthew A. Firpo, Sean J. Mulvihill, Matthias Hebrok

    Published 2011
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  11. 11
    Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

    Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma by Janel L. Kopp, Guido von Figura, Erin Mayes, Fenfen Liu, Claire L. Dubois, John P. Morris, Fong Cheng Pan, Haruhiko Akiyama, Christopher V.E. Wright, Kristin C. Jensen, Matthias Hebrok, Maike Sander

    Published 2012
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  12. 12
    A combinatorial strategy for treating KRAS-mutant lung cancer

    A combinatorial strategy for treating KRAS-mutant lung cancer by Eusebio Manchado, Susann Weissmueller, John P. Morris, Chi-Chao Chen, Ramona Wullenkord, Amaia Lujambio, Elisa de Stanchina, John T. Poirier, Justin F. Gainor, Ryan B. Corcoran, Jeffrey A. Engelman, Charles M. Rudin, Neal Rosen, Scott W. Lowe

    Published 2016
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  13. 13
    <i>tp53</i> mutant zebrafish develop malignant peripheral nerve sheath tumors

    <i>tp53</i> mutant zebrafish develop malignant peripheral nerve sheath tumors by Stéphane Berghmans, Ryan D. Murphey, Erno Wienholds, Donna Neuberg, Jeffery L. Kutok, Christopher D.�M. Fletcher, John P. Morris, Ting Xi Liu, Stefan Schulte‐Merker, John P. Kanki, Ronald H.A. Plasterk, Leonard I. Zon, A. Thomas Look

    Published 2005
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  14. 14
    Vitamin B6 Addiction in Acute Myeloid Leukemia

    Vitamin B6 Addiction in Acute Myeloid Leukemia by Chi-Chao Chen, Bo Li, Scott E. Millman, Cynthia Chen, Xiang Li, John P. Morris, Allison Mayle, Yu-Jui Ho, Evangelia Loizou, Hui Liu, Weige Qin, Hardik Shah, Sara Violante, Justin R. Cross, Scott W. Lowe, Lingbo Zhang

    Published 2020
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  15. 15
    The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma

    The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma by Guido von Figura, Akihisa Fukuda, Nilotpal Roy, Muluye E. Liku, John P. Morris, Grace Kim, Holger A. Russ, Matthew A. Firpo, Sean J. Mulvihill, David W. Dawson, Jorge Ferrer, William F. Mueller, Anke Busch, Klemens J. Hertel, Matthias Hebrok

    Published 2014
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  16. 16
    α-Ketoglutarate links p53 to cell fate during tumour suppression

    α-Ketoglutarate links p53 to cell fate during tumour suppression by John P. Morris, Jossie J. Yashinskie, Richard P. Koche, Rohit Chandwani, Sha Tian, Chi-Chao Chen, Timour Baslan, Zoran S. Marinkovic, Francisco J. Sánchez‐Rivera, Steven D. Leach, Carlos Carmona‐Fontaine, Craig B. Thompson, Lydia W.S. Finley, Scott W. Lowe

    Published 2019
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  17. 17
    Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

    Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling by Susann Weissmueller, Eusebio Manchado, Michael Saborowski, John P. Morris, Elvin Wagenblast, Carrie Davis, Sung‐Hwan Moon, Neil T. Pfister, Darjus F. Tschaharganeh, Thomas Kitzing, Daniela E. Aust, Elke Markert, Jianmin Wu, Sean M. Grimmond, Christian Pilarsky, Carol Prives, Andrew V. Biankin, Scott W. Lowe

    Published 2014
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  18. 18
    Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer

    Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer by Wan-Chi Lin, Nirakar Rajbhandari, Chengbao Liu, Kazuhito Sakamoto, Qian Zhang, Aleata A. Triplett, Surinder K. Batra, René Opavský, Dean W. Felsher, Dominick J. DiMaio, Michael A. Hollingsworth, John P. Morris, Matthias Hebrok, Agnieszka K. Witkiewicz, Jonathan R. Brody, Hallgeir Rui, Kay‐Uwe Wagner

    Published 2013
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  19. 19
    Metabolic adaptations direct cell fate during tissue regeneration

    Metabolic adaptations direct cell fate during tissue regeneration by Almudena Chaves Perez, Scott E. Millman, Sudha Janaki‐Raman, Yu-Jui Ho, Clemens Hinterleitner, Valentin J.A. Barthet, John P. Morris, Francisco M. Barriga, José Reyes, Aye Kyaw, H. Amalia Pasolli, Dana Pe’er, Craig B. Thompson, Lydia W.S. Finley, Justin R. Cross, Scott W. Lowe

    Published 2025
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  20. 20
    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer by Marcus Ruscetti, John P. Morris, Riccardo Mezzadra, James Russell, Josef Leibold, Paul B. Romesser, Janelle Simon, Amanda Kulick, Yu-Jui Ho, Myles Fennell, Jinyang Li, Robert J. Norgard, John E. Wilkinson, Direna Alonso‐Curbelo, Ramya Sridharan, Daniel A. Heller, Elisa de Stanchina, Ben Z. Stanger, Charles J. Sherr, Scott W. Lowe

    Published 2020
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