Ngā hua rapu kaituhi :: APM

1

Covalent drugs targeting histidine – an unexploited opportunity? mā Jianwei Che, Lyn H. Jones

I whakaputaina 2022

Whiwhi kuputuhi katoa
Editorial

Tiaki ki tētahi rārangi

I tiakina i:
2

Targeting<i>MET</i>Dysregulation in Cancer mā Gonzalo Recondo, Jianwei Che, Pasi A. Jänne, Mark M. Awad

I whakaputaina 2020

Whiwhi kuputuhi katoa
Revisão

Tiaki ki tētahi rārangi

I tiakina i:
3

Latest Trend of Milk Derived Exosomes: Cargos, Functions, and Applications mā Xin Feng, Xiaolin Chen, Xucan Zheng, Hui Zhu, Qien Qi, Shen Liu, Huihua Zhang, Jianwei Che

I whakaputaina 2021

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Revisão

Tiaki ki tētahi rārangi

I tiakina i:
4

Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library mā Chelsea E. Powell, Guangyan Du, Jianwei Che, Zhixiang He, Katherine A. Donovan, Hong Yue, Eric S. Wang, Radosław P. Nowak, Tinghu Zhang, Eric S. Fischer, Nathanael S. Gray

I whakaputaina 2020

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
5

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2 mā Guangyan Du, Jie Jiang, Qibiao Wu, Nathaniel J. Henning, Katherine A. Donovan, Hong Yue, Jianwei Che, Wenchao Lu, Eric S. Fischer, Nabeel Bardeesy, Tinghu Zhang, Nathanael S. Gray

I whakaputaina 2021

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
6

Expanding the Diversity of Allosteric Bcr-Abl Inhibitors mā Xianming Deng, Okram Barun, Qiang Ding, Jianming Zhang, Yongmun Choi, Francisco Adrián, Amy Wojciechowski, Guobao Zhang, Jianwei Che, Badry Bursulaya, Sandra W. Cowan‐Jacob, Gabriele Rummel, Taebo Sim, Nathanael S. Gray

I whakaputaina 2010

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
7

Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells mā Yang Sun, Lu Hu, Zhipeng Tao, Gopala K. Jarugumilli, Hannah Erb, Alka Singh, Qi Li, Jennifer L. Cotton, Patricia Greninger, Regina K. Egan, Y. Tony Ip, Cyril H. Benes, Jianwei Che, Junhao Mao, Xu Wu

I whakaputaina 2022

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
8

Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator mā Shifeng Pan, Nathanael S. Gray, Wenqi Gao, Yuan Mi, Yi Fan, Xing Wang, Tove Tuntland, Jianwei Che, Sophie Lefebvre, Yu Chen, Alan Chu, Klaus Hinterding, Anne Gardin, Peter End, Peter Heining, Christian Bruns, Nigel G. Cooke, Barbara Nuesslein‐Hildesheim

I whakaputaina 2013

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
9

Discovery and resistance mechanism of a selective CDK12 degrader mā Baishan Jiang, Yang Gao, Jianwei Che, Wenchao Lu, Ines H. Kaltheuner, Ruben Dries, Marian Kalocsay, Matthew J. Berberich, Jie Jiang, Inchul You, Nicholas Kwiatkowski, Kristin M. Riching, Danette L. Daniels, Peter K. Sorger, Matthias Geyer, Tinghu Zhang, Nathanael S. Gray

I whakaputaina 2021

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
10

Cereblon covalent modulation through structure-based design of histidine targeting chemical probes mā Justin T. Cruite, Geoffrey P. Dann, Jianwei Che, Katherine A. Donovan, Silas Ferrao, Scott B. Ficarro, Eric S. Fischer, Nathanael S. Gray, Fidel Huerta, Nikki R. Kong, Hu Liu, Jarrod A. Marto, Rebecca J. Metivier, Radosław P. Nowak, Breanna L. Zerfas, Lyn H. Jones

I whakaputaina 2022

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
11

Exploring the target scope of KEAP1 E3 ligase-based PROTACs mā Guangyan Du, Jie Jiang, Nathaniel J. Henning, Nozhat Safaee, Eriko Koide, Radosław P. Nowak, Katherine A. Donovan, Hojong Yoon, Inchul You, Hong Yue, Nicholas A. Eleuteri, Zhixiang He, Zhengnian Li, Hubert T. Huang, Jianwei Che, Behnam Nabet, Tinghu Zhang, Eric S. Fischer, Nathanael S. Gray

I whakaputaina 2022

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
12

Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor mā Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk‐Soo Seo, Ekaterina V. Vinogradova, Tomer M. Yaron, Evanna L. Mills, Haopeng Xiao, Kristine Senkane, Emily M. Huntsman, Jared L. Johnson, Jianwei Che, Lewis C. Cantley, Benjamin F. Cravatt, Sirano Dhe‐Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S. Gray, Edward T. Chouchani

I whakaputaina 2023

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
13

Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors mā Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y. Kim, Xijun Zhu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Stephen M. Hinshaw, Behnam Nabet, Steven M. Corsello, Nicholas Kwiatkowski, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray

I whakaputaina 2023

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
14

The human zinc-binding cysteine proteome mā Nils Burger, Melanie J. Mittenbühler, Haopeng Xiao, Sang-Hee Shin, Shelley M Wei, Erik Henze, Sebastian Schindler, Sepideh Mehravar, David M. Wood, Jonathan J. Petrocelli, Yizhi Sun, Hans‐Georg Sprenger, Pedro Latorre‐Muro, Amanda L. Smythers, Luiz H. M. Bozi, Narek Darabedian, Yingde Zhu, Hyuk‐Soo Seo, Sirano Dhe‐Paganon, Jianwei Che, Edward T. Chouchani

I whakaputaina 2024

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
15

Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC mā Gonzalo Recondo, Magda Bahcall, Liam F. Spurr, Jianwei Che, Biagio Ricciuti, Giulia C. Leonardi, Ying‐Chun Lo, Yvonne Y. Li, Giuseppe Lamberti, Tom Nguyen, Marina S.D. Milan, Deepti Venkatraman, Renato Umeton, Cloud P. Paweletz, Adem Albayrak, Andrew D. Cherniack, Kristin S. Price, Stephen R. Fairclough, Mizuki Nishino, Lynette M. Sholl, Geoffrey R. Oxnard, Pasi A. Jänne, Mark M. Awad

I whakaputaina 2020

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
16

Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling mā Mengyang Fan, Wenchao Lu, Jianwei Che, Nicholas Kwiatkowski, Yang Gao, Hyuk‐Soo Seo, Scott B. Ficarro, Prafulla C. Gokhale, Yao Liu, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Miljan Kuljanin, Wenzhi Ji, Jie Jiang, Zhixiang He, Jason Tse, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Joseph D. Mancias, Jarrod A. Marto, Sirano Dhe‐Paganon, Tinghu Zhang, Nathanael S. Gray

I whakaputaina 2022

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
17

(<i>R</i>)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors mā Ha-Soon Choi, Paul V. Rucker, Zhicheng Wang, Yi Fan, Pamela Albaugh, Greg Chopiuk, F. Gessier, Fangxian Sun, Francisco Adrián, Guoxun Liu, Tami Hood, Nanxin Li, Yong Jia, Jianwei Che, Susan McCormack, Allen Li, Jie Li, Auzon Steffy, AnneMarie Culazzo, Celine Tompkins, Van Phung, Andreas Kreusch, Min Lu, Bin Hu, Apurva Chaudhary, Mahavir Prashad, Tove Tuntland, Bo Liu, Jennifer L. Harris, H. Martin Seidel, Jon C. Loren, Valentina Molteni

I whakaputaina 2015

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
18

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development mā Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman, Nicholas A. Eleuteri, Debabrata Bhunia, SeongShick Ryu, Li Tan, Kun Shi, Hong Yue, Xiaoxi Liu, Dennis Dobrovolsky, Baishan Jiang, Jinhua Wang, Mingfeng Hao, Inchul You, Mingxing Teng, Yanke Liang, John M. Hatcher, Zhengnian Li, Theresa Manz, Brian J. Groendyke, Wanyi Hu, Yunju Nam, Sandip Sengupta, Hanna Cho, Injae Shin, Michael P. Agius, Irene M. Ghobrial, W Michelle, Jianwei Che, Sara J. Buhrlage, Taebo Sim, Nathanael S. Gray, Eric S. Fischer

I whakaputaina 2020

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
19

Imaging of <i>Plasmodium</i> Liver Stages to Drive Next-Generation Antimalarial Drug Discovery mā Stephan Meister, David Plouffe, Kelli Kuhen, Ghislain M. C. Bonamy, Tao Wu, S. Whitney Barnes, Selina Bopp, Rachel Borboa, A. Taylor Bright, Jianwei Che, Steve Cohen, Neekesh V. Dharia, Kerstin Gagaring, Montip Gettayacamin, Perry Gordon, Todd Groessl, Nobutaka Kato, Lee M, Case W. McNamara, David A. Fidock, A. S. Nagle, Tae‐gyu Nam, Wendy Richmond, Jason Roland, Matthias Rottmann, Bin Zhou, Patrick Froissard, Richard Glynne, Dominique Mazier, Jetsumon Sattabongkot, Peter G. Schultz, Tove Tuntland, John R. Walker, Yingyao Zhou, Arnab K. Chatterjee, Thierry T. Diagana, Elizabeth A. Winzeler

I whakaputaina 2011

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:
20

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 mā Jun Liu, Shifeng Pan, Mindy H. Hsieh, Nicholas Ng, Fangxian Sun, Tao Wang, Shailaja Kasibhatla, Alwin G. Schuller, Allen G. Li, Cheng Dai, Jie Li, Celin Tompkins, AnneMarie Pferdekamper, Auzon Steffy, Jane Cheng, Colleen Kowal, Van Phung, Gui-Rong Guo, Yan Wang, Martin P. Graham, Shannon Flynn, J. Chad Brenner, Chun Li, Maria Cristina Villarroel, Peter G. Schultz, Xu Wu, Peter McNamara, William R. Sellers, Lilli Petruzzelli, Anthony Boral, H. Martin Seidel, Margaret E. McLaughlin, Jianwei Che, Thomas E. Carey, Gary Vanasse, Jennifer L. Harris

I whakaputaina 2013

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i: