検索結果 - Jesse S. Boehm

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  1. 1
    Emerging Opportunities for Target Discovery in Rare Cancers

    Emerging Opportunities for Target Discovery in Rare Cancers 著者: Tanaz Sharifnia, Andrew L. Hong, Corrie Painter, Jesse S. Boehm

    出版事項 2017
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    Revisão
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  2. 2
    Transformation of Human and Murine Fibroblasts without Viral Oncoproteins

    Transformation of Human and Murine Fibroblasts without Viral Oncoproteins 著者: Jesse S. Boehm, Meghan T. Hession, Sara E. Bulmer, William C. Hahn

    出版事項 2005
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    Artigo
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  3. 3
    Global computational alignment of tumor and cell line transcriptional profiles

    Global computational alignment of tumor and cell line transcriptional profiles 著者: Allison Warren, Yejia Chen, Andrew Jones, Tsukasa Shibue, William C. Hahn, Jesse S. Boehm, Francisca Vázquez, Aviad Tsherniak, James M. McFarland

    出版事項 2021
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    Artigo
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  4. 4
    Chronos: a CRISPR cell population dynamics model

    Chronos: a CRISPR cell population dynamics model 著者: Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    出版事項 2021
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    Pré-impressão
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  5. 5
    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects 著者: Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    出版事項 2021
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    Artigo
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  6. 6
    Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects

    Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects 著者: Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark‐Anthony Bray, Federica Piccioni, David E. Root, John G. Doench, Jesse S. Boehm, Anne E. Carpenter

    出版事項 2015
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    Artigo
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  7. 7
    Systematic morphological profiling of human gene and allele function via Cell Painting

    Systematic morphological profiling of human gene and allele function via Cell Painting 著者: Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia Hicks‐Berthet, Mark‐Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S. Boehm, Anne E. Carpenter

    出版事項 2017
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    Artigo
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  8. 8
    Sparse dictionary learning recovers pleiotropy from human cell fitness screens

    Sparse dictionary learning recovers pleiotropy from human cell fitness screens 著者: Joshua Pan, Jason J. Kwon, Jessica A. Talamas, Ashir A. Borah, Francisca Vázquez, Jesse S. Boehm, Aviad Tsherniak, Marinka Žitnik, James M. McFarland, William C. Hahn

    出版事項 2022
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    Artigo
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  9. 9
    Patient-derived xenografts undergo mouse-specific tumor evolution

    Patient-derived xenografts undergo mouse-specific tumor evolution 著者: Uri Ben‐David, Gavin Ha, Yuen‐Yi Tseng, Noah F. Greenwald, Coyin Oh, Juliann Shih, James M. McFarland, Bang Wong, Jesse S. Boehm, Rameen Beroukhim, Todd R. Golub

    出版事項 2017
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    Artigo
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  10. 10
    Cell Painting predicts impact of lung cancer variants

    Cell Painting predicts impact of lung cancer variants 著者: Juan Carlos Caicedo, John Arévalo, Federica Piccioni, Mark‐Anthony Bray, Cathy L Hartland, Xiaoyun Wu, Angela N. Brooks, Alice H. Berger, Jesse S. Boehm, Anne E. Carpenter, Shantanu Singh

    出版事項 2022
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    Artigo
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  11. 11
    PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling

    PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling 著者: Susan E. Moody, Anna C. Schinzel, Sharat Singh, Francesca Izzo, Matthew R. Strickland, Leo Y. Luo, S R Thomas, Jesse S. Boehm, So Young Kim, Z C Wang, William C. Hahn

    出版事項 2014
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    Artigo
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  12. 12
    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry

    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry 著者: Amanda L. Creech, Jordan E. Taylor, Verena Maier, Xiaoyun Wu, Caitlin M. Feeney, Namrata D. Udeshi, Sally E. Peach, Jesse S. Boehm, Jeannie T. Lee, Steven A. Carr, Jacob D. Jaffe

    出版事項 2014
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    Artigo
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  13. 13
    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal 著者: John M. Krill-Burger, Joshua M. Dempster, Ashir A. Borah, Brenton R. Paolella, David E. Root, Todd R. Golub, Jesse S. Boehm, William C. Hahn, James M. McFarland, Francisca Vázquez, Aviad Tsherniak

    出版事項 2023
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    Artigo
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  14. 14
    PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

    PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling 著者: Yashaswi Shrestha, Eric J. Schafer, Jesse S. Boehm, Sapana Thomas, Frank He, Jinyan Du, Shumei Wang, Jordi Barretina, Barbara A. Weir, Jean J. Zhao, Kornélia Polyák, Todd R. Golub, Rameen Beroukhim, William C. Hahn

    出版事項 2011
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    Artigo
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  15. 15
    CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

    CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity 著者: So Young Kim, Ian F. Dunn, Ron Firestein, Piyush B. Gupta, Leslie Wardwell, Kara Repich, Anna C. Schinzel, Ben S. Wittner, Serena J. Silver, David E. Root, Jesse S. Boehm, Sridhar Ramaswamy, Eric S. Lander, William C. Hahn

    出版事項 2010
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    Artigo
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  16. 16
    Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

    Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood 著者: Julia Joung, J Engreitz, Silvana Konermann, Omar O. Abudayyeh, Vanessa K. Verdine, François Aguet, Jonathan S. Gootenberg, Neville E. Sanjana, Jason Wright, Charles P. Fulco, Yuen‐Yi Tseng, Charles H. Yoon, Jesse S. Boehm, Eric S. Lander, Feng Zhang

    出版事項 2017
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    Artigo
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  17. 17
    NetSig: network-based discovery from cancer genomes

    NetSig: network-based discovery from cancer genomes 著者: Heiko Horn, Michael S. Lawrence, Candace R. Chouinard, Yashaswi Shrestha, Jessica Xin Hu, Elizabeth Worstell, Emily Shea, Nina Ilić, Eejung Kim, Atanas Kamburov, Alireza Kashani, William C. Hahn, Joshua D. Campbell, Jesse S. Boehm, Gad Getz, Kasper Lage

    出版事項 2017
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    Artigo
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  18. 18
    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers 著者: Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel A. Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lọla Fagbami, David E. Root, Jacob D. Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

    出版事項 2016
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    Artigo
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  19. 19
    Amplification of <i>CRKL</i> Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers

    Amplification of <i>CRKL</i> Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers 著者: Hiu Wing Cheung, Jinyan Du, Jesse S. Boehm, Frank He, Barbara A. Weir, Xiaoxing Wang, Mohit Butaney, Lecia V. Sequist, Biao Luo, Jeffrey A. Engelman, David E. Root, Matthew Meyerson, Todd R. Golub, Pasi A. Jänne, William C. Hahn

    出版事項 2011
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    Artigo
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  20. 20
    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration 著者: James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan Bryan, John M. Krill-Burger, Thomas Green, Francisca Vázquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak

    出版事項 2018
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    Artigo
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