Search Results - Jesse S. Boehm

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  1. 1
    Emerging Opportunities for Target Discovery in Rare Cancers

    Emerging Opportunities for Target Discovery in Rare Cancers by Tanaz Sharifnia, Andrew L. Hong, Corrie Painter, Jesse S. Boehm

    Published 2017
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  2. 2
    Transformation of Human and Murine Fibroblasts without Viral Oncoproteins

    Transformation of Human and Murine Fibroblasts without Viral Oncoproteins by Jesse S. Boehm, Meghan T. Hession, Sara E. Bulmer, William C. Hahn

    Published 2005
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  3. 3
    Global computational alignment of tumor and cell line transcriptional profiles

    Global computational alignment of tumor and cell line transcriptional profiles by Allison Warren, Yejia Chen, Andrew Jones, Tsukasa Shibue, William C. Hahn, Jesse S. Boehm, Francisca Vázquez, Aviad Tsherniak, James M. McFarland

    Published 2021
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  4. 4
    Chronos: a CRISPR cell population dynamics model

    Chronos: a CRISPR cell population dynamics model by Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    Published 2021
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  5. 5
    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

    Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects by Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

    Published 2021
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  6. 6
    Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects

    Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects by Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark‐Anthony Bray, Federica Piccioni, David E. Root, John G. Doench, Jesse S. Boehm, Anne E. Carpenter

    Published 2015
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  7. 7
    Systematic morphological profiling of human gene and allele function via Cell Painting

    Systematic morphological profiling of human gene and allele function via Cell Painting by Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu, Julia Hicks‐Berthet, Mark‐Anthony Bray, Yashaswi Shrestha, Xaralabos Varelas, Jesse S. Boehm, Anne E. Carpenter

    Published 2017
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  8. 8
    Sparse dictionary learning recovers pleiotropy from human cell fitness screens

    Sparse dictionary learning recovers pleiotropy from human cell fitness screens by Joshua Pan, Jason J. Kwon, Jessica A. Talamas, Ashir A. Borah, Francisca Vázquez, Jesse S. Boehm, Aviad Tsherniak, Marinka Žitnik, James M. McFarland, William C. Hahn

    Published 2022
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  9. 9
    Patient-derived xenografts undergo mouse-specific tumor evolution

    Patient-derived xenografts undergo mouse-specific tumor evolution by Uri Ben‐David, Gavin Ha, Yuen‐Yi Tseng, Noah F. Greenwald, Coyin Oh, Juliann Shih, James M. McFarland, Bang Wong, Jesse S. Boehm, Rameen Beroukhim, Todd R. Golub

    Published 2017
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  10. 10
    Cell Painting predicts impact of lung cancer variants

    Cell Painting predicts impact of lung cancer variants by Juan Carlos Caicedo, John Arévalo, Federica Piccioni, Mark‐Anthony Bray, Cathy L Hartland, Xiaoyun Wu, Angela N. Brooks, Alice H. Berger, Jesse S. Boehm, Anne E. Carpenter, Shantanu Singh

    Published 2022
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  11. 11
    PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling

    PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling by Susan E. Moody, Anna C. Schinzel, Sharat Singh, Francesca Izzo, Matthew R. Strickland, Leo Y. Luo, S R Thomas, Jesse S. Boehm, So Young Kim, Z C Wang, William C. Hahn

    Published 2014
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  12. 12
    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry

    Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry by Amanda L. Creech, Jordan E. Taylor, Verena Maier, Xiaoyun Wu, Caitlin M. Feeney, Namrata D. Udeshi, Sally E. Peach, Jesse S. Boehm, Jeannie T. Lee, Steven A. Carr, Jacob D. Jaffe

    Published 2014
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  13. 13
    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

    Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal by John M. Krill-Burger, Joshua M. Dempster, Ashir A. Borah, Brenton R. Paolella, David E. Root, Todd R. Golub, Jesse S. Boehm, William C. Hahn, James M. McFarland, Francisca Vázquez, Aviad Tsherniak

    Published 2023
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  14. 14
    PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

    PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling by Yashaswi Shrestha, Eric J. Schafer, Jesse S. Boehm, Sapana Thomas, Frank He, Jinyan Du, Shumei Wang, Jordi Barretina, Barbara A. Weir, Jean J. Zhao, Kornélia Polyák, Todd R. Golub, Rameen Beroukhim, William C. Hahn

    Published 2011
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  15. 15
    CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

    CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity by So Young Kim, Ian F. Dunn, Ron Firestein, Piyush B. Gupta, Leslie Wardwell, Kara Repich, Anna C. Schinzel, Ben S. Wittner, Serena J. Silver, David E. Root, Jesse S. Boehm, Sridhar Ramaswamy, Eric S. Lander, William C. Hahn

    Published 2010
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  16. 16
    Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

    Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood by Julia Joung, J Engreitz, Silvana Konermann, Omar O. Abudayyeh, Vanessa K. Verdine, François Aguet, Jonathan S. Gootenberg, Neville E. Sanjana, Jason Wright, Charles P. Fulco, Yuen‐Yi Tseng, Charles H. Yoon, Jesse S. Boehm, Eric S. Lander, Feng Zhang

    Published 2017
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  17. 17
    NetSig: network-based discovery from cancer genomes

    NetSig: network-based discovery from cancer genomes by Heiko Horn, Michael S. Lawrence, Candace R. Chouinard, Yashaswi Shrestha, Jessica Xin Hu, Elizabeth Worstell, Emily Shea, Nina Ilić, Eejung Kim, Atanas Kamburov, Alireza Kashani, William C. Hahn, Joshua D. Campbell, Jesse S. Boehm, Gad Getz, Kasper Lage

    Published 2017
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  18. 18
    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

    Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers by Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel A. Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lọla Fagbami, David E. Root, Jacob D. Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

    Published 2016
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  19. 19
    Amplification of <i>CRKL</i> Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers

    Amplification of <i>CRKL</i> Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers by Hiu Wing Cheung, Jinyan Du, Jesse S. Boehm, Frank He, Barbara A. Weir, Xiaoxing Wang, Mohit Butaney, Lecia V. Sequist, Biao Luo, Jeffrey A. Engelman, David E. Root, Matthew Meyerson, Todd R. Golub, Pasi A. Jänne, William C. Hahn

    Published 2011
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  20. 20
    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

    Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration by James M. McFarland, Zandra V. Ho, Guillaume Kugener, Joshua M. Dempster, Phillip G. Montgomery, Jordan Bryan, John M. Krill-Burger, Thomas Green, Francisca Vázquez, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Aviad Tsherniak

    Published 2018
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