Resultados da busca - Jeffrey A. Knauf

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  1. 1
    Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

    Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer por Marcia Ryder, Ronald A. Ghossein, Julio C. Ricarte‐Filho, Jeffrey A. Knauf, James A. Fagin

    Publicado em 2008
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  2. 2
    Conditional BRAFV600E Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells

    Conditional BRAFV600E Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells por Norisato Mitsutake, Jeffrey A. Knauf, Shin Mitsutake, Cléo Otaviano Mesa, Lei Zhang, James A. Fagin

    Publicado em 2005
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  3. 3
    Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells

    Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells por Matti L. Gild, Iñigo Landa, Mabel Ryder, Ronald Ghossein, Jeffrey A. Knauf, James A. Fagin

    Publicado em 2013
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  4. 4
    Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers

    Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers por Jeffrey A. Knauf, Kathleen Luckett, Kuan-Yuan Chen, Francesca Voza, Nicholas D. Socci, Ronald Ghossein, James A. Fagin

    Publicado em 2018
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  5. 5
    Inhibitors of Raf Kinase Activity Block Growth of Thyroid Cancer Cells with <i>RET/PTC</i> or <i>BRAF</i> Mutations <i>In vitro</i> and <i>In vivo</i>

    Inhibitors of Raf Kinase Activity Block Growth of Thyroid Cancer Cells with <i>RET/PTC</i> or <i>BRAF</i> Mutations <i>In vitro</i> and <i>In vivo</i> por Bin Ouyang, Jeffrey A. Knauf, Eric P. Smith, Lei Zhang, Tim Ramsey, Naeem Yusuff, David Batt, James A. Fagin

    Publicado em 2006
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  6. 6
    Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation patterns

    Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation... por Michael Rivera, Julio C. Ricarte‐Filho, Jeffrey A. Knauf, Ashok R. Shaha, Michael Tuttle, James A. Fagin, Ronald Ghossein

    Publicado em 2010
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  7. 7
    RET/PTC-Induced Cell Growth Is Mediated in Part by Epidermal Growth Factor Receptor (EGFR) Activation: Evidence for Molecular and Functional Interactions between RET and EGFR

    RET/PTC-Induced Cell Growth Is Mediated in Part by Epidermal Growth Factor Receptor (EGFR) Activation: Evidence for Molecular and Functional Interactions between RET and EGFR por Michelle Croyle, Nagako Akeno, Jeffrey A. Knauf, Doriano Fabbro, Xu Chen, Jacqueline E. Baumgartner, Heidi A. Lane, James A. Fagin

    Publicado em 2008
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  8. 8
    Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression

    Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression por Mabel Ryder, Matti L. Gild, Tobias M. Hohl, Eric G. Pamer, Jeffrey A. Knauf, Ronald Ghossein, Johanna A. Joyce, James A. Fagin

    Publicado em 2013
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  9. 9
    Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

    Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer por Raffaele Ciampi, Jeffrey A. Knauf, Roswitha Kerler, Manoj Gandhi, Zhaowen Zhu, Marina N. Nikiforova, H. Rabes, James A. Fagin, Yuri E. Nikiforov

    Publicado em 2005
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  10. 10
    Molecular, Morphologic, and Outcome Analysis of Thyroid Carcinomas According to Degree of Extrathyroid Extension

    Molecular, Morphologic, and Outcome Analysis of Thyroid Carcinomas According to Degree of Extrathyroid Extension por Michael Rivera, Julio C. Ricarte‐Filho, R. Michael Tuttle, Ian Ganly, Ashok R. Shaha, Jeffrey A. Knauf, James A. Fagin, Ronald Ghossein

    Publicado em 2010
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  11. 11
    BRAFV600E Mutation Is Associated with Preferential Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibition in Thyroid Cancer Cell Lines

    BRAFV600E Mutation Is Associated with Preferential Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibition in Thyroid Cancer Cell Lines por Rébecca Leboeuf, Jacqueline E. Baumgartner, Miriam Benezra, Roberta Malaguarnera, David B. Solit, Christine A. Pratilas, Neal Rosen, Jeffrey A. Knauf, James A. Fagin

    Publicado em 2008
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  12. 12
    RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response

    RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response por Efisio Puxeddu, Jeffrey A. Knauf, Maureen A. Sartor, Norisato Mitsutake, Eric P. Smith, Mario Medvedovic, Craig R. Tomlinson, Sonia Moretti, James A. Fagin

    Publicado em 2005
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  13. 13
    Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

    Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling por Jeffrey A. Knauf, Maureen A. Sartor, Mario Medvedovic, Emma T. Lundsmith, Michael Ryder, Marcella Salzano, Yuri E. Nikiforov, Thomas J. Giordano, Ronald Ghossein, James A. Fagin

    Publicado em 2011
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  14. 14
    Relief of Feedback Inhibition of <i>HER3</i> Transcription by RAF and MEK Inhibitors Attenuates Their Antitumor Effects in <i>BRAF</i>-Mutant Thyroid Carcinomas

    Relief of Feedback Inhibition of <i>HER3</i> Transcription by RAF and MEK Inhibitors Attenuates Their Antitumor Effects in <i>BRAF</i>-Mutant Thyroid Carcinomas por Cristina Montero‐Conde, Sergio Ruiz‐Llorente, José Miguel Domínguez, Jeffrey A. Knauf, Agnès Viale, Eric J. Sherman, Mabel Ryder, Ronald Ghossein, Neal Rosen, James A. Fagin

    Publicado em 2013
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  15. 15
    STAT3 negatively regulates thyroid tumorigenesis

    STAT3 negatively regulates thyroid tumorigenesis por Joana Couto, Laura Daly, Ana Paula de Almeida, Jeffrey A. Knauf, James A. Fagin, Manuel Sobrinho‐Simões, Jorge Lima, Valdemar Máximo, Paula Soares, David Lyden, Jacqueline Bromberg

    Publicado em 2012
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  16. 16
    Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification

    Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification por Rebecca E. Schweppe, Joshua Klopper, Christopher Korch, Umarani Pugazhenthi, Miriam Benezra, Jeffrey A. Knauf, James A. Fagin, Laura A. Marlow, John A. Copland, Robert C. Smallridge, Bryan R. Haugen

    Publicado em 2008
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  17. 17
    Mutational Profile of Advanced Primary and Metastatic Radioactive Iodine-Refractory Thyroid Cancers Reveals Distinct Pathogenetic Roles for<i>BRAF, PIK3CA</i>, and<i>AKT1</i>

    Mutational Profile of Advanced Primary and Metastatic Radioactive Iodine-Refractory Thyroid Cancers Reveals Distinct Pathogenetic Roles for<i>BRAF, PIK3CA</i>, and<i>AKT1</i> por Julio C. Ricarte‐Filho, Mabel Ryder, Dhananjay Chitale, Michael Rivera, Adriana Heguy, Marc Ladanyi, Manickam Janakiraman, David B. Solit, Jeffrey A. Knauf, R. Michael Tuttle, Ronald Ghossein, James A. Fagin

    Publicado em 2009
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  18. 18
    BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

    BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas por Marina N. Nikiforova, Edna Teruko Kimura, Manoj Gandhi, Paul W. Biddinger, Jeffrey A. Knauf, Fulvio Basolo, Zhaowen Zhu, Riccardo Giannini, Giuliana Salvatore, Alfredo Fusco, Massimo Santoro, James A. Fagin, Yuri E. Nikiforov

    Publicado em 2003
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  19. 19
    Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers

    Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers por Brian R. Untch, Vanessa Dos Anjos, María E.R. García-Rendueles, Jeffrey A. Knauf, Gnana P. Krishnamoorthy, Mahesh Saqcena, Umesh Bhanot, Nicholas D. Socci, Alan L. Ho, Ronald Ghossein, James A. Fagin

    Publicado em 2018
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  20. 20
    Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers

    Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers por Julio C. Ricarte‐Filho, Sheng Li, María E.R. García-Rendueles, Cristina Montero‐Conde, Francesca Voza, Jeffrey A. Knauf, Adriana Heguy, Agnès Viale, Bogdanova Ti, Geraldine Thomas, Christopher E. Mason, James A. Fagin

    Publicado em 2013
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