Søgeresultater - Jeffrey A. Knauf
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Inhibitors of Raf Kinase Activity Block Growth of Thyroid Cancer Cells with <i>RET/PTC</i> or <i>BRAF</i> Mutations <i>In vitro</i> and <i>In vivo</i> af Bin Ouyang, Jeffrey A. Knauf, Eric P. Smith, Lei Zhang, Tim Ramsey, Naeem Yusuff, David Batt, James A. Fagin
Udgivet 2006Artigo -
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Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation... af Michael Rivera, Julio C. Ricarte‐Filho, Jeffrey A. Knauf, Ashok R. Shaha, Michael Tuttle, James A. Fagin, Ronald Ghossein
Udgivet 2010Artigo -
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RET/PTC-Induced Cell Growth Is Mediated in Part by Epidermal Growth Factor Receptor (EGFR) Activation: Evidence for Molecular and Functional Interactions between RET and EGFR af Michelle Croyle, Nagako Akeno, Jeffrey A. Knauf, Doriano Fabbro, Xu Chen, Jacqueline E. Baumgartner, Heidi A. Lane, James A. Fagin
Udgivet 2008Artigo -
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Genetic and Pharmacological Targeting of CSF-1/CSF-1R Inhibits Tumor-Associated Macrophages and Impairs BRAF-Induced Thyroid Cancer Progression af Mabel Ryder, Matti L. Gild, Tobias M. Hohl, Eric G. Pamer, Jeffrey A. Knauf, Ronald Ghossein, Johanna A. Joyce, James A. Fagin
Udgivet 2013Artigo -
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BRAFV600E Mutation Is Associated with Preferential Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibition in Thyroid Cancer Cell Lines af Rébecca Leboeuf, Jacqueline E. Baumgartner, Miriam Benezra, Roberta Malaguarnera, David B. Solit, Christine A. Pratilas, Neal Rosen, Jeffrey A. Knauf, James A. Fagin
Udgivet 2008Artigo -
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RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response af Efisio Puxeddu, Jeffrey A. Knauf, Maureen A. Sartor, Norisato Mitsutake, Eric P. Smith, Mario Medvedovic, Craig R. Tomlinson, Sonia Moretti, James A. Fagin
Udgivet 2005Artigo -
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Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling af Jeffrey A. Knauf, Maureen A. Sartor, Mario Medvedovic, Emma T. Lundsmith, Michael Ryder, Marcella Salzano, Yuri E. Nikiforov, Thomas J. Giordano, Ronald Ghossein, James A. Fagin
Udgivet 2011Artigo -
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Relief of Feedback Inhibition of <i>HER3</i> Transcription by RAF and MEK Inhibitors Attenuates Their Antitumor Effects in <i>BRAF</i>-Mutant Thyroid Carcinomas af Cristina Montero‐Conde, Sergio Ruiz‐Llorente, José Miguel Domínguez, Jeffrey A. Knauf, Agnès Viale, Eric J. Sherman, Mabel Ryder, Ronald Ghossein, Neal Rosen, James A. Fagin
Udgivet 2013Carta -
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Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification af Rebecca E. Schweppe, Joshua Klopper, Christopher Korch, Umarani Pugazhenthi, Miriam Benezra, Jeffrey A. Knauf, James A. Fagin, Laura A. Marlow, John A. Copland, Robert C. Smallridge, Bryan R. Haugen
Udgivet 2008Artigo -
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Mutational Profile of Advanced Primary and Metastatic Radioactive Iodine-Refractory Thyroid Cancers Reveals Distinct Pathogenetic Roles for<i>BRAF, PIK3CA</i>, and<i>AKT1</i> af Julio C. Ricarte‐Filho, Mabel Ryder, Dhananjay Chitale, Michael Rivera, Adriana Heguy, Marc Ladanyi, Manickam Janakiraman, David B. Solit, Jeffrey A. Knauf, R. Michael Tuttle, Ronald Ghossein, James A. Fagin
Udgivet 2009Artigo -
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BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas af Marina N. Nikiforova, Edna Teruko Kimura, Manoj Gandhi, Paul W. Biddinger, Jeffrey A. Knauf, Fulvio Basolo, Zhaowen Zhu, Riccardo Giannini, Giuliana Salvatore, Alfredo Fusco, Massimo Santoro, James A. Fagin, Yuri E. Nikiforov
Udgivet 2003Artigo -
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Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers af Brian R. Untch, Vanessa Dos Anjos, María E.R. García-Rendueles, Jeffrey A. Knauf, Gnana P. Krishnamoorthy, Mahesh Saqcena, Umesh Bhanot, Nicholas D. Socci, Alan L. Ho, Ronald Ghossein, James A. Fagin
Udgivet 2018Artigo -
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Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers af Julio C. Ricarte‐Filho, Sheng Li, María E.R. García-Rendueles, Cristina Montero‐Conde, Francesca Voza, Jeffrey A. Knauf, Adriana Heguy, Agnès Viale, Bogdanova Ti, Geraldine Thomas, Christopher E. Mason, James A. Fagin
Udgivet 2013Artigo
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Cancer research
Biology
Cancer
Thyroid cancer
Medicine
Internal medicine
Thyroid
Genetics
Cell biology
Gene
MAPK/ERK pathway
Signal transduction
Endocrinology
Oncology
Papillary thyroid cancer
Kinase
Mutation
Thyroid carcinoma
KRAS
Pathology
Anaplastic thyroid cancer
Carcinogenesis
HRAS
Biochemistry
Colorectal cancer
Gene expression
Receptor
Cell cycle
Cell growth
Chemistry