Ngā hua rapu kaituhi :: APM

1

Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein mā Mohammad S. Eram, Susan P. Bustos, Evelyne Lima‐Fernandes, Alena Siarheyeva, Guillermo Senisterra, Taraneh Hajian, Irene Chau, Shili Duan, Hong Wu, L. Dombrovski, Matthieu Schapira, C.H. Arrowsmith, Masoud Vedadi

I whakaputaina 2014

Whiwhi kuputuhi katoa
Artigo

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2

The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition mā Serah Kimani, Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li, Pegah Ghiabi, Yanjun Li, Irene Chau, C.H. Arrowsmith, Dalia Baršytė-Lovejoy, Vijayaratnam Santhakumar, Masoud Vedadi, Levon Halabelian

I whakaputaina 2023

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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3

SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses mā Fengling Li, Pegah Ghiabi, Taraneh Hajian, Martin Klíma, Alice Shi Ming Li, Aliakbar Khalili Yazdi, Irene Chau, P. Loppnau, Maria Kutera, Almagul Seitova, Albina Bolotokova, Ashley Hutchinson, Sumera Perveen, Evžen Bouřa, Masoud Vedadi

I whakaputaina 2023

Whiwhi kuputuhi katoa
Artigo

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4

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium mā Amy K. Wernimont, J.D. Artz, P.J. Finerty, Yu‐Hui Lin, Mehrnaz Amani, Abdellah Allali‐Hassani, Guillermo Senisterra, Masoud Vedadi, W. Tempel, Farrell MacKenzie, Irene Chau, Sebastian Lourido, L. David Sibley, Raymond Hui

I whakaputaina 2010

Whiwhi kuputuhi katoa
Artigo

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5

Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain mā Guillermo Senisterra, Hugh Zhu, Xiao Luo, Hailong Zhang, Guoliang Xun, Chunliang Lu, Wen Xiao, Taraneh Hajian, P. Loppnau, Irene Chau, Fengling Li, Abdellah Allali‐Hassani, Peter Atadja, Counde O-Yang, En Li, Peter J. Brown, C.H. Arrowsmith, Kehao Zhao, Zhengtian Yu, Masoud Vedadi

I whakaputaina 2018

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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6

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors mā Kanchan Devkota, Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau, Pegah Ghiabi, Taraneh Hajian, P. Loppnau, Albina Bolotokova, K.J.F. Satchell, Ke Wang, Deyao Li, Jing Liu, David Smil, Minkui Luo, Jian Jin, Paul V. Fish, Peter J. Brown, Masoud Vedadi

I whakaputaina 2021

Whiwhi kuputuhi katoa
Artigo

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7

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a mā Feng Liu, Xin Chen, Abdellah Allali‐Hassani, Amy Quinn, Gregory A. Wasney, Aiping Dong, Dalia Barsyte, I. Kozieradzki, Guillermo Senisterra, Irene Chau, Alena Siarheyeva, Dmitri Kireev, Ajit Jadhav, J. Martin Herold, Stephen V. Frye, C.H. Arrowsmith, Peter J. Brown, Anton Simeonov, Masoud Vedadi, Jian Jin

I whakaputaina 2009

Whiwhi kuputuhi katoa
Artigo

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8

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 mā Guillermo Senisterra, Hong Wu, Abdellah Allali‐Hassani, Gregory A. Wasney, Dalia Baršytė-Lovejoy, L. Dombrovski, Aiping Dong, Kong T. Nguyen, David Smil, Yuri Bolshan, Taraneh Hajian, Hao He, Alma Seitova, Irene Chau, Fengling Li, Gennadiy Poda, Jean‐François Couture, Peter J. Brown, Rima Al‐awar, Matthieu Schapira, C.H. Arrowsmith, Masoud Vedadi

I whakaputaina 2012

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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9

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines. mā Feng Liu, Xin Chen, Abdellah Allali‐Hassani, Amy Quinn, Tim J. Wigle, Gregory A. Wasney, Aiping Dong, Guillermo Senisterra, Irene Chau, Alena Siarheyeva, Jacqueline L. Norris, Dmitri Kireev, Ajit Jadhav, J. Martin Herold, William P. Janzen, C.H. Arrowsmith, Stephen V. Frye, Peter J. Brown, Anton Simeonov, Masoud Vedadi, Jian Jin

I whakaputaina 2010

Whiwhi kuputuhi katoa
Artigo

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10

An Allosteric Inhibitor of Protein Arginine Methyltransferase 3 mā Alena Siarheyeva, Guillermo Senisterra, Abdellah Allali‐Hassani, Aiping Dong, E. Dobrovetsky, Gregory A. Wasney, Irene Chau, Richard Marcellus, Taraneh Hajian, Feng Liu, Ilia Korboukh, David Smil, Yuri Bolshan, Jinrong Min, Hong Wu, Hong Zeng, P. Loppnau, Gennadiy Poda, Carly Griffin, Ahmed Aman, Peter J. Brown, Jian Jin, Rima Al‐awar, C.H. Arrowsmith, Matthieu Schapira, Masoud Vedadi

I whakaputaina 2012

Whiwhi kuputuhi katoa
Artigo

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11

Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase mā Isha Singh, Fengling Li, Elissa A. Fink, Irene Chau, Alice Shi Ming Li, Annia Rodríguez‐Hernández, Isabella Glenn, Francisco J. Zapatero‐Belinchón, Myosotys Rodriguez, Kanchan Devkota, Zhijie Deng, Kris M. White, Xiaobo Wan, Nataliya A. Tolmachova, Yurii S. Moroz, H. Ümit Kanıskan, Mélanie Ott, Adolfo Garcı́a-Sastre, Jian Jin, Danica Galonić Fujimori, John J. Irwin, Masoud Vedadi, Brian K. Shoichet

I whakaputaina 2023

Whiwhi kuputuhi katoa
Artigo

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12

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function mā Vincent Fagan, C. Johansson, C. Gileadi, Octovia Monteiro, James E. Dunford, Reshma Nibhani, Martin Philpott, Jessica Malzahn, Graham Wells, Ruth Faram, Adam P. Cribbs, Nadia Halidi, Fengling Li, Irene Chau, Holger Greschik, Srikannathasan Velupillai, Abdellah Allali‐Hassani, James M. Bennett, Thomas Christott, Charline Giroud, Andrew M. Lewis, K. Huber, Nick Athanasou, C. Bountra, Manfred Jung, Roland Schüle, Masoud Vedadi, C.H. Arrowsmith, Yan Xiong, Jian Jin, Oleg Fedorov, Gillian Farnie, Paul E. Brennan, Udo Oppermann

I whakaputaina 2019

Whiwhi kuputuhi katoa
Artigo

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13

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells mā Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu, Sylvie Rival‐Gervier, Abdellah Allali‐Hassani, Viviane Labrie, Tim J. Wigle, Peter A. DiMaggio, Gregory A. Wasney, Alena Siarheyeva, Aiping Dong, W. Tempel, Sun-Chong Wang, Xin Chen, Irene Chau, Thomas J Mangano, Xi‐Ping Huang, Catherine Simpson, Samantha G Pattenden, Jacqueline L Norris, Dmitri Kireev, Ashutosh Tripathy, A.M. Edwards, Bryan L. Roth, William P Janzen, Benjamin A. García, Artūras Petronis, James Ellis, Peter J. Brown, Stephen V. Frye, C.H. Arrowsmith, Jian Jin

I whakaputaina 2011

Whiwhi kuputuhi katoa
Artigo

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14

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization mā David Dilworth, Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta, Matthew R. Marunde, Suzanne Ackloo, Raquel A. C. Machado, Aliakbar Khalili Yazdi, Dominic D. G. Owens, Victoria Vu, Yan Nie, Mona Alqazzaz, Edyta Marcon, Fengling Li, Irene Chau, Albina Bolotokova, Qin Su, Ming Lei, Yanli Liu, Magdalena M. Szewczyk, Aiping Dong, Sina Kazemzadeh, Tigran M. Abramyan, Irina K. Popova, Nathan W Hall, Matthew J. Meiners, Marcus A. Cheek, Elisa Gibson, Dmitri Kireev, Jack Greenblatt, Michael‐Christopher Keogh, Jinrong Min, Peter J. Brown, Masoud Vedadi, C.H. Arrowsmith, Dalia Baršytė-Lovejoy, Lindsey I. James, Matthieu Schapira

I whakaputaina 2021

Whiwhi kuputuhi katoa
Artigo

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15

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein mā Fengling Li, Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck, Jan Beránek, Francois Berenger, Albina Bolotokova, Guillaume Bret, Marko Breznik, Emanuele Carosati, Irene Chau, Yu Chen, Artem Cherkasov, Dennis Della Corte, Katrin Denzinger, A. Dong, Sorin Draga, Ian Dunn, Kristina Edfeldt, A.M. Edwards, Merveille Eguida, Paul Eisenhuth, Lukas Friedrich, Alexander Fürll, Spencer Gardiner, Francesco Gentile, Pegah Ghiabi, Elisa Gibson, Marta Glavatskikh, Christoph Gorgulla, Judith Günther, Anders Gunnarsson, Filipp Gusev, Evgeny Gutkin, Levon Halabelian, Rachel Harding, Alexander Hillisch, Laurent Hoffer, Anders Hogner, Scott Houliston, John J. Irwin, Olexandr Isayev, Aleksandra Ivanová, Célien Jacquemard, Austin J. Jarrett, Jan H. Jensen, Dmitri Kireev, Julian M. Kleber, S. Benjamin Koby, David Ryan Koes, Ashutosh Kumar, Maria Kurnikova, Alina Kutlushina, Uta Lessel, Fabian Ließmann, Sijie Liu, Wei Lu, Jens Meiler, Akhila Mettu, Guzel Minibaeva, Rocco Moretti, Connor J. Morris, Chamali Narangoda, Theresa Noonan, Leon Obendorf, Szymon Pach, Amit Pandit, Sumera Perveen, Gennady Poda, Pavel Polishchuk, Kristina Puls, Vera Pütter, Didier Rognan, Dylan Roskams-Edris, Christina Schindler, François Sindt, Vojtěch Spiwok, Casper Steinmann, Rick Stevens, Valerij Talagayev, Damon Tingey, Oanh Vu, W. Patrick Walters, Xiaowen Wang, Zhenyu Wang, Gerhard Wolber, Clemens Alexander Wolf, Lars Wortmann, Hong Zeng, Carlos Zepeda, Kam Y. J. Zhang, Jixian Zhang, Shuangjia Zheng, Matthieu Schapira

I whakaputaina 2024

Whiwhi kuputuhi katoa
Artigo

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