Bilaketaren emaitzak - Ignaty Leshchiner

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  1. 1
    Comprehensive assessment of cancer missense mutation clustering in protein structures

    Comprehensive assessment of cancer missense mutation clustering in protein structures nork Atanas Kamburov, Michael S. Lawrence, Paz Polak, Ignaty Leshchiner, Kasper Lage, Todd R. Golub, Eric S. Lander, Gad Getz

    Argitaratua 2015
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  2. 2
    Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish

    Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish nork Sean O. Ryan, Jason R. Willer, Lindsay Marjoram, Jennifer Bagwell, Jamie L. Mankiewicz, Ignaty Leshchiner, Wolfram Goessling, Michel Bagnat, Nicholas Katsanis

    Argitaratua 2013
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  3. 3
    Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

    Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery nork Kerry P. Mahon, Kevin T. Love, Kathryn A. Whitehead, June Qin, Akin Akinc, Elizaveta S. Leshchiner, Ignaty Leshchiner, Róbert Langer, Daniel G. Anderson

    Argitaratua 2010
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  4. 4
    Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

    Tfap2a is a novel gatekeeper of nephron differentiation during kidney development nork Brooke E. Chambers, Gary F. Gerlach, Eleanor G. Clark, Karen H. Chen, Anna E. Levesque, Ignaty Leshchiner, Wolfram Goessling, Rebecca A. Wingert

    Argitaratua 2019
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  5. 5
    Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

    Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair nork Nicholas J. Haradhvala, Jaegil Kim, Yosef E. Maruvka, Paz Polak, Daniel Rosebrock, Dimitri Livitz, Julian M. Hess, Ignaty Leshchiner, Atanas Kamburov, Kent W. Mouw, Mike S. Lawrence, Gad Getz

    Argitaratua 2018
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  6. 6
    Inferring early genetic progression in cancers with unobtainable premalignant disease

    Inferring early genetic progression in cancers with unobtainable premalignant disease nork Ignaty Leshchiner, Edmund A. Mroz, Justin Cha, Daniel Rosebrock, Oliver Spiro, Juliana Bonilla‐Velez, William C. Faquin, Armida Lefranc-Torres, Derrick T. Lin, William A. Michaud, Gad Getz, James W. Rocco

    Argitaratua 2023
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  7. 7
    FireCloud, a scalable cloud-based platform for collaborative genome analysis: Strategies for reducing and controlling costs

    FireCloud, a scalable cloud-based platform for collaborative genome analysis: Strategies for reducing and controlling costs nork Chet Birger, Megan Hanna, Edward A. Salinas, Jason C. Neff, Gordon Saksena, Dimitri Livitz, Daniel Rosebrock, Chip Stewart, Ignaty Leshchiner, Alexander Baumann, Douglas Voet, Kristian Cibulskis, Eric Banks, Anthony Philippakis, Gad Getz

    Argitaratua 2017
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  8. 8
    Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia

    Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia nork Ishwarya Murali, Siddha Kasar, Aishath Naeem, Svitlana Tyekucheva, Jasneet Kaur Khalsa, Emily M. Thrash, Gilad Itchaki, Dimitri Livitz, Ignaty Leshchiner, Shuai Dong, Stacey M. Fernandes, Gad Getz, Amy J. Johnson, Jennifer R. Brown

    Argitaratua 2021
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  9. 9
    Mutation mapping and identification by whole-genome sequencing

    Mutation mapping and identification by whole-genome sequencing nork Ignaty Leshchiner, Kristen Alexa, Peter B. Kelsey, Ivan Adzhubei, Christina Austin‐Tse, Jeffrey D. Cooney, Heidi Anderson, Matthew J. King, Rolf W. Stottmann, Maija Garnaas, Seungshin Ha, Iain A. Drummond, Barry H. Paw, Trista E. North, David R. Beier, Wolfram Goessling, Shamil Sunyaev

    Argitaratua 2012
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  10. 10
    The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development

    The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development nork Paul Kroeger, Bridgette E. Drummond, Rachel Miceli, Michael McKernan, Gary F. Gerlach, Amanda N. Marra, Annemarie Fox, Kristen K. McCampbell, Ignaty Leshchiner, Adriana Rodrı́guez-Marı́, Ruth Bremiller, Ryan Thummel, Alan J. Davidson, John H. Postlethwait, Wolfram Goessling, Rebecca A. Wingert

    Argitaratua 2017
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  11. 11
    Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors

    Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors nork Aishath Naeem, Liang Li, Filippo Utro, Justin Cha, Junko Tsuji, Stacey M. Fernandes, Roberta Santos Azevedo, Francesca Morelli, Zunqiu Wang, Samantha J. Shupe, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Alexandria Kluge, Matthew S. Davids, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

    Argitaratua 2023
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  12. 12
    The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy

    The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy nork Dan A. Landau, Clare Sun, Daniel Rosebrock, Sarah E. M. Herman, Joshua Fein, Mariela Sivina, Chingiz Underbayev, Delong Liu, Julia Hoellenriegel, Sarangan Ravichandran, Mohammed Farooqui, Wandi Zhang, Carrie Cibulskis, Asaf Zviran, Donna Neuberg, Dimitri Livitz, Ivana Božić, Ignaty Leshchiner, Gad Getz, Jan A. Burger, Adrian Wiestner, Catherine J. Wu

    Argitaratua 2017
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  13. 13
    Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History

    Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History nork Livius Penter, Satyen H. Gohil, Caleb A. Lareau, Leif S. Ludwig, Erin M. Parry, Teddy Huang, Shuqiang Li, Wandi Zhang, Dimitri Livitz, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Laura Z. Rassenti, Thomas J. Kipps, Jennifer R. Brown, Matthew S. Davids, Donna Neuberg, Kenneth J. Livak, Vijay G. Sankaran, Catherine J. Wu

    Argitaratua 2021
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  14. 14
    Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

    Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment nork Ignaty Leshchiner, Dimitri Livitz, Justin F. Gainor, Daniel Rosebrock, Oliver Spiro, Aina Zurita Martinez, Edmund A. Mroz, W. Marston Linehan, Chip Stewart, Seungchan Kim, Liudmila Elagina, Ivana Božić, Mari Mino‐Kenudson, Marguerite Rooney, Sai‐Hong Ignatius Ou, Catherine J. Wu, James W. Rocco, Jeffrey A. Engelman, Alice T. Shaw, Gad Getz

    Argitaratua 2018
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  15. 15
    Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer

    Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer nork James T. Coates, Sheng Sun, Ignaty Leshchiner, Nayana Thimmiah, Elizabeth E. Martin, Daniel E. McLoughlin, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Elyssa N. Denault, Charlotte S. Walmsley, Avinash Kambadakone, James R. Stone, Steven J. Isakoff, Laxmi Parida, Dejan Juric, Gad Getz, Aditya Bardia, Leif W. Ellisen

    Argitaratua 2021
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  16. 16
    Paired exome analysis of Barrett's esophagus and adenocarcinoma

    Paired exome analysis of Barrett's esophagus and adenocarcinoma nork Matthew D. Stachler, Amaro Taylor‐Weiner, Shouyong Peng, Aaron McKenna, Agoston T. Agoston, Robert D. Odze, Jon M. Davison, Katie S. Nason, Massimo Loda, Ignaty Leshchiner, Chip Stewart, Petar Stojanov, Sara Seepo, Michael S. Lawrence, Daysha Ferrer-Torres, Jules Lin, Andrew C. Chang, Stacey Gabriel, Eric S. Lander, David G. Beer, Gad Getz, Scott L. Carter, Adam J. Bass

    Argitaratua 2015
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  17. 17
    Resensitization to Crizotinib by the Lorlatinib<i>ALK</i>Resistance Mutation L1198F

    Resensitization to Crizotinib by the Lorlatinib<i>ALK</i>Resistance Mutation L1198F nork Alice T. Shaw, Luc Friboulet, Ignaty Leshchiner, Justin F. Gainor, Simon Bergqvist, Alexei Brooun, Benjamin J. Burke, Ya‐Li Deng, Wei Liu, Leila Dardaei, Rosa L. Frias, Kate R. Schultz, Jennifer Logan, Leonard P. James, Tod Smeal, Sergei Timofeevski, Ryohei Katayama, A. John Iafrate, Long P. Le, Michele McTigue, Gad Getz, Ted W. Johnson, Jeffrey A. Engelman

    Argitaratua 2015
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  18. 18
    Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

    Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance nork Aishath Naeem, Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P. Martindale, Yinglu Zhou, Yue Ren, Svitlana Tyekucheva, Annette S. Kim, Stacey M. Fernandes, Gordon Saksena, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Matthew S. Davids, James A. Lederer, Rula Zain, Smith Rjh, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown

    Argitaratua 2022
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  19. 19
    Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors

    Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors nork Risa Burr, Ignaty Leshchiner, Christina L. Costantino, Martin Blohmer, Tilak Sundaresan, Justin Cha, Karsen Seeger, Sara Y. Guay, Brian P. Danysh, Ira Gore, Raquel A. Jacobs, Kara Slowik, Filippo Utro, Kahn Rhrissorrakrai, Chaya Levovitz, Jaimie L. Barth, Taronish D. Dubash, Brian Chirn, Laxmi Parida, Lecia V. Sequist, Jochen K. Lennerz, Mari Mino‐Kenudson, Shyamala Maheswaran, Kamila Naxerova, Gad Getz, Daniel A. Haber

    Argitaratua 2024
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  20. 20
    Growth dynamics in naturally progressing chronic lymphocytic leukaemia

    Growth dynamics in naturally progressing chronic lymphocytic leukaemia nork Michaela Gruber, Ivana Božić, Ignaty Leshchiner, Dimitri Livitz, Kristen E. Stevenson, Laura Z. Rassenti, Daniel Rosebrock, Amaro Taylor‐Weiner, Oriol Olive, Reaha Goyetche, Stacey M. Fernandes, Jing Sun, Chip Stewart, Alicia Wong, Carrie Cibulskis, Wandi Zhang, Johannes G. Reiter, Jeffrey M. Gerold, John G. Gribben, R. Kanti, Michael J. Keating, Jennifer R. Brown, Donna Neuberg, Thomas J. Kipps, Martin A. Nowak, Gad Getz, Catherine J. Wu

    Argitaratua 2019
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