Sökresultat - Hongzhi Miao

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  1. 1
    Four Hydrophobic Amino Acids of the Factor VIII C2 Domain Are Constituents of Both the Membrane-binding and von Willebrand Factor-binding Motifs

    Four Hydrophobic Amino Acids of the Factor VIII C2 Domain Are Constituents of Both the Membrane-binding and von Willebrand Factor-binding Motifs av Gary E. Gilbert, Randal J. Kaufman, Andrew A. Arena, Hongzhi Miao, Steven W. Pipe

    Publicerad 2002
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  2. 2
    Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

    Antioxidants reduce endoplasmic reticulum stress and improve protein secretion av Jyoti Malhotra, Hongzhi Miao, Kezhong Zhang, Anna R. Wolfson, Subramaniam Pennathur, Steven W. Pipe, Randal J. Kaufman

    Publicerad 2008
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  3. 3
    SRA Gene Knockout Protects against Diet-induced Obesity and Improves Glucose Tolerance

    SRA Gene Knockout Protects against Diet-induced Obesity and Improves Glucose Tolerance av Shannon Liu, Liang Sheng, Hongzhi Miao, Thomas L. Saunders, Ormond A. MacDougald, Ronald J. Koenig, Bin Xu

    Publicerad 2014
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  4. 4
    Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma

    Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma av Katarzyna Kempińska, Bhavna Malik, Dmitry Borkin, Szymon Kłossowski, Shirish Shukla, Hongzhi Miao, Jingya Wang, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2017
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  5. 5
    NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis

    NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis av Jing Yao, Li Zhao, Qixiang Zhao, Yan Zhao, Yang Sun, Youyu Zhang, Hongzhi Miao, Q-D You, Rong Hu, Q-L Guo

    Publicerad 2014
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  6. 6
    C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis

    C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis av Cailin Collins, Jingya Wang, Hongzhi Miao, Joel C. Bronstein, Humaira Nawer, Tao Xu, María E. Figueroa, Andrew G. Muntean, Jay L. Hess

    Publicerad 2014
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  7. 7
    Multiple Roles for the Non-Coding RNA SRA in Regulation of Adipogenesis and Insulin Sensitivity

    Multiple Roles for the Non-Coding RNA SRA in Regulation of Adipogenesis and Insulin Sensitivity av Bin Xu, Isabelle Gerin, Hongzhi Miao, Dang Vu‐Phan, Craig Johnson, Ruichuan Xu, Xiaowei Chen, William P. Cawthorn, Ormond A. MacDougald, Ronald J. Koenig

    Publicerad 2010
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  8. 8
    Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein–Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)

    Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein–Protein Interaction between Menin and Mixed Lineage Leukemia (MLL) av Dmitry Borkin, Jonathan Pollock, Katarzyna Kempińska, Trupta Purohit, Xiaoqin Li, Bo Wen, Ting Zhao, Hongzhi Miao, Shirish Shukla, Miao He, Duxin Sun, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2016
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  9. 9
    Complexity of Blocking Bivalent Protein–Protein Interactions: Development of a Highly Potent Inhibitor of the Menin–Mixed-Lineage Leukemia Interaction

    Complexity of Blocking Bivalent Protein–Protein Interactions: Development of a Highly Potent Inhibitor of the Menin–Mixed-Lineage Leukemia Interaction av Dmitry Borkin, Szymon Kłossowski, Jonathan Pollock, Hongzhi Miao, Brian M. Linhares, Katarzyna Kempińska, Zhuang Jin, Trupta Purohit, Bo Wen, Miao He, Duxin Sun, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2018
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  10. 10
    The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

    The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis av Kezhong Zhang, Shiyu Wang, Jyoti Malhotra, Justin Hassler, Sung Hoon Back, Guohui Wang, Lin Chang, Wenbo Xu, Hongzhi Miao, Roberta Leonardi, Y. Eugene Chen, Suzanne Jackowski, Randal J. Kaufman

    Publicerad 2011
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  11. 11
    In vivo efficacy of platelet-delivered, high specific activity factor VIII variants

    In vivo efficacy of platelet-delivered, high specific activity factor VIII variants av Teshell K. Greene, Cheng Wang, Jessica Hirsch, Li Zhai, Jamie Gewirtz, Michael A. Thornton, Hongzhi Miao, Steven W. Pipe, Randal J. Kaufman, Rodney M. Camire, Valder R. Arruda, M. Anna Kowalska, Mortimer Poncz

    Publicerad 2010
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  12. 12
    Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

    Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner av Shihan He, B. S. Malik, Dmitry Borkin, Hongzhi Miao, Sudhanshu Shukla, Katarzyna Kempińska, Tanaya A. Purohit, Jingya Wang, L Chen, Brian Parkin, Sami N. Malek, Gwenn Danet-Desnoyers, Andrew G. Muntean, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2015
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  13. 13
    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

    Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia av Xue Qing David Wang, Dandan Fan, Qinyu Han, Yiman Liu, Hongzhi Miao, Xinyu Wang, Qinglan Li, Dong Chen, Haley Gore, Pamela Himadewi, Gerd P. Pfeifer, Tomasz Cierpicki, Jolanta Grembecka, Jianzhong Su, Shasha Chong, Liling Wan, Xiaotian Zhang

    Publicerad 2022
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  14. 14
    HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

    HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis av Yuqing Sun, Bo Zhou, Fengbiao Mao, Jing Xu, Hongzhi Miao, Zhenhua Zou, Le Tran Phuc Khoa, Younghoon Jang, Sheng F. Cai, Matthew D. Witkin, Richard P. Koche, Kai Ge, Gregory R. Dressler, Ross L. Levine, Scott A. Armstrong, Yali Dou, Jay L. Hess

    Publicerad 2018
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  15. 15
    UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

    UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators av D. Thomas Rutkowski, Jun Wu, Sung-Hoon Back, Michael U. Callaghan, Sean P. Ferris, Jahangir Iqbal, Robert L. Clark, Hongzhi Miao, Justin Hassler, Jamie L. Fornek, Michael G. Katze, M. Mahmood Hussain, Benbo Song, Jayanth Swathirajan, Junying Wang, Grace D.-Y. Yau, Randal J. Kaufman

    Publicerad 2008
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  16. 16
    Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo

    Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo av Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempińska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang, Bo Wen, Hongliang Zong, Morgan Jones, Gwenn Danet-Desnoyers, Mónica L. Guzmán, Moshe Talpaz, Dale L. Bixby, Duxin Sun, Jay L. Hess, Andrew G. Muntean, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2015
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  17. 17
    Covalent inhibition of NSD1 histone methyltransferase

    Covalent inhibition of NSD1 histone methyltransferase av Huang Huang, Christina A. Howard, Sergei Zari, Hyo Je Cho, Shirish Shukla, Hao Li, Juliano Ndoj, Paula Gónzález-Alonso, Caroline Nikolaidis, Joshua M. Abbott, David Rogawski, Mykhaylo A. Potopnyk, Katarzyna Kempińska, Hongzhi Miao, Trupta Purohit, Andrew J. Henderson, Anna K. Mapp, Maria Luisa Sulis, Adolfo A. Ferrando, Jolanta Grembecka, Tomasz Cierpicki

    Publicerad 2020
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  18. 18
    Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

    Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain av Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L. Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula Gónzález-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, Eungi Kim, Xiaotian Zhang, Joshua M. Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J.H. Ryan, Mónica L. Guzmán, Jolanta Grembecka, Tomasz Cierpicki

    Publicerad 2021
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  19. 19
    Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

    Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity av David Rogawski, Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit, Jiho Song, Jennifer Chase, Shuangjiang Li, Juliano Ndoj, Szymon Kłossowski, Eungi Kim, Fengbiao Mao, Bo Zhou, James Ropa, Marta Z. Krotoska, Zhuang Jin, Patricia Ernst, Xiaomin Feng, Gang Huang, Kenichi Nishioka, Samantha Kelly, Miao He, Bo Wen, Duxin Sun, Andrew G. Muntean, Yali Dou, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2021
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  20. 20
    Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

    Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia av Szymon Kłossowski, Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, EunGi Kim, Brian M. Linhares, Dong Chen, Gloria Jih, Eric Perkey, Huang Huang, Miao He, Bo Wen, Yì Wáng, Ke Yu, Stanley Chun-Wei Lee, Gwenn Danet-Desnoyers, Winifred Trotman, Malathi Kandarpa, Anitria Cotton, Omar Abdel‐Wahab, Hongwei Lei, Yali Dou, Mónica L. Guzmán, Luke F. Peterson, Tanja A. Grüber, Sarah M. Choi, Duxin Sun, Pingda Ren, Lian‐Sheng Li, Yi Liu, Francis Burrows, Ivan Maillard, Tomasz Cierpicki, Jolanta Grembecka

    Publicerad 2019
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