Zoekresultaten - Hans‐Ulrich Demuth

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  1. 1
    Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylproline <i>p</i>-nitroanilide in T-lymphocytes

    Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylproline <i>p</i>-nitroanilide in T-lymphocytes door E Schön, Hans‐Ulrich Demuth, A. Barth, S Ansorge

    Gepubliceerd in 1984
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  2. 2
    Alternative pathways for production of β-amyloid peptides of Alzheimer's disease

    Alternative pathways for production of β-amyloid peptides of Alzheimer's disease door Vivian Hook, Israël Schechter, Hans‐Ulrich Demuth, Gregory Hook

    Gepubliceerd in 2008
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  3. 3
    Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions

    Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions door Stephan Schilling, Torsten Hoffmann, Susanne Manhart, Matthias Hoffmann, Hans‐Ulrich Demuth

    Gepubliceerd in 2004
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  4. 4
    Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Phenotype in 5XFAD Mice

    Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Ph... door Sadim Jawhar, Oliver Wirths, Stephan Schilling, Sigrid Graubner, Hans‐Ulrich Demuth, Thomas A. Bayer

    Gepubliceerd in 2010
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  5. 5
    Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

    Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model door Oliver Wirths, Henning Breyhan, Holger Cynis, Stephan Schilling, Hans‐Ulrich Demuth, Thomas A. Bayer

    Gepubliceerd in 2009
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  6. 6
    Modulation of inositol 1,4,5‐triphosphate concentration by prolyl endopeptidase inhibition

    Modulation of inositol 1,4,5‐triphosphate concentration by prolyl endopeptidase inhibition door Ingo Schulz, Bernd Gerhartz, Antje Neubauer, Andreas Holloschi, Ulrich Heiser, Mathias Hafner, Hans‐Ulrich Demuth

    Gepubliceerd in 2002
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  7. 7
    Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study

    Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study door Jeffrey L. Frost, Bin Liu, Martin Kleinschmidt, Stephan Schilling, Hans‐Ulrich Demuth, Cynthia A. Lemere

    Gepubliceerd in 2012
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  8. 8
    Long-Term Treatment With Dipeptidyl Peptidase IV Inhibitor Improves Hepatic and Peripheral Insulin Sensitivity in the VDF Zucker Rat

    Long-Term Treatment With Dipeptidyl Peptidase IV Inhibitor Improves Hepatic and Peripheral Insulin Sensitivity in the VDF Zucker Rat door J. Andrew Pospisilik, Sara Stafford, Hans‐Ulrich Demuth, Christopher H.S. McIntosh, Raymond A. Pederson

    Gepubliceerd in 2002
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  9. 9
    Natural Products from Microalgae with Potential against Alzheimer’s Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors

    Natural Products from Microalgae with Potential against Alzheimer’s Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors door Stephanie Hielscher-Michael, Carola Griehl, Mirko Buchholz, Hans‐Ulrich Demuth, Norbert Arnold, Ludger A. Wessjohann

    Gepubliceerd in 2016
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  10. 10
    Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry

    Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption... door Robert P. Pauly, Fred Rosche, Michael Wermann, Christopher H.S. McIntosh, Raymond A. Pederson, Hans‐Ulrich Demuth

    Gepubliceerd in 1996
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  11. 11
    Dipeptidyl Peptidase IV-Resistant [<scp>d</scp>-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats

    Dipeptidyl Peptidase IV-Resistant [<scp>d</scp>-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats door Simon A. Hinke, Richard W. Gelling, Raymond A. Pederson, Susanne Manhart, Cuilan Nian, Hans‐Ulrich Demuth, Christopher H.S. McIntosh

    Gepubliceerd in 2002
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  12. 12
    Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion

    Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion door Ingo Schulz, Ulrike Zeitschel, Thomas Rudolph, David Ruiz‐Carrillo, Jens‐Ulrich Rahfeld, Bernd Gerhartz, Volker Bigl, Hans‐Ulrich Demuth, Steffen Roßner

    Gepubliceerd in 2005
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  13. 13
    The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

    The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism door Michael H. Engel, Torsten Hoffmann, Leona Wagner, Michael Wermann, Ulrich Heiser, R. Kiefersauer, Robert Huber, Wolfram Bode, Hans‐Ulrich Demuth, Hans Brandstetter

    Gepubliceerd in 2003
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  14. 14
    Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

    Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor door C. Parthier, Martin Kleinschmidt, Piotr Neumann, Rainer Rudolph, Susanne Manhart, Dagmar Schlenzig, Jörg Fanghänel, Jens‐Ulrich Rahfeld, Hans‐Ulrich Demuth, Milton T. Stubbs

    Gepubliceerd in 2007
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  15. 15
    Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase

    Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activat... door Jan A. Ehses, Vanbric R. Casilla, Tim Doty, J. Andrew Pospisilik, Kyle D. Winter, Hans‐Ulrich Demuth, Raymond A. Pederson, Christopher H.S. McIntosh

    Gepubliceerd in 2003
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  16. 16
    Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon

    Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon door Simon A. Hinke, J. Andrew Pospisilik, Hans-Ulrich Demuth, Susanne Mannhart, Kerstin Kühn‐Wache, Torsten Hoffmann, Erica Nishimura, Raymond A. Pederson, Christopher H.S. McIntosh

    Gepubliceerd in 2000
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  17. 17
    Regulation of Expression and Function of Dipeptidyl Peptidase 4 (DP4), DP8/9, and DP10 in Allergic Responses of the Lung in Rats

    Regulation of Expression and Function of Dipeptidyl Peptidase 4 (DP4), DP8/9, and DP10 in Allergic Responses of the Lung in Rats door J Schade, Michael Stephan, Andreas Schmiedl, Leona Wagner, André J. Niestroj, Hans‐Ulrich Demuth, Nadine Frerker, Christian Klemann, Kerstin Raber, Reinhard Pabst, Stephan von Hörsten

    Gepubliceerd in 2007
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  18. 18
    Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease

    Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease door Markus Morawski, Stephan Schilling, Moritz Kreuzberger, Alexander Waniek, Carsten Jäger, Birgit Koch, Holger Cynis, Astrid Kehlen, Thomas Arendt, Maike Hartlage‐Rübsamen, Hans‐Ulrich Demuth, Steffen Roßner

    Gepubliceerd in 2014
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  19. 19
    Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease

    Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease door Jessica L. Wittnam, Erik Portelius, Henrik Zetterberg, Mikael K. Gustavsson, Stephan Schilling, Birgit C. P. Koch, Hans‐Ulrich Demuth, Kaj Blennow, Oliver Wirths, Thomas A. Bayer

    Gepubliceerd in 2012
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  20. 20
    Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms

    Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms door Maike Hartlage‐Rübsamen, Markus Morawski, Alexander Waniek, Carsten Jäger, Ulrike Zeitschel, Birgit C. P. Koch, Holger Cynis, Stephan Schilling, Reinhard Schliebs, Hans‐Ulrich Demuth, Steffen Roßner

    Gepubliceerd in 2011
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