检索结果 - Hans‐Ulrich Demuth

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  1. 1
    Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylproline <i>p</i>-nitroanilide in T-lymphocytes

    Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylproline <i>p</i>-nitroanilide in T-lymphocytes 由 E Schön, Hans‐Ulrich Demuth, A. Barth, S Ansorge

    出版 1984
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  2. 2
    Alternative pathways for production of β-amyloid peptides of Alzheimer's disease

    Alternative pathways for production of β-amyloid peptides of Alzheimer's disease 由 Vivian Hook, Israël Schechter, Hans‐Ulrich Demuth, Gregory Hook

    出版 2008
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  3. 3
    Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions

    Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions 由 Stephan Schilling, Torsten Hoffmann, Susanne Manhart, Matthias Hoffmann, Hans‐Ulrich Demuth

    出版 2004
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  4. 4
    Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Phenotype in 5XFAD Mice

    Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Ph... 由 Sadim Jawhar, Oliver Wirths, Stephan Schilling, Sigrid Graubner, Hans‐Ulrich Demuth, Thomas A. Bayer

    出版 2010
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  5. 5
    Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

    Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model 由 Oliver Wirths, Henning Breyhan, Holger Cynis, Stephan Schilling, Hans‐Ulrich Demuth, Thomas A. Bayer

    出版 2009
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  6. 6
    Modulation of inositol 1,4,5‐triphosphate concentration by prolyl endopeptidase inhibition

    Modulation of inositol 1,4,5‐triphosphate concentration by prolyl endopeptidase inhibition 由 Ingo Schulz, Bernd Gerhartz, Antje Neubauer, Andreas Holloschi, Ulrich Heiser, Mathias Hafner, Hans‐Ulrich Demuth

    出版 2002
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  7. 7
    Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study

    Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study 由 Jeffrey L. Frost, Bin Liu, Martin Kleinschmidt, Stephan Schilling, Hans‐Ulrich Demuth, Cynthia A. Lemere

    出版 2012
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  8. 8
    Long-Term Treatment With Dipeptidyl Peptidase IV Inhibitor Improves Hepatic and Peripheral Insulin Sensitivity in the VDF Zucker Rat

    Long-Term Treatment With Dipeptidyl Peptidase IV Inhibitor Improves Hepatic and Peripheral Insulin Sensitivity in the VDF Zucker Rat 由 J. Andrew Pospisilik, Sara Stafford, Hans‐Ulrich Demuth, Christopher H.S. McIntosh, Raymond A. Pederson

    出版 2002
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  9. 9
    Natural Products from Microalgae with Potential against Alzheimer’s Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors

    Natural Products from Microalgae with Potential against Alzheimer’s Disease: Sulfolipids Are Potent Glutaminyl Cyclase Inhibitors 由 Stephanie Hielscher-Michael, Carola Griehl, Mirko Buchholz, Hans‐Ulrich Demuth, Norbert Arnold, Ludger A. Wessjohann

    出版 2016
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  10. 10
    Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry

    Investigation of Glucose-dependent Insulinotropic Polypeptide(1-42) and Glucagon-like Peptide-1-(7-36) Degradation by Dipeptidyl Peptidase IV Using Matrix-assisted Laser Desorption... 由 Robert P. Pauly, Fred Rosche, Michael Wermann, Christopher H.S. McIntosh, Raymond A. Pederson, Hans‐Ulrich Demuth

    出版 1996
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  11. 11
    Dipeptidyl Peptidase IV-Resistant [<scp>d</scp>-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats

    Dipeptidyl Peptidase IV-Resistant [<scp>d</scp>-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats 由 Simon A. Hinke, Richard W. Gelling, Raymond A. Pederson, Susanne Manhart, Cuilan Nian, Hans‐Ulrich Demuth, Christopher H.S. McIntosh

    出版 2002
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  12. 12
    Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion

    Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion 由 Ingo Schulz, Ulrike Zeitschel, Thomas Rudolph, David Ruiz‐Carrillo, Jens‐Ulrich Rahfeld, Bernd Gerhartz, Volker Bigl, Hans‐Ulrich Demuth, Steffen Roßner

    出版 2005
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  13. 13
    The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

    The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism 由 Michael H. Engel, Torsten Hoffmann, Leona Wagner, Michael Wermann, Ulrich Heiser, R. Kiefersauer, Robert Huber, Wolfram Bode, Hans‐Ulrich Demuth, Hans Brandstetter

    出版 2003
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  14. 14
    Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

    Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor 由 C. Parthier, Martin Kleinschmidt, Piotr Neumann, Rainer Rudolph, Susanne Manhart, Dagmar Schlenzig, Jörg Fanghänel, Jens‐Ulrich Rahfeld, Hans‐Ulrich Demuth, Milton T. Stubbs

    出版 2007
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  15. 15
    Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase

    Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activat... 由 Jan A. Ehses, Vanbric R. Casilla, Tim Doty, J. Andrew Pospisilik, Kyle D. Winter, Hans‐Ulrich Demuth, Raymond A. Pederson, Christopher H.S. McIntosh

    出版 2003
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  16. 16
    Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon

    Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon 由 Simon A. Hinke, J. Andrew Pospisilik, Hans-Ulrich Demuth, Susanne Mannhart, Kerstin Kühn‐Wache, Torsten Hoffmann, Erica Nishimura, Raymond A. Pederson, Christopher H.S. McIntosh

    出版 2000
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  17. 17
    Regulation of Expression and Function of Dipeptidyl Peptidase 4 (DP4), DP8/9, and DP10 in Allergic Responses of the Lung in Rats

    Regulation of Expression and Function of Dipeptidyl Peptidase 4 (DP4), DP8/9, and DP10 in Allergic Responses of the Lung in Rats 由 J Schade, Michael Stephan, Andreas Schmiedl, Leona Wagner, André J. Niestroj, Hans‐Ulrich Demuth, Nadine Frerker, Christian Klemann, Kerstin Raber, Reinhard Pabst, Stephan von Hörsten

    出版 2007
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  18. 18
    Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease

    Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease 由 Markus Morawski, Stephan Schilling, Moritz Kreuzberger, Alexander Waniek, Carsten Jäger, Birgit Koch, Holger Cynis, Astrid Kehlen, Thomas Arendt, Maike Hartlage‐Rübsamen, Hans‐Ulrich Demuth, Steffen Roßner

    出版 2014
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  19. 19
    Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease

    Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease 由 Jessica L. Wittnam, Erik Portelius, Henrik Zetterberg, Mikael K. Gustavsson, Stephan Schilling, Birgit C. P. Koch, Hans‐Ulrich Demuth, Kaj Blennow, Oliver Wirths, Thomas A. Bayer

    出版 2012
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  20. 20
    Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms

    Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms 由 Maike Hartlage‐Rübsamen, Markus Morawski, Alexander Waniek, Carsten Jäger, Ulrike Zeitschel, Birgit C. P. Koch, Holger Cynis, Stephan Schilling, Reinhard Schliebs, Hans‐Ulrich Demuth, Steffen Roßner

    出版 2011
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