檢索結果 - Geoff Otto
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Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions 由 Christine M. Lovly, Abha A. Gupta, Doron Lipson, Geoff Otto, Tina Brennan, Catherine T. Chung, Scott C. Borinstein, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Cheryl M. Coffin
出版 2014Artigo -
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Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer 由 Nir Peled, Gary A. Palmer, Fred R. Hirsch, Murry W. Wynes, Maya Ilouze, Marileila Varella‐Garcia, Lior Soussan‐Gutman, Geoff Otto, Philip J. Stephens, Jeffrey S. Ross, Maureen Cronin, Doron Lipson, Vincent A. Miller
出版 2012Artigo -
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Genomic Profiling of Advanced-Stage, Metaplastic Breast Carcinoma by Next-Generation Sequencing Reveals Frequent, Targetable Genomic Abnormalities and Potential New Treatment Optio... 由 Jeffrey S. Ross, Sunil Badve, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Roman Yelensky, Doron Lipson, Siraj M. Ali, Deborah Morosini, Juliann Chliemlecki, Julia A. Elvin, Vincent A. Miller, Philip J. Stephens
出版 2015Artigo -
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BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition 由 Katherine E. Hutchinson, Doron Lipson, Philip J. Stephens, Geoff Otto, Brian D. Lehmann, Pamela L. Lyle, Cindy L. Vnencak‐Jones, Jeffrey S. Ross, Jennifer A. Pietenpol, Jeffrey A. Sosman, Igor Puzanov, Vincent A. Miller, William Pao
出版 2013Artigo -
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Relapsed Classic E-Cadherin (<i>CDH1</i>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of<i>HER2</i>(<i>ERBB2</i>) Gene Mutations 由 Jeffrey S. Ross, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Sean R. Downing, James Sun, Jie He, John A. Curran, Siraj M. Ali, Roman Yelensky, Doron Lipson, Gary A. Palmer, Vincent A. Miller, Philip J. Stephens
出版 2013Artigo -
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Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer 由 Jeffrey S. Ross, K Wang, Osama Elkadi, Ashley J. Tarasen, Llewelyn Foulke, Christine E. Sheehan, Geoff Otto, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, V.A. Miller, Philip J. Stephens
出版 2014Artigo -
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Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site 由 Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Geoff Otto, Emily White, Kiel Iwanik, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Rachel Erlich, Andrew Rankin, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, Vincent A. Miller, Philip J. Stephens
出版 2015Artigo -
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Blood-based biomarkers for cancer immunotherapy: Tumor mutational burden in blood (bTMB) is associated with improved atezolizumab (atezo) efficacy in 2L+ NSCLC (POPLAR and OAK) 由 David R. Gandara, Marcin Kowanetz, Tony Mok, Achim Rittmeyer, Louis Fehrenbacher, David Fabrizio, Geoff Otto, Christine M. Malboeuf, Daniel S. Lieber, Sarah Paul, Lukas C. Amler, Todd Riehl, Erica Schleifman, Craig Cummings, P. Hegde, Wei Zou, Anna Sandler, M. Ballinger, David S. Shames
出版 2017Artigo -
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Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy 由 Jeffrey S. Ross, Kai Wang, Rami N. Al‐Rohil, Tipu Nazeer, Christine E. Sheehan, Geoff Otto, Jie He, Gary A. Palmer, Roman Yelensky, Doron Lipson, Siraj M. Ali, Sohail Balasubramanian, John A. Curran, Lazlo Garcia, Kristen Mahoney, Sean R. Downing, Matthew Hawryluk, Vincent A. Miller, Philip J. Stephens
出版 2013Artigo -
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New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing 由 Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Rami N. Al‐Rohil, Janne V. Rand, David Jones, Hwa J. Lee, Christine E. Sheehan, Geoff Otto, Gary A. Palmer, Roman Yelensky, Doron Lipson, Deborah Morosini, Matthew Hawryluk, Daniel V.T. Catenacci, Vincent A. Miller, Chaitanya Churi, Siraj M. Ali, Philip J. Stephens
出版 2014Artigo -
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Kinase fusions are frequent in Spitz tumours and spitzoid melanomas 由 Thomas Wiesner, Jie He, Roman Yelensky, Rosaura Esteve‐Puig, Thomas Botton, Iwei Yeh, Doron Lipson, Geoff Otto, Kristina Brennan, Rajmohan Murali, M Garrido, Vincent A. Miller, Jeffrey S. Ross, Michael F. Berger, Alyssa J. Sparatta, Gabriele Palmedo, Lorenzo Cerroni, Klaus J. Busam, Heinz Kutzner, Maureen Cronin, Philip J. Stephens, Boris C. Bastian
出版 2014Artigo -
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<i>RICTOR</i> Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors 由 Haiying Cheng, Yiyu Zou, Jeffrey S. Ross, Kai Wang, Xuewen Liu, Balázs Halmos, Siraj M. Ali, Huijie Liu, Amit Verma, Cristina Montagna, Abraham Chachoua, Sanjay Goel, Edward L. Schwartz, Changcheng Zhu, Jidong Shan, Yiting Yu, Kira Gritsman, Roman Yelensky, Doron Lipson, Geoff Otto, Matthew Hawryluk, Philip J. Stephens, Vincent A. Miller, Bilal Piperdi, Román Pérez-Soler
出版 2015Artigo -
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Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms 由 Raajit K. Rampal, Jihae Ahn, Omar Abdel‐Wahab, Michelle Nahas, Kai Wang, Doron Lipson, Geoff Otto, Roman Yelensky, Todd Hricik, Anna Sophia McKenney, Gabriela Chiosis, Young Rock Chung, Suveg Pandey, Marcel R.M. van den Brink, Scott A. Armstrong, Ahmet Doǧan, Andrew M. Intlekofer, Taghi Manshouri, Christopher Y. Park, Srđan Verstovšek, Franck Rapaport, Philip J. Stephens, Vincent A. Miller, Ross L. Levine
出版 2014Artigo -
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A High Frequency of Activating Extracellular Domain <i>ERBB2</i> (<i>HER2</i>) Mutation in Micropapillary Urothelial Carcinoma 由 Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Rami N. Al‐Rohil, Tipu Nazeer, Christine E. Sheehan, Timothy A. Jennings, Geoff Otto, Amy Donahue, Jie He, Gary A. Palmer, Siraj M. Ali, Michelle Nahas, Geneva Young, Elaine LaBrecque, Garrett M. Frampton, Rachel Erlich, John A. Curran, Kristina Brennan, Sean R. Downing, Roman Yelensky, Doron Lipson, Matthew Hawryluk, Vincent A. Miller, Philip J. Stephens
出版 2013Artigo -
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Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias 由 K Wang, Marta Sánchez-Martín, X Wang, Kristina M. Knapp, Richard P. Koche, Ly Vu, Michelle Nahas, Jie He, Michael Hadler, Eytan M. Stein, Martin S. Tallman, Amy Donahue, Garrett M. Frampton, Doron Lipson, Sarah Roels, P. J. Stephens, Eric M. Sanford, Timothy A Brennan, Geoff Otto, Roman Yelensky, V. A. Miller, Michael G. Kharas, Ross L. Levine, Adolfo A. Ferrando, Scott A. Armstrong, Andrei V. Krivtsov
出版 2016Artigo -
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Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies 由 Doron Lipson, Marzia Capelletti, Roman Yelensky, Geoff Otto, Alex Parker, Mirna Jarosz, John A. Curran, Sohail Balasubramanian, Troy Bloom, Kristina Brennan, Amy Donahue, Sean R. Downing, Garrett M. Frampton, Lázaro Ibrahim Romero García, Frank Juhn, Kathy C Mitchell, Emily White, Jared White, Zac Zwirko, Tamar Peretz, Hovav Nechushtan, Lior Soussan‐Gutman, Young Tae Kim, Hidefumi Sasaki, Hyeong Ryul Kim, Seung-Il Park, Dalia Ercan, Christine E. Sheehan, Jeffrey S. Ross, Maureen Cronin, Pasi A. Jänne, Philip J. Stephens
出版 2012Artigo -
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Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor–Positive Breast Cancer 由 Rinath Jeselsohn, Roman Yelensky, Gilles Buchwalter, Garrett M. Frampton, Funda Meric‐Bernstam, Ana M. González-Angulo, Jaime Ferrer-Lozano, José Alejandro Pérez Fidalgo, Massimo Cristofanilli, Henry Gómez, Carlos L. Arteaga, Jennifer M. Giltnane, Justin M. Balko, Maureen Cronin, Mirna Jarosz, James Sun, Matthew Hawryluk, Doron Lipson, Geoff Otto, Jeffrey S. Ross, Addie Dvir, Lior Soussan‐Gutman, Ido Wolf, Tamar Rubinek, Lauren Gilmore, Stuart J. Schnitt, Steven E. Come, Lajos Pusztai, Philip Stephens, Myles Brown, Vincent A. Miller
出版 2014Artigo
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CDKN2A
Exon
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PI3K/AKT/mTOR pathway
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