Search Results - Geoff Otto

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  1. 1
    The Pathway of HCV IRES-Mediated Translation Initiation

    The Pathway of HCV IRES-Mediated Translation Initiation by Geoff Otto, Joseph D. Puglisi

    Published 2004
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  2. 2
    Ribosomal proteins mediate the hepatitis C virus IRES???HeLa 40S interaction

    Ribosomal proteins mediate the hepatitis C virus IRES???HeLa 40S interaction by Geoff Otto, Peter J. Lukavsky, Alissa M. Lancaster, Peter Sarnow, Joseph D. Puglisi

    Published 2002
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  3. 3
    Long, Processive Enzymatic DNA Synthesis Using 100% Dye-Labeled Terminal Phosphate-Linked Nucleotides

    Long, Processive Enzymatic DNA Synthesis Using 100% Dye-Labeled Terminal Phosphate-Linked Nucleotides by Jonas Korlach, Arek Bibillo, Jeffrey Wegener, Paul Peluso, Thang Pham, Insil Park, Sonya Clark, Geoff Otto, Stephen W. Turner

    Published 2008
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  4. 4
    Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions

    Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions by Christine M. Lovly, Abha A. Gupta, Doron Lipson, Geoff Otto, Tina Brennan, Catherine T. Chung, Scott C. Borinstein, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Cheryl M. Coffin

    Published 2014
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  5. 5
    Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer

    Next-Generation Sequencing Identifies and Immunohistochemistry Confirms a Novel Crizotinib-Sensitive ALK Rearrangement in a Patient with Metastatic Non–Small-Cell Lung Cancer by Nir Peled, Gary A. Palmer, Fred R. Hirsch, Murry W. Wynes, Maya Ilouze, Marileila Varella‐Garcia, Lior Soussan‐Gutman, Geoff Otto, Philip J. Stephens, Jeffrey S. Ross, Maureen Cronin, Doron Lipson, Vincent A. Miller

    Published 2012
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  6. 6
    Genomic Profiling of Advanced-Stage, Metaplastic Breast Carcinoma by Next-Generation Sequencing Reveals Frequent, Targetable Genomic Abnormalities and Potential New Treatment Options

    Genomic Profiling of Advanced-Stage, Metaplastic Breast Carcinoma by Next-Generation Sequencing Reveals Frequent, Targetable Genomic Abnormalities and Potential New Treatment Optio... by Jeffrey S. Ross, Sunil Badve, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Roman Yelensky, Doron Lipson, Siraj M. Ali, Deborah Morosini, Juliann Chliemlecki, Julia A. Elvin, Vincent A. Miller, Philip J. Stephens

    Published 2015
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  7. 7
    BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition

    BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition by Katherine E. Hutchinson, Doron Lipson, Philip J. Stephens, Geoff Otto, Brian D. Lehmann, Pamela L. Lyle, Cindy L. Vnencak‐Jones, Jeffrey S. Ross, Jennifer A. Pietenpol, Jeffrey A. Sosman, Igor Puzanov, Vincent A. Miller, William Pao

    Published 2013
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  8. 8
    Relapsed Classic E-Cadherin (<i>CDH1</i>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of<i>HER2</i>(<i>ERBB2</i>) Gene Mutations

    Relapsed Classic E-Cadherin (<i>CDH1</i>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of<i>HER2</i>(<i>ERBB2</i>) Gene Mutations by Jeffrey S. Ross, Kai Wang, Christine E. Sheehan, Ann Boguniewicz, Geoff Otto, Sean R. Downing, James Sun, Jie He, John A. Curran, Siraj M. Ali, Roman Yelensky, Doron Lipson, Gary A. Palmer, Vincent A. Miller, Philip J. Stephens

    Published 2013
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  9. 9
    Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer

    Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer by Jeffrey S. Ross, K Wang, Osama Elkadi, Ashley J. Tarasen, Llewelyn Foulke, Christine E. Sheehan, Geoff Otto, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, V.A. Miller, Philip J. Stephens

    Published 2014
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  10. 10
    Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site

    Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site by Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Geoff Otto, Emily White, Kiel Iwanik, Gary A. Palmer, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Rachel Erlich, Andrew Rankin, Siraj M. Ali, Julia A. Elvin, Deborah Morosini, Vincent A. Miller, Philip J. Stephens

    Published 2015
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  11. 11
    Blood-based biomarkers for cancer immunotherapy: Tumor mutational burden in blood (bTMB) is associated with improved atezolizumab (atezo) efficacy in 2L+ NSCLC (POPLAR and OAK)

    Blood-based biomarkers for cancer immunotherapy: Tumor mutational burden in blood (bTMB) is associated with improved atezolizumab (atezo) efficacy in 2L+ NSCLC (POPLAR and OAK) by David R. Gandara, Marcin Kowanetz, Tony Mok, Achim Rittmeyer, Louis Fehrenbacher, David Fabrizio, Geoff Otto, Christine M. Malboeuf, Daniel S. Lieber, Sarah Paul, Lukas C. Amler, Todd Riehl, Erica Schleifman, Craig Cummings, P. Hegde, Wei Zou, Anna Sandler, M. Ballinger, David S. Shames

    Published 2017
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  12. 12
    Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy

    Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy by Jeffrey S. Ross, Kai Wang, Rami N. Al‐Rohil, Tipu Nazeer, Christine E. Sheehan, Geoff Otto, Jie He, Gary A. Palmer, Roman Yelensky, Doron Lipson, Siraj M. Ali, Sohail Balasubramanian, John A. Curran, Lazlo Garcia, Kristen Mahoney, Sean R. Downing, Matthew Hawryluk, Vincent A. Miller, Philip J. Stephens

    Published 2013
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  13. 13
    New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing

    New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing by Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Rami N. Al‐Rohil, Janne V. Rand, David Jones, Hwa J. Lee, Christine E. Sheehan, Geoff Otto, Gary A. Palmer, Roman Yelensky, Doron Lipson, Deborah Morosini, Matthew Hawryluk, Daniel V.T. Catenacci, Vincent A. Miller, Chaitanya Churi, Siraj M. Ali, Philip J. Stephens

    Published 2014
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  14. 14
    Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

    Kinase fusions are frequent in Spitz tumours and spitzoid melanomas by Thomas Wiesner, Jie He, Roman Yelensky, Rosaura Esteve‐Puig, Thomas Botton, Iwei Yeh, Doron Lipson, Geoff Otto, Kristina Brennan, Rajmohan Murali, M Garrido, Vincent A. Miller, Jeffrey S. Ross, Michael F. Berger, Alyssa J. Sparatta, Gabriele Palmedo, Lorenzo Cerroni, Klaus J. Busam, Heinz Kutzner, Maureen Cronin, Philip J. Stephens, Boris C. Bastian

    Published 2014
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  15. 15
    <i>RICTOR</i> Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors

    <i>RICTOR</i> Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors by Haiying Cheng, Yiyu Zou, Jeffrey S. Ross, Kai Wang, Xuewen Liu, Balázs Halmos, Siraj M. Ali, Huijie Liu, Amit Verma, Cristina Montagna, Abraham Chachoua, Sanjay Goel, Edward L. Schwartz, Changcheng Zhu, Jidong Shan, Yiting Yu, Kira Gritsman, Roman Yelensky, Doron Lipson, Geoff Otto, Matthew Hawryluk, Philip J. Stephens, Vincent A. Miller, Bilal Piperdi, Román Pérez-Soler

    Published 2015
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  16. 16
    Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms

    Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms by Raajit K. Rampal, Jihae Ahn, Omar Abdel‐Wahab, Michelle Nahas, Kai Wang, Doron Lipson, Geoff Otto, Roman Yelensky, Todd Hricik, Anna Sophia McKenney, Gabriela Chiosis, Young Rock Chung, Suveg Pandey, Marcel R.M. van den Brink, Scott A. Armstrong, Ahmet Doǧan, Andrew M. Intlekofer, Taghi Manshouri, Christopher Y. Park, Srđan Verstovšek, Franck Rapaport, Philip J. Stephens, Vincent A. Miller, Ross L. Levine

    Published 2014
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  17. 17
    A High Frequency of Activating Extracellular Domain <i>ERBB2</i> (<i>HER2</i>) Mutation in Micropapillary Urothelial Carcinoma

    A High Frequency of Activating Extracellular Domain <i>ERBB2</i> (<i>HER2</i>) Mutation in Micropapillary Urothelial Carcinoma by Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Rami N. Al‐Rohil, Tipu Nazeer, Christine E. Sheehan, Timothy A. Jennings, Geoff Otto, Amy Donahue, Jie He, Gary A. Palmer, Siraj M. Ali, Michelle Nahas, Geneva Young, Elaine LaBrecque, Garrett M. Frampton, Rachel Erlich, John A. Curran, Kristina Brennan, Sean R. Downing, Roman Yelensky, Doron Lipson, Matthew Hawryluk, Vincent A. Miller, Philip J. Stephens

    Published 2013
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  18. 18
    Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias

    Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias by K Wang, Marta Sánchez-Martín, X Wang, Kristina M. Knapp, Richard P. Koche, Ly Vu, Michelle Nahas, Jie He, Michael Hadler, Eytan M. Stein, Martin S. Tallman, Amy Donahue, Garrett M. Frampton, Doron Lipson, Sarah Roels, P. J. Stephens, Eric M. Sanford, Timothy A Brennan, Geoff Otto, Roman Yelensky, V. A. Miller, Michael G. Kharas, Ross L. Levine, Adolfo A. Ferrando, Scott A. Armstrong, Andrei V. Krivtsov

    Published 2016
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  19. 19
    Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

    Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies by Doron Lipson, Marzia Capelletti, Roman Yelensky, Geoff Otto, Alex Parker, Mirna Jarosz, John A. Curran, Sohail Balasubramanian, Troy Bloom, Kristina Brennan, Amy Donahue, Sean R. Downing, Garrett M. Frampton, Lázaro Ibrahim Romero García, Frank Juhn, Kathy C Mitchell, Emily White, Jared White, Zac Zwirko, Tamar Peretz, Hovav Nechushtan, Lior Soussan‐Gutman, Young Tae Kim, Hidefumi Sasaki, Hyeong Ryul Kim, Seung-Il Park, Dalia Ercan, Christine E. Sheehan, Jeffrey S. Ross, Maureen Cronin, Pasi A. Jänne, Philip J. Stephens

    Published 2012
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  20. 20
    Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor–Positive Breast Cancer

    Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor–Positive Breast Cancer by Rinath Jeselsohn, Roman Yelensky, Gilles Buchwalter, Garrett M. Frampton, Funda Meric‐Bernstam, Ana M. González-Angulo, Jaime Ferrer-Lozano, José Alejandro Pérez Fidalgo, Massimo Cristofanilli, Henry Gómez, Carlos L. Arteaga, Jennifer M. Giltnane, Justin M. Balko, Maureen Cronin, Mirna Jarosz, James Sun, Matthew Hawryluk, Doron Lipson, Geoff Otto, Jeffrey S. Ross, Addie Dvir, Lior Soussan‐Gutman, Ido Wolf, Tamar Rubinek, Lauren Gilmore, Stuart J. Schnitt, Steven E. Come, Lajos Pusztai, Philip Stephens, Myles Brown, Vincent A. Miller

    Published 2014
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