Search Results - Gareth R. Howell

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  1. 1
    The Complex Role of Neuroinflammation in Glaucoma

    The Complex Role of Neuroinflammation in Glaucoma by Ileana Soto, Gareth R. Howell

    Published 2014
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  2. 2
    Intrinsic axonal degeneration pathways are critical for glaucomatous damage

    Intrinsic axonal degeneration pathways are critical for glaucomatous damage by Gareth R. Howell, Ileana Soto, Richard T. Libby, Simon W. M. John

    Published 2012
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  3. 3
    Toward more predictive genetic mouse models of Alzheimer's disease

    Toward more predictive genetic mouse models of Alzheimer's disease by Kristen D. Onos, Stacey J. Sukoff Rizzo, Gareth R. Howell, Michael Sasner

    Published 2015
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  4. 4
    Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease

    Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease by Harriet M. Jackson, Ileana Soto, Leah Graham, Gregory W. Carter, Gareth R. Howell

    Published 2013
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  5. 5
    Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma

    Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma by Ryan H. Berry, Juan Qu, Simon W. M. John, Gareth R. Howell, Tatjana Jakobs

    Published 2015
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  6. 6
    Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity

    Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity by Hongtian Yang, Leah Graham, Alaina M. Reagan, Weronika Grabowska, William Schott, Gareth R. Howell

    Published 2019
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  7. 7
    Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data

    Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data by Gareth R. Howell, David O. Walton, Benjamin L. King, Richard T. Libby, Simon W. M. John

    Published 2011
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  8. 8
    Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

    Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice by Gareth R. Howell, Ileana Soto, Margaret M. Ryan, Leah Graham, Richard S. Smith, Simon W. M. John

    Published 2013
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  9. 9
    Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

    Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease by Leah Graham, Jeffrey M. Harder, Ileana Soto, Wilhelmine N. de Vries, Simon W. M. John, Gareth R. Howell

    Published 2016
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  10. 10
    Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer’s disease

    Natural genetic variation determines microglia heterogeneity in wild-derived mouse models of Alzheimer’s disease by Hongtian Yang, Kristen D. Onos, Kwangbom Choi, Kelly J. Keezer, Daniel A. Skelly, Gregory W. Carter, Gareth R. Howell

    Published 2021
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  11. 11
    The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice

    The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice by Kate E. Foley, Amanda A. Hewes, Dylan Garceau, Kevin P. Kotredes, Gregory W. Carter, Michael Sasner, Gareth R. Howell

    Published 2022
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  12. 12
    Microglia depletion leads to increased susceptibility to ocular hypertension-dependent glaucoma

    Microglia depletion leads to increased susceptibility to ocular hypertension-dependent glaucoma by Cory A. Diemler, Michael MacLean, Sarah E. Heuer, Amanda A. Hewes, Olivia J. Marola, Richard T. Libby, Gareth R. Howell

    Published 2024
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  13. 13
    Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma

    Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma by Gareth R. Howell, Katharine H. MacNicoll, Catherine Braine, Ileana Soto, Danilo G. Macalinao, Gregory L. Sousa, Simon W. M. John

    Published 2014
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  14. 14
    Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma

    Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma by Pete A. Williams, Gareth R. Howell, Jessica M. Barbay, Catherine Braine, Gregory L. Sousa, Simon W. M. John, James P. Morgan

    Published 2013
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  15. 15
    Exercise prevents obesity-induced cognitive decline and white matter damage in mice

    Exercise prevents obesity-induced cognitive decline and white matter damage in mice by Leah Graham, Weronika Grabowska, Yoona Chun, Shannon L. Risacher, Vivek M. Philip, Andrew J. Saykin, Stacey J. Sukoff Rizzo, Gareth R. Howell

    Published 2019
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  16. 16
    Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1

    Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1 by Gareth R. Howell, Richard T. Libby, Jeffrey K. Marchant, Lawriston A. Wilson, Ioan M Cosma, Richard S. Smith, Michael G. Anderson, Simon W. M. John

    Published 2007
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  17. 17
    Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice

    Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice by Jeffrey M. Harder, Pete A. Williams, Catherine Braine, Hongtian Yang, Jocelyn M. Thomas, Nicole E. Foxworth, Simon W. M. John, Gareth R. Howell

    Published 2020
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  18. 18
    APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction

    APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction by Ileana Soto, Leah Graham, Hannah J. Richter, Stephen N. Simeone, Jake E. Radell, Weronika Grabowska, William K. Funkhouser, Megan C. Howell, Gareth R. Howell

    Published 2015
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  19. 19
    Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

    Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma by Pete A. Williams, James R. Tribble, Keating W. Pepper, Stephen D. Cross, B. Paul Morgan, James P. Morgan, Simon W. M. John, Gareth R. Howell

    Published 2016
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  20. 20
    Genetic context modulates aging and degeneration in the murine retina

    Genetic context modulates aging and degeneration in the murine retina by Olivia J. Marola, Michael MacLean, Travis Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell

    Published 2025
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