Rezultati - Gabriele Lignani

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  1. 1
    Gene therapy and editing: Novel potential treatments for neuronal channelopathies

    Gene therapy and editing: Novel potential treatments for neuronal channelopathies od Robert C. Wykes, Gabriele Lignani

    Izdano 2017
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  2. 2
    Homeostatic Plasticity in Epilepsy

    Homeostatic Plasticity in Epilepsy od Gabriele Lignani, Pietro Baldelli, Vincenzo Marra

    Izdano 2020
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  3. 3
    Recent advances in gene therapy for neurodevelopmental disorders with epilepsy

    Recent advances in gene therapy for neurodevelopmental disorders with epilepsy od Thomas J. Turner, Clara Zourray, Stéphanie Schorge, Gabriele Lignani

    Izdano 2020
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  4. 4
    Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels

    Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels od Lucian Medrihan, Fabrizia Cesca, Andrea Raimondi, Gabriele Lignani, Pietro Baldelli, Fabio Benfenati

    Izdano 2013
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  5. 5
    Strategies to maximize the performance of a STED microscope

    Strategies to maximize the performance of a STED microscope od Silvia Galiani, Benjamin Harke, Giuseppe Vicidomini, Gabriele Lignani, Fabio Benfenati, Alberto Diaspro, Paolo Bianchini

    Izdano 2012
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  6. 6
    Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity

    Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity od Gabriele Lignani, Andrea Raimondi, Enrico Ferrea, Anna Rocchi, Francesco Paonessa, Fabrizia Cesca, Marta Orlando, Tatiana Tkatch, Flavia Valtorta, Patrick Cossette, Pietro Baldelli, Fabio Benfenati

    Izdano 2013
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  7. 7
    Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors

    Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors od Massimiliano Caiazzo, Serena Giannelli, Pierluigi Valente, Gabriele Lignani, Annamaria Carissimo, Alessandro Sessa, Gaia Colasante, Rosa Bartolomeo, Luca Massimino, Stefano Ferroni, Carmine Settembre, Fabio Benfenati, Vania Broccoli

    Izdano 2014
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  8. 8
    Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses

    Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses od Anne M.J. Verstegen, Erica Tagliatti, Gabriele Lignani, Antonella Marte, Tamar Stolero, Merav Atias, Anna Corradi, Flavia Valtorta, Daniel Gitler, Franco Onofri, Anna Fassio, Fabio Benfenati

    Izdano 2014
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  9. 9
    REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability

    REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability od Davide Pozzi, Gabriele Lignani, Enrico Ferrea, Andrea Contestabile, Francesco Paonessa, Rosalba D’Alessandro, Pellegrino Lippiello, Davide Boido, Anna Fassio, Jacopo Meldolesi, Flavia Valtorta, Fabio Benfenati, Pietro Baldelli

    Izdano 2013
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  10. 10
    Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome

    Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome od Nicholas Valassina, Simone Brusco, Alessia Salamone, Linda Serra, Mirko Luoni, Serena Giannelli, Simone Bido, Luca Massimino, Federica Ungaro, Pietro Giuseppe Mazzara, Patrizia D’Adamo, Gabriele Lignani, Vania Broccoli, Gaia Colasante

    Izdano 2022
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  11. 11
    Anti-seizure gene therapy for focal cortical dysplasia

    Anti-seizure gene therapy for focal cortical dysplasia od Amanda Almacellas Barbanoj, R. Graham, Benito Maffei, Jenna C. Carpenter, Marco Leite, Justin Hoke, Felisia Hardjo, James Scott-Solache, Christos Chimonides, Stéphanie Schorge, Dimitri M. Kullmann, Vincent Magloire, Gabriele Lignani

    Izdano 2023
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  12. 12
    In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy

    In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy od Gaia Colasante, Yichen Qiu, Luca Massimino, Claudia Di Berardino, Jonathan Cornford, Albert Snowball, Mikail Weston, Steffan P. Jones, Serena Giannelli, Andreas Lieb, Stéphanie Schorge, Dimitri M. Kullmann, Vania Broccoli, Gabriele Lignani

    Izdano 2020
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  13. 13
    Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics

    Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics od Mikail Weston, Teresa Kaserer, Angela Wu, Alexandre Mouravlev, Jenna C. Carpenter, Albert Snowball, Samuel Knauß, Melanie von Schimmelmann, Matthew J. During, Gabriele Lignani, Stéphanie Schorge, Deborah Young, Dimitri M. Kullmann, Andreas Lieb

    Izdano 2019
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  14. 14
    TAAR1 Modulates Cortical Glutamate NMDA Receptor Function

    TAAR1 Modulates Cortical Glutamate NMDA Receptor Function od Stefano Espinoza, Gabriele Lignani, Lucia Caffino, Silvia Maggi, Ilya Sukhanov, Damiana Leo, Liudmila Mus, Marco Emanuele, Giuseppe Ronzitti, Anja Harmeier, Lucian Medrihan, Tatyana D. Sotnikova, Evelina Chieregatti, Marius C. Hoener, Fabio Benfenati, Valter Tucci, Fabio Fumagalli, Raul R. Gainetdinov

    Izdano 2015
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  15. 15
    Neurodevelopmental and synaptic defects in <i>DNAJC6</i> parkinsonism, amenable to gene therapy

    Neurodevelopmental and synaptic defects in <i>DNAJC6</i> parkinsonism, amenable to gene therapy od Lucia Abela, Lorita Gianfrancesco, Erica Tagliatti, Giada Rossignoli, Katy Barwick, Clara Zourray, Kimberley M. Reid, Dimitri Budinger, Joanne Ng, John R. Counsell, Arlo Simpson, Toni S. Pearson, Simon Edvardson, Orly Elpeleg, Frances M. Brodsky, Gabriele Lignani, Serena Barral, Manju A. Kurian

    Izdano 2024
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  16. 16
    dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

    dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice od Gaia Colasante, Gabriele Lignani, Simone Brusco, Claudia Di Berardino, Jenna C. Carpenter, Serena Giannelli, Nicholas Valassina, Simone Bido, Raffaele Ricci, Valerio Castoldi, Silvia Marenna, Timothy W. Church, Luca Massimino, Giuseppe Morabito, Fabio Benfenati, Stéphanie Schorge, Letizia Leocani, Dimitri M. Kullmann, Vania Broccoli

    Izdano 2019
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  17. 17
    Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming

    Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming od Gaia Colasante, Gabriele Lignani, Alicia Rubio, Lucian Medrihan, Latefa Yekhlef, Alessandro Sessa, Luca Massimino, Serena Giannelli, Silvio Sacchetti, Massimiliano Caiazzo, Damiana Leo, Dimitra Alexopoulou, Maria Teresa Dell’Anno, Ernesto Ciabatti, Marta Orlando, Michèle Studer, Andreas Dahl, Raul R. Gainetdinov, Stefano Taverna, Fabio Benfenati, Vania Broccoli

    Izdano 2015
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  18. 18
    On-demand cell-autonomous gene therapy for brain circuit disorders

    On-demand cell-autonomous gene therapy for brain circuit disorders od Yichen Qiu, Nathanael O’Neill, Benito Maffei, Clara Zourray, Amanda Almacellas‐Barbanoj, Jenna C. Carpenter, Steffan P. Jones, Marco Leite, Thomas J. Turner, Francisco C. Moreira, Albert Snowball, Tawfeeq Shekh‐Ahmad, Vincent Magloire, Serena Barral, Manju A. Kurian, Matthew C. Walker, Stéphanie Schorge, Dimitri M. Kullmann, Gabriele Lignani

    Izdano 2022
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  19. 19
    Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism

    Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism od Joanne Ng, Serena Barral, Carmen De La Fuente Barrigon, Gabriele Lignani, Fatma A. Erdem, Rebecca L. Wallings, Riccardo Privolizzi, Giada Rossignoli, Haya Alrashidi, Sonja Heasman, Esther Meyer, Adeline Ngoh, Simon Pope, Rajvinder Karda, Dany Perocheau, Julien Baruteau, Natalie Suff, Juan Antinao Díaz, Stéphanie Schorge, Jane Vowles, Lucy Marshall, Sally A. Cowley, Sonja Sučić, Michael Freissmuth, John R. Counsell, Richard Wade‐Martins, Simon Heales, Ahad A. Rahim, Maximilien Bencze, Simon N. Waddington, Manju A. Kurian

    Izdano 2021
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  20. 20
    Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

    Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo od Liam Kempthorne, Deniz Vaizoglu, Alexander J. Cammack, Mireia Carcolé, Maxine P. Roberts, Alla Mikheenko, Alessia Fisher, Pacharaporn Suklai, Bhavana Muralidharan, François Kroll, Thomas G. Moens, Lidia Yshii, Stijn Verschoren, Benedikt V. Hölbling, Francisco C. Moreira, Eszter Katona, Rachel Coneys, Paula de Oliveira, Yong-Jie Zhang, Karen Jansen, Lillian M. Daughrity, Alexander McGown, Tennore Ramesh, Ludo Van Den Bosch, Gabriele Lignani, Rahimin Affandi Abdul Rahim, Alyssa N. Coyne, Leonard Petrucelli, Jason Rihel, Adrian M. Isaacs

    Izdano 2025
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