Search Results - Esra A. Akbay

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  1. 1
    Multiple Interaction Domains in FtsL, a Protein Component of the Widely Conserved Bacterial FtsLBQ Cell Division Complex

    Multiple Interaction Domains in FtsL, a Protein Component of the Widely Conserved Bacterial FtsLBQ Cell Division Complex by Mark D. Gonzalez, Esra A. Akbay, Dana Boyd, Jon Beckwith

    Published 2010
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  2. 2
    Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase

    Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase by Salim Abdisalaam, Souparno Bhattacharya, Shibani Mukherjee, Debapriya Sinha, Srinivasan Kalayarasan, Mingrui Zhu, Esra A. Akbay, Hesham A. Sadek, Jerry W. Shay, Aroumougame Asaithamby

    Published 2020
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  3. 3
    Genomewide Discovery and Classification of Candidate Ovarian Fertility Genes in the Mouse

    Genomewide Discovery and Classification of Candidate Ovarian Fertility Genes in the Mouse by Teresa D. Gallardo, George B. John, Lane Shirley, Cristina M. Contreras, Esra A. Akbay, J. Marshall Haynie, S. Ward, Meredith J. Shidler, Diego H. Castrillón

    Published 2007
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  4. 4
    Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load

    Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load by Hao‐Dong Li, Ileana Cuevas, Musi Zhang, Changzheng Lu, Md Maksudul Alam, Yang‐Xin Fu, Ming You, Esra A. Akbay, He Zhang, Diego H. Castrillón

    Published 2018
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  5. 5
    <i>Lkb1</i>inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy

    <i>Lkb1</i>inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy by Cristina M. Contreras, Esra A. Akbay, Teresa D. Gallardo, J. Marshall Haynie, Sreenath V. Sharma, Osamu Tagao, Nabeel Bardeesy, Masaya Takahashi, Jeff Settleman, Kwok‐Kin Wong, Diego H. Castrillón

    Published 2010
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  6. 6
    Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas

    Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas by Cristina M. Contreras, Sushma Gurumurthy, J. Marshall Haynie, Lane Shirley, Esra A. Akbay, Shana N. Wingo, John O. Schorge, Russell R. Broaddus, Kwok‐Kin Wong, Nabeel Bardeesy, Diego H. Castrillón

    Published 2008
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  7. 7
    Identification and characterization of an alternative cancer-derived PD-L1 splice variant

    Identification and characterization of an alternative cancer-derived PD-L1 splice variant by Nadia B. Hassounah, Venkat S. Malladi, Yi Huang, Samuel S. Freeman, Ellen M. Beauchamp, Shohei Koyama, Nicholas Souders, Sunil Martin, Glenn Dranoff, Kwok‐Kin Wong, Chandra Sekhar Pedamallu, Peter S. Hammerman, Esra A. Akbay

    Published 2018
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  8. 8
    Novel and potent MICA/B antibody is therapeutically effective in<i>KRAS LKB1</i>mutant lung cancer models

    Novel and potent MICA/B antibody is therapeutically effective in<i>KRAS LKB1</i>mutant lung cancer models by Ryan Kowash, Manoj K. Sabnani, Laura Gray, Qing Deng, N. Saleh, Luc Girard, Yujiro Naito, Kitamura Masahiro, John D. Minna, David E. Gerber, Shohei Koyama, Zhiqian Lucy Liu, Hemanta Baruah, Esra A. Akbay

    Published 2025
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  9. 9
    Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models

    Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models by Grit S. Herter-Sprie, Houari Korideck, Camilla L. Christensen, Jan M. Herter, Kevin Rhee, Ross Berbeco, D. Bennett, Esra A. Akbay, David Kozono, Raymond H. Mak, G. Mike Makrigiorgos, Alec C. Kimmelman, Kwok‐Kin Wong

    Published 2014
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  10. 10
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer by Hyejin Choi, Jiehui Deng, Shuai Li, Tarik Silk, Lauren Dong, Elliott J. Brea, Sean Houghton, David Redmond, Hong Zhong, Jonathan Boiarsky, Esra A. Akbay, Paul D. Smith, Taha Merghoub, Kwok‐Kin Wong, Jedd D. Wolchok

    Published 2019
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  11. 11
    Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis

    Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis by Mingrui Zhu, Yi Huang, Matthew E. Bender, Luc Girard, Rahul K. Kollipara, Buse Eglenen-Polat, Yujiro Naito, Trisha K. Savage, Kenneth E. Huffman, Shohei Koyama, Atsushi Kumanogoh, John D. Minna, Jane E. Johnson, Esra A. Akbay

    Published 2021
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  12. 12
    Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution

    Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution by Hongyi Zhang, Xuexin Yu, Jianfeng Ye, Huiyu Li, Jing Hu, Yuhao Tan, Yan Fang, Esra A. Akbay, Fulong Yu, Chen Weng, Vijay G. Sankaran, Robert Bachoo, Elizabeth A. Maher, John D. Minna, Anli Zhang, Bo Li

    Published 2023
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  13. 13
    Somatic LKB1 Mutations Promote Cervical Cancer Progression

    Somatic LKB1 Mutations Promote Cervical Cancer Progression by Shana N. Wingo, Teresa D. Gallardo, Esra A. Akbay, Mei‐Chih Liang, Cristina M. Contreras, Todd Boren, Takeshi Shimamura, David S. Miller, Norman E. Sharpless, Nabeel Bardeesy, David J. Kwiatkowski, John O. Schorge, Kwok‐Kin Wong, Diego H. Castrillón

    Published 2009
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  14. 14
    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer

    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer by Takeshi Shimamura, Zhao Chen, Margaret Soucheray, Julián Carretero, Eiki Kikuchi, Jeremy H. Tchaicha, Yandi Gao, Katherine A. Cheng, Travis J. Cohoon, Jun Qi, Esra A. Akbay, Alec C. Kimmelman, Andrew L. Kung, James E. Bradner, Kwok‐Kin Wong

    Published 2013
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  15. 15
    Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity

    Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity by Juan J. Miret, Paul T. Kirschmeier, Shohei Koyama, Mingrui Zhu, Yvonne Y. Li, Yujiro Naito, Min Wu, Venkat S. Malladi, Wei Huang, William H. Walker, Sangeetha Palakurthi, Glenn Dranoff, Peter S. Hammerman, Chad V. Pecot, Kwok‐Kin Wong, Esra A. Akbay

    Published 2019
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  16. 16
    A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer

    A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer by Buse Eglenen-Polat, Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni, Mingrui Zhu, Kenian Chen, Matthew E. Bender, Ilgen Mender, Victor Stastny, Benjamin J. Drapkin, Prithvi Raj, John D. Minna, Lin Xu, Jerry W. Shay, Esra A. Akbay

    Published 2024
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  17. 17
    Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden

    Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden by Mingrui Zhu, Jiwoong Kim, Qing Deng, Biagio Ricciuti, Joao V. Alessi, Buse Eglenen-Polat, Matthew E. Bender, Hai-Cheng Huang, Ryan R. Kowash, Ileana Cuevas, Zachary T. Bennett, Jinming Gao, John D. Minna, Diego H. Castrillón, Mark M. Awad, Lin Xu, Esra A. Akbay

    Published 2023
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  18. 18
    Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in <i>ALK</i>-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance

    Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in <i>ALK</i>-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance by Zhao Chen, Esra A. Akbay, Oliver R. Mikse, Tanya Tupper, Katherine A. Cheng, Yuchuan Wang, Xiaohong Tan, Abigail Altabef, Sue-Ann Woo, Liang Chen, Jacob B. Reibel, Pasi A. Jänne, Norman E. Sharpless, Jeffrey A. Engelman, Geoffrey I. Shapiro, Andrew L. Kung, Kwok‐Kin Wong

    Published 2013
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  19. 19
    EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer

    EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer by Ke Gong, Gao Guo, Nishah Panchani, Matthew E. Bender, David E. Gerber, John D. Minna, Farjana Fattah, Boning Gao, Michael Peyton, Kemp H. Kernstine, Bipasha Mukherjee, Sandeep Burma, Cheng-Ming Chiang, Shanrong Zhang, Adwait Amod Sathe, Chao Xing, Kathryn H. Dao, Dawen Zhao, Esra A. Akbay, Amyn A. Habib

    Published 2020
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  20. 20
    Development of Selective Covalent Janus Kinase 3 Inhibitors

    Development of Selective Covalent Janus Kinase 3 Inhibitors by Li Tan, Koshi Akahane, Randall McNally, Kathleen M. S. E. Reyskens, Scott B. Ficarro, Suhu Liu, Grit S. Herter-Sprie, Shohei Koyama, Michael J. Pattison, Katherine Labella, Liv Johannessen, Esra A. Akbay, Kwok‐Kin Wong, David A. Frank, Jarrod A. Marto, Thomas Look, J. Simon C. Arthur, Michael J. Eck, Nathanael S. Gray

    Published 2015
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