Zoekresultaten - Dimitrios L. Wagner

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  1. 1
    Cas9-directed immune tolerance in humans—a model to evaluate regulatory T cells in gene therapy?

    Cas9-directed immune tolerance in humans—a model to evaluate regulatory T cells in gene therapy? door Dimitrios L. Wagner, Lena Peter, Michael Schmueck‐Henneresse

    Gepubliceerd in 2021
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  2. 2
    Review: Sustainable Clinical Development of CAR-T Cells – Switching From Viral Transduction Towards CRISPR-Cas Gene Editing

    Review: Sustainable Clinical Development of CAR-T Cells – Switching From Viral Transduction Towards CRISPR-Cas Gene Editing door Dimitrios L. Wagner, Ulrike Koehl, Markus Chmielewski, Christoph Scheid, Renata Stripecke

    Gepubliceerd in 2022
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  3. 3
    Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours

    Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours door Christian Flugel, Robbie G. Majzner, Giedre Krenciute, Gianpietro Dotti, Stanley R. Riddell, Dimitrios L. Wagner, Mohamed Abou‐El‐Enein

    Gepubliceerd in 2022
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  4. 4
    High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population

    High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population door Dimitrios L. Wagner, Leila Amini, Désirée J. Wendering, Lisa-Marie Burkhardt, Levent Akyüz, Petra Reinke, Hans‐Dieter Volk, Michael Schmueck‐Henneresse

    Gepubliceerd in 2018
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  5. 5
    Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications

    Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications door Leila Amini, Jenny Greig, Michael Schmueck‐Henneresse, Hans‐Dieter Volk, Séverine Bézie, Petra Reinke, Carole Guillonneau, Dimitrios L. Wagner, Ignacio Anegón

    Gepubliceerd in 2021
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  6. 6
    Daratumumab for the treatment of refractory ANCA-associated vasculitis

    Daratumumab for the treatment of refractory ANCA-associated vasculitis door Lennard Ostendorf, Marie E. Burns, Dimitrios L. Wagner, Philipp Enghard, Kerstin Amann, Henrik E. Mei, Kai‐Uwe Eckardt, Evelyn Seelow, Adrian Schreiber

    Gepubliceerd in 2023
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  7. 7
    CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies

    CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies door Diogo Gomes‐Silva, Madhuwanti Srinivasan, Sandhya Sharma, Ciaran M. Lee, Dimitrios L. Wagner, Timothy Davis, Rayne H. Rouce, Gang Bao, Malcolm K. Brenner, Maksim Mamonkin

    Gepubliceerd in 2017
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  8. 8
    CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients

    CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients door Leila Amini, Dimitrios L. Wagner, Uta Rössler, Ghazaleh Zarrinrad, Livia Felicitas Wagner, Tino Vollmer, Désirée J. Wendering, Uwe Kornak, Hans‐Dieter Volk, Petra Reinke, Michael Schmueck‐Henneresse

    Gepubliceerd in 2020
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  9. 9
    Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

    Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells door Viktor Glaser, Christian Flugel, Jonas Kath, Weijie Du, Vanessa Drosdek, Clemens Franke, Maik Stein, Axel Pruß, Michael Schmueck‐Henneresse, Hans‐Dieter Volk, Petra Reinke, Dimitrios L. Wagner

    Gepubliceerd in 2023
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  10. 10
    Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

    Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9 door Michael C. Gundry, Lorenzo Brunetti, Angelique Lin, Allison Mayle, Ayumi Kitano, Dimitrios L. Wagner, Joanne I. Hsu, Kevin A. Hoegenauer, Cliona M. Rooney, Margaret A. Goodell, Daisuke Nakada

    Gepubliceerd in 2016
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  11. 11
    Immunogenicity of CAR T cells in cancer therapy

    Immunogenicity of CAR T cells in cancer therapy door Dimitrios L. Wagner, Enrico Fritsche, Michael A. Pulsipher, Nabil Ahmed, Mohamad Hamieh, Meenakshi Hegde, Marco Ruella, Barbara Savoldo, Nirali N. Shah, Cameron J. Turtle, Alan S. Wayne, Mohamed Abou‐El‐Enein

    Gepubliceerd in 2021
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  12. 12
    Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells

    Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells door Thomas Shum, Bilal Omer, Haruko Tashiro, Robert L. Kruse, Dimitrios L. Wagner, Kathan Parikh, Zhongzhen Yi, Tim Sauer, Daofeng Liu, Robin Parihar, Paul Castillo, Hao Liu, Malcolm K. Brenner, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney

    Gepubliceerd in 2017
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  13. 13
    Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer

    Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer door Weijie Du, Fatih Noyan, Oliver McCallion, Vanessa Drosdek, Jonas Kath, Viktor Glaser, Carla Fuster‐García, Mingxing Yang, Maik Stein, Clemens Franke, Yundan Pu, Olaf Weber, Julia K. Polansky, Toni Cathomen, Elmar Jaeckel, Joanna Hester, Fadi Issa, Hans‐Dieter Volk, Michael Schmueck‐Henneresse, Petra Reinke, Dimitrios L. Wagner

    Gepubliceerd in 2025
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  14. 14
    Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial

    Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial door Andy Roemhild, Natalie Otto, Guido Moll, Mohamed Abou‐El‐Enein, Daniel R. Kaiser, Gantuja Bold, Thomas Schachtner, Mira Choi, Robert Oellinger, Sybille Landwehr-Kenzel, Karsten Juerchott, Birgit Sawitzki, Cordula Giesler, Anett Sefrin, Carola Beier, Dimitrios L. Wagner, Stephan Schlickeiser, Mathias Streitz, Michael Schmueck‐Henneresse, Leila Amini, Ulrik Stervbo, Nina Babel, Hans‐Dieter Volk, Petra Reinke

    Gepubliceerd in 2020
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  15. 15
    Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells

    Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells door Jonas Kath, Weijie Du, Alina Pruene, Tobias Braun, Bernice Thommandru, Rolf Turk, Morgan Sturgeon, Gavin Kurgan, Leila Amini, Maik Stein, Tatiana Zittel, Stefania Martini, Lennard Ostendorf, Andreas Wilhelm, Levent Akyüz, Armin Rehm, Uta E. Höpken, Axel Pruß, Annette Künkele, Ashley M. Jacobi, Hans‐Dieter Volk, Michael Schmueck‐Henneresse, Renata Stripecke, Petra Reinke, Dimitrios L. Wagner

    Gepubliceerd in 2022
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  16. 16
    Integration of <i>ζ</i>-deficient CARs into the <i>CD3</i> <i>ζ</i> gene conveys potent cytotoxicity in T and NK cells

    Integration of <i>ζ</i>-deficient CARs into the <i>CD3</i> <i>ζ</i> gene conveys potent cytotoxicity in T and NK cells door Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster‐García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E. Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou‐El‐Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans‐Dieter Volk, Petra Reinke, Michael Schmueck‐Henneresse, Dimitrios L. Wagner

    Gepubliceerd in 2024
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  17. 17
    CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression

    CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression door Kristen Fousek, Junji Watanabe, Sujith K. Joseph, Ann George, Xingyue An, Tiara T. Byrd, Jessica S. Morris, Annie Luong, Melisa Martinez-Paniagua, Khaled Sanber, Shoba A. Navai, Ahmed Z. Gad, Vita S. Salsman, Pretty Mathew, Hye Na Kim, Dimitrios L. Wagner, Lorenzo Brunetti, Albert Jang, Matthew L. Baker, Navin Varadarajan, Meenakshi Hegde, Yong‐Mi Kim, Nora Heisterkamp, Hisham Abdel‐Azim, Nabil Ahmed

    Gepubliceerd in 2020
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