檢索結果 - Dean C. Pavlick

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  1. 1
    Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumors

    Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumors 由 Darren Sigal, Munveer S. Bhangoo, Jonathan A. Hermel, Dean C. Pavlick, Garrett M. Frampton, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali

    出版 2018
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  2. 2
    Pan-Cancer Analysis of <i>CDK12</i> Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype

    Pan-Cancer Analysis of <i>CDK12</i> Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype 由 Ethan Sokol, Dean C. Pavlick, Garrett M. Frampton, Jeffrey S. Ross, Vincent A. Miller, Siraj M. Ali, Tamara L. Lotan, Drew M. Pardoll, Jon Chung, Emmanuel S. Antonarakis

    出版 2019
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  3. 3
    Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib

    Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib 由 Victor Wong, Dean C. Pavlick, Timothy J. Brennan, Roman Yelensky, John R. Crawford, Jeffrey S. Ross, Vincent A. Miller, Denise Malicki, Philip J. Stephens, Siraj M. Ali, Hyunah Ahn

    出版 2015
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  4. 4
    Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles

    Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles 由 Erik A. Williams, Nikunj Shah, Meagan Montesion, Radwa Sharaf, Dean C. Pavlick, Ethan Sokol, Brian M. Alexander, J. Venstrom, Julia A. Elvin, Jeffrey S. Ross, Julie Y. Tse, Mark C. Mochel

    出版 2020
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  5. 5
    Pan-Cancer Analysis of <i>BRCA1</i> and <i>BRCA2</i> Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity

    Pan-Cancer Analysis of <i>BRCA1</i> and <i>BRCA2</i> Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity 由 Ethan S. Sokol, Dean C. Pavlick, Hossein Khiabanian, Garrett M. Frampton, Jeffrey S. Ross, Jeffrey P. Gregg, Primo N. Lara, Steffi Oesterreich, Neeraj Agarwal, Andrea Necchi, Vincent A. Miller, Brian M. Alexander, Siraj M. Ali, Shridar Ganesan, Jon Chung

    出版 2020
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  6. 6
    738P Penile squamous cell carcinoma with high and very high tumor mutational burden (TMB): A genomic landscape and "real-world" clinical outcome study

    738P Penile squamous cell carcinoma with high and very high tumor mutational burden (TMB): A genomic landscape and "real-world" clinical outcome study 由 Joseph M Jacob, Philippe E. Spiess, T.C.D. Padua, Ruichao Li, Petros Grivas, Richard Huang, D.I. Lin, Natalie Danziger, Jeffrey S. Ross, G. Li, Ryon P. Graf, Dean C. Pavlick, Alina Basnet, Gennady Bratslavsky, Andrea Necchi

    出版 2023
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  7. 7
    Tumor Fraction Correlates With Detection of Actionable Variants Across &gt; 23,000 Circulating Tumor DNA Samples

    Tumor Fraction Correlates With Detection of Actionable Variants Across &gt; 23,000 Circulating Tumor DNA Samples 由 Hatim Husain, Dean C. Pavlick, Bernard J. Fendler, Russell W. Madison, Brennan Decker, Ole Gjoerup, Christine A. Parachoniak, Molly McLaughlin-Drubin, Rachel Erlich, Alexa B. Schrock, Garrett M. Frampton, Meghna Das Thakur, Geoffrey R. Oxnard, Hanna Tukachinsky

    出版 2022
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  8. 8
    Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Non–Small Cell Lung Cancer

    Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Non–Small Cell Lung Cancer 由 Alexa B. Schrock, Allison W. Welsh, Jon Chung, Dean C. Pavlick, Eric Bernicker, Ben Creelan, Brady Forcier, Jeffrey S. Ross, Philip J. Stephens, Siraj M. Ali, Ibiayi Dagogo‐Jack, Alice T. Shaw, Tianhong Li, Sai‐Hong Ignatius Ou, Vincent A. Miller

    出版 2018
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  9. 9
    Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational Burden

    Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational Burden 由 Andrea Necchi, Philippe E. Spiess, Tiago Costa de Pádua, Roger Li, Petros Grivas, Richard S.P. Huang, Douglas I. Lin, Natalie Danziger, Jeffrey S. Ross, Joseph M Jacob, Rebecca Sager, Alina Basnet, Gerald Li, Ryon P. Graf, Dean C. Pavlick, Gennady Bratslavsky

    出版 2023
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  10. 10
    Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types

    Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types 由 Pashtoon Murtaza Kasi, Jessica Lee, Lincoln W. Pasquina, Brennan Decker, Pierre Vanden Borre, Dean C. Pavlick, Justin M. Allen, Christine A. Parachoniak, Júlia C.F. Quintanilha, Ryon P. Graf, Alexa B. Schrock, Geoffrey R. Oxnard, Christine M. Lovly, Hanna Tukachinsky, Vivek Subbiah

    出版 2023
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  11. 11
    Methylthioadenosine Phosphorylase Genomic Loss in Advanced Gastrointestinal Cancers

    Methylthioadenosine Phosphorylase Genomic Loss in Advanced Gastrointestinal Cancers 由 Natalie Ngoi, Tin‐Yun Tang, Catia Fava Gaspar, Dean C. Pavlick, Gregory M. Buchold, Emma L. Scholefield, Vamsi Parimi, Richard S.P. Huang, Tyler Janovitz, Natalie Danziger, Mia Levy, Shubham Pant, Anaemy Danner De Armas, David Kumpula, Jeffrey S. Ross, Milind Javle, Jordi Rodón

    出版 2024
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  12. 12
    Identifying a Clinically Applicable Mutational Burden Threshold as a Potential Biomarker of Response to Immune Checkpoint Therapy in Solid Tumors

    Identifying a Clinically Applicable Mutational Burden Threshold as a Potential Biomarker of Response to Immune Checkpoint Therapy in Solid Tumors 由 Anshuman Panda, Anil Malleshi Betigeri, Kalyanasundaram Subramanian, Jeffrey S. Ross, Dean C. Pavlick, Siraj M. Ali, Paul Markowski, Ann W. Silk, Howard L. Kaufman, Edmund C. Lattime, Janice M. Mehnert, Ryan J. Sullivan, Christine M. Lovly, Jeffrey A. Sosman, Douglas B. Johnson, Gyan Bhanot, Shridar Ganesan

    出版 2017
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  13. 13
    Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting

    Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting 由 Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna C. Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean‐Nicolas Gallant, Yunkai Zhang, Yingjun Yan, Monica Red-Brewer, Siraj M. Ali, Alexa B. Schrock, Ahmet Zehir, Marc Ladanyi, Adam W. Smith, Jens Meiler, Christine M. Lovly

    出版 2021
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  14. 14
    Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

    Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer 由 Janice M. Mehnert, Anshuman Panda, Judy Zhong, Kim M. Hirshfield, Sherri Damare, Katherine Lane, Levi Sokol, Mark N. Stein, Lorna Rodriguez-Rodriquez, Howard L. Kaufman, Siraj M. Ali, Jeffrey S. Ross, Dean C. Pavlick, Gyan Bhanot, Eileen White, Robert S. DiPaola, Ann Lovell, Jonathan D. Cheng, Shridar Ganesan

    出版 2016
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  15. 15
    Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

    Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer 由 Smruthy Sivakumar, Dexter X. Jin, Hanna Tukachinsky, Karthikeyan Murugesan, Kimberly McGregor, Natalie Danziger, Dean C. Pavlick, Ole Gjoerup, Jeffrey S. Ross, Robert J. Harmon, Jon Chung, Brennan Decker, Lucas Dennis, Garrett M. Frampton, Luciana Molinero, Steffi Oesterreich, Jeffrey M. Venstrom, Geoffrey R. Oxnard, Priti S. Hegde, Ethan Sokol

    出版 2022
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  16. 16
    Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus

    Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus 由 Alexa B. Schrock, Dean C. Pavlick, Samuel J. Klempner, Jon Chung, Brady Forcier, Allison W. Welsh, Lauren Young, B Leyland-Jones, Rodolfo Bordoni, Richard D. Carvajal, Joseph Chao, Razelle Kurzrock, Jason K. Sicklick, Jeffrey S. Ross, Philip J. Stephens, Craig Devoe, Fadi Braiteh, Siraj M. Ali, Vincent A. Miller

    出版 2018
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  17. 17
    PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib

    PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib 由 Anna Bianchi, Salvatore Lopez, Gary Altwerger, Stefania Bellone, Elena Bonazzoli, Luca Zammataro, Aránzazu Manzano, Paola Manara, Emanuele Perrone, Burak Zeybek, Chanhee Han, Gulden Menderes, Elena Ratner, Dan‐Arin Silasi, Gloria S. Huang, Masoud Azodi, Justin Y. Newberg, Dean C. Pavlick, Julia A. Elvin, Garrett M. Frampton, Peter E. Schwartz, Alessandro D. Santin

    出版 2019
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  18. 18
    Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response

    Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response 由 Meagan Montesion, Karthikeyan Murugesan, Dexter X. Jin, Radwa Sharaf, Nora Sánchez, Ameet Guria, Max Minker, Gerald Li, Virginia Fisher, Ethan S. Sokol, Dean C. Pavlick, Jay A. Moore, Alan Braly, Gaurav Singal, David Fabrizio, Leah A. Comment, Naiyer A. Rizvi, Brian M. Alexander, Garrett M. Frampton, Priti S. Hegde, Lee A. Albacker

    出版 2020
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  19. 19
    Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors

    Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors 由 Coren A. Milbury, James Creeden, Wai‐Ki Yip, David L. Smith, Varun P. Pattani, Kristi Maxwell, Bethany Sawchyn, Ole Gjoerup, Wei Meng, Joel Skoletsky, Alvin D. Concepcion, Yanhua Tang, Xiaobo Bai, Ninad Dewal, Pei Ma, Shannon T. Bailey, James E. Thornton, Dean C. Pavlick, Garrett M. Frampton, Daniel S. Lieber, Jared White, Christine Burns, Christine Vietz

    出版 2022
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  20. 20
    Vulvar Squamous Cell Carcinoma: Comprehensive Genomic Profiling of HPV+ Versus HPV– Forms Reveals Distinct Sets of Potentially Actionable Molecular Targets

    Vulvar Squamous Cell Carcinoma: Comprehensive Genomic Profiling of HPV+ Versus HPV– Forms Reveals Distinct Sets of Potentially Actionable Molecular Targets 由 Erik A. Williams, Adrienne Werth, Radwa Sharaf, Meagan Montesion, Ethan S. Sokol, Dean C. Pavlick, Molly McLaughlin-Drubin, Rachel Erlich, Helen Toma, Kevin Jon Williams, J. Venstrom, Brian M. Alexander, Nikunj Shah, Natalie Danziger, Amanda Hemmerich, Eric A. Severson, Jonathan Keith Killian, Douglas I. Lin, Jeffrey S. Ross, Julie Y. Tse, Shakti Ramkissoon, Mark C. Mochel, Julia A. Elvin

    出版 2020
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