Søgeresultater - David Santamarı́a

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  1. 1
    Cyclins and CDKS in development and cancer: lessons from genetically modified mice

    Cyclins and CDKS in development and cancer: lessons from genetically modified mice af David Santamarı́a

    Udgivet 2006
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  2. 2
    Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6

    Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6 af Elizabeth J. Hennessy, Frederick J. Sheedy, David Santamarı́a, Mariano Barbacid, Luke O'neill

    Udgivet 2011
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  3. 3
    Overall Cdk activity modulates the DNA damage response in mammalian cells

    Overall Cdk activity modulates the DNA damage response in mammalian cells af Antonio Cerqueira, David Santamarı́a, Bárbara Martínez-Pastor, Myriam Cuadrado, Óscar Fernández-Capetillo, Mariano Barbacid

    Udgivet 2009
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  4. 4
    Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6

    Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6 af Marcos Malumbres, Rocı́o Sotillo, David Santamarı́a, Javier Galán, Ana Cerezo, Sagrario Ortega, Pierre Dubus, Mariano Barbacid

    Udgivet 2004
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  5. 5
    c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma

    c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma af Rafael B. Blasco, Sarah Francoz, David Santamarı́a, Marta Cañamero, Pierre Dubus, Jean Charron, Manuela Baccarini, Mariano Barbacid

    Udgivet 2011
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  6. 6
    A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

    A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma af Marta Puyol, Alberto Martín, Pierre Dubus, Francisca Mulero, Pilar Pizcueta, Gulfaraz Khan, Carmen Guerra, David Santamarı́a, Mariano Barbacid

    Udgivet 2010
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  7. 7
    Mice thrive without Cdk4 and Cdk2

    Mice thrive without Cdk4 and Cdk2 af Cédric Barrière, David Santamarı́a, Antonio Cerqueira, Javier Galán, Alberto Martín, Sagrario Ortega, Marcos Malumbres, Pierre Dubus, Mariano Barbacid

    Udgivet 2007
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  8. 8
    Cdk6-Dependent Regulation of G1 Length Controls Adult Neurogenesis

    Cdk6-Dependent Regulation of G1 Length Controls Adult Neurogenesis af Pierre Beukelaers, Renaud Vandenbosch, Nicolas Caron, Laurent Nguyen, Shibeshih Belachew, Gustave Moonen, Hiroaki Kiyokawa, Mariano Barbacid, David Santamarı́a, Brigitte Malgrange

    Udgivet 2011
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  9. 9
    Functional Reprogramming of Polyploidization in Megakaryocytes

    Functional Reprogramming of Polyploidization in Megakaryocytes af Marianna Trakala, Sara Rodríguez‐Acebes, María Maroto, Catherine E. Symonds, David Santamarı́a, Sagrario Ortega, Mariano Barbacid, Juan Méndez, Marcos Malumbres

    Udgivet 2015
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  10. 10
    CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase

    CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase af Alberto Viera, Manfred Alsheimer, Rocío Gómez, Inés Berenguer, Sagrario Ortega, Catherine E. Symonds, David Santamarı́a, Ricardo Benavente, José Á. Suja

    Udgivet 2014
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  11. 11
    Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion

    Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion af Miguel Ganuza, Cristina Sáiz-Ladera, Marta Cañamero, Gonzalo Goméz-López, Ralph P. Schneider, Marı́a A. Blasco, David G. Pisano, Jesús M. Paramio, David Santamarı́a, Mariano Barbacid

    Udgivet 2012
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  12. 12
    A Braf kinase-inactive mutant induces lung adenocarcinoma

    A Braf kinase-inactive mutant induces lung adenocarcinoma af Patricia Nieto, Chiara Ambrogio, Laura Esteban-Burgos, Gonzalo Goméz-López, Maria Blasco, Zhan Yao, Richard Marais, Neal Rosen, Roberto Chiarle, David G. Pisano, Mariano Barbacid, David Santamarı́a

    Udgivet 2017
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  13. 13
    Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27

    Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 af Lucía García-Gutiérrez, Gabriel Bretones, Ester Molina, Ignacio Aréchaga, Catherine E. Symonds, Juan Carlos Acosta, Rosa Blanco, Adrián Fernández, Leticia Alonso, Piotr Siciński, Mariano Barbacid, David Santamarı́a, Javier León

    Udgivet 2019
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  14. 14
    Oncogenic mutant <scp>KRAS</scp> inhibition through oxidation at cysteine 118

    Oncogenic mutant <scp>KRAS</scp> inhibition through oxidation at cysteine 118 af Maximilian Kramer‐Drauberg, Ettore Petrini, Alessia Mira, Enrico Patrucco, Rossella Scardaci, Ilenia Savinelli, Haiyun Wang, Keying Qiao, Giovanna Carrà, Marie‐Julie Nokin, Zhiwei Zhou, Kenneth D. Westover, David Santamarı́a, Paolo E. Porporato, Chiara Ambrogio

    Udgivet 2025
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  15. 15
    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS af Chiara Ambrogio, Jens Köhler, Zhi-Wei Zhou, Haiyun Wang, Raymond M. Paranal, Jiaqi Li, Marzia Capelletti, Cristina Caffarra, Shuai Li, Qi Lv, Sudershan Reddy Gondi, John C. Hunter, Jia Lu, Roberto Chiarle, David Santamarı́a, Kenneth D. Westover, Pasi A. Jänne

    Udgivet 2018
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  16. 16
    Genetic evidence for patrilocal mating behavior among Neandertal groups

    Genetic evidence for patrilocal mating behavior among Neandertal groups af Carles Lalueza‐Fox, Antonio Rosas, Almudena Estalrrich, Elena Gigli, Paula F. Campos, Antonio García‐Tabernero, Samuel García‐Vargas, Federico Sánchez‐Quinto, Óscar Ramírez, Sergi Civit, Markus Bastir, Rosa Huguet, David Santamaría Álvarez, M. Thomas P. Gilbert, Eske Willerslev, Marco de la Rasilla Vives

    Udgivet 2010
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  17. 17
    Cell cycle duration determines oncogenic transformation capacity

    Cell cycle duration determines oncogenic transformation capacity af Danian Chen, Suying Lü, Katherine Huang, Joel D. Pearson, Marek Pacal, Philippos Peidis, Sean R. McCurdy, Tao Yu, Monika Sangwan, Angela Nguyen, Philippe P. Monnier, Daniel Schramek, Liang Zhu, David Santamarı́a, Mariano Barbacid, Nagako Akeno, Kathryn A. Wikenheiser‐Brokamp, Rod Bremner

    Udgivet 2025
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  18. 18
    RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade

    RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade af Marie‐Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin, Isabelle Soubeyran, Sonia San José, Serena Peirone, Livia Caizzi, Sandra Vietti Michelina, Aurélien Bourdon, Xinan Wang, Daniel Alvarez-Villanueva, María Martínez‐Iniesta, August Vidal, Telmo Rodrigues, María Carmen García-Macías, Mark M. Awad, Ernest Nadal, Alberto Villanueva, Antoîne Italiano, Matteo Cereda, David Santamarı́a, Chiara Ambrogio

    Udgivet 2024
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  19. 19
    Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of<i>KRAS</i>Mutations in Non–Small Cell Lung Cancer

    Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of<i>KRAS</i>Mutations in Non–Small Cell Lung Cancer af Biagio Ricciuti, Jieun Son, Jeffrey J. Okoro, Alessia Mira, Enrico Patrucco, Yoonji Eum, Xinan Wang, Raymond M. Paranal, Haiyun Wang, Mika Lin, Heidi M. Haikala, Jiaqi Li, Yue Xu, Joao V. Alessi, Chhayheng Chhoeu, Amanda J. Redig, Jens Köhler, Kshiti H. Dholakia, Yunhan Chen, Élodie Richard, Marie‐Julie Nokin, David Santamarı́a, Prafulla C. Gokhale, Mark M. Awad, Pasi A. Jänne, Chiara Ambrogio

    Udgivet 2022
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  20. 20
    Reuniting philosophy and science to advance cancer research

    Reuniting philosophy and science to advance cancer research af Thomas Pradeu, Bertrand Daignan‐Fornier, Andrew J. Ewald, Pierre‐Luc Germain, Samir Okasha, Anya Plutynski, Sébastien Benzekry, Marta Bertolaso, Mina J. Bissell, Joel S. Brown, Benjamin Chin‐Yee, Ian Chin‐Yee, Hans Clevers, Laurent Cognet, Marie Darrason, Emmanuel Farge, Jean Feunteun, Jérôme Galon, Élodie Giroux, Sara Green, Fridolin Groß, Fanny Jaulin, Rob Knight, Ezio Laconi, Nicolas Larmonier, Carlo C. Maley, Alberto Mantovani, Violaine Moreau, Pierre Nassoy, Elena Rondeau, David Santamarı́a, Catherine M. Sawai, Andrei Seluanov, Gregory D. Sepich‐Poore, Vanja Sisirak, Éric Solary, Sarah Yvonnet, Lucie Laplane

    Udgivet 2023
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