Zoekresultaten - David R. Spring

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  1. 1
    Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

    Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions door Naomi Robertson, David R. Spring

    Gepubliceerd in 2018
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  2. 2
    Tryptophan in Multicomponent Petasis Reactions for Peptide Stapling and Late‐Stage Functionalisation

    Tryptophan in Multicomponent Petasis Reactions for Peptide Stapling and Late‐Stage Functionalisation door Soňa Krajčovičová, David R. Spring

    Gepubliceerd in 2023
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  3. 3
    Non-internalising antibody–drug conjugates

    Non-internalising antibody–drug conjugates door Nicola Ashman, Jonathan D. Bargh, David R. Spring

    Gepubliceerd in 2022
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  4. 4
    The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations

    The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations door Yaw Sing Tan, David R. Spring, Chris Abell, Chandra Verma

    Gepubliceerd in 2014
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  5. 5
    Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

    Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules door Warren R. J. D. Galloway, Albert Isidro‐Llobet, David R. Spring

    Gepubliceerd in 2010
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  6. 6
    A new Pseudomonas quinolone signal (PQS) binding partner: MexG

    A new Pseudomonas quinolone signal (PQS) binding partner: MexG door James T. Hodgkinson, Jeremy Gross, Ysobel R. Baker, David R. Spring, Martin Welch

    Gepubliceerd in 2016
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  7. 7
    A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium

    A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium door Joshua P. Ramsay, Neil R. Williamson, David R. Spring, George P. C. Salmond

    Gepubliceerd in 2011
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  8. 8
    The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions

    The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions door Bee‐Ha Gan, Josephine Gaynord, Sam M. Rowe, Tomáš Deingruber, David R. Spring

    Gepubliceerd in 2021
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  9. 9
    Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

    Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections door Sarah L. Kidd, Thomas J. Osberger, Natalia Mateu, Hannah F. Sore, David R. Spring

    Gepubliceerd in 2018
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  10. 10
    Strategies for the Diversity-Oriented Synthesis of Macrocycles

    Strategies for the Diversity-Oriented Synthesis of Macrocycles door Kim T. Mortensen, Thomas J. Osberger, Thomas A. King, Hannah F. Sore, David R. Spring

    Gepubliceerd in 2019
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  11. 11
    Peptides as a platform for targeted therapeutics for cancer: peptide–drug conjugates (PDCs)

    Peptides as a platform for targeted therapeutics for cancer: peptide–drug conjugates (PDCs) door Bethany Cooper, Jessica Iegre, Daniel H. O’Donovan, Maria Ölwegård Halvarsson, David R. Spring

    Gepubliceerd in 2020
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  12. 12
    Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

    Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions door Luca Laraia, Grahame J. McKenzie, David R. Spring, Ashok R. Venkitaraman, David J. Huggins

    Gepubliceerd in 2015
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  13. 13
    Communications blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing?

    Communications blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing? door Declan M. Roche, Joseph T. Byers, Debra S. Smith, Freija G. Glansdorp, David R. Spring, Martin Welch

    Gepubliceerd in 2004
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  14. 14
    Loving the poison: the methylcitrate cycle and bacterial pathogenesis

    Loving the poison: the methylcitrate cycle and bacterial pathogenesis door Stephen K. Dolan, Andre Wijaya, Stephen M. Geddis, David R. Spring, Rafael Silva‐Rocha, Martin Welch

    Gepubliceerd in 2018
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  15. 15
    Sulfatase-cleavable linkers for antibody-drug conjugates

    Sulfatase-cleavable linkers for antibody-drug conjugates door Jonathan D. Bargh, Stephen J. Walsh, Albert Isidro‐Llobet, Soleilmane Omarjee, Jason S. Carroll, David R. Spring

    Gepubliceerd in 2020
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  16. 16
    Metabolic and regulatory engineering of Serratia marcescens: mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum-sensing capacities

    Metabolic and regulatory engineering of Serratia marcescens: mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum-sensing capacities door Sarah J. Coulthurst, Neil R. Williamson, Abigail K. P. Harris, David R. Spring, George P. C. Salmond

    Gepubliceerd in 2006
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  17. 17
    Peroxide-cleavable linkers for antibody–drug conjugates

    Peroxide-cleavable linkers for antibody–drug conjugates door Nicola Ashman, Jonathan D. Bargh, Stephen J. Walsh, Ryan Greenwood, Arnaud Tiberghien, Jason S. Carroll, David R. Spring

    Gepubliceerd in 2023
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  18. 18
    Using Ligand‐Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo‐Like Kinase 1

    Using Ligand‐Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo‐Like Kinase 1 door Yaw Sing Tan, P. Sledz, Steffen Lang, Christopher J. Stubbs, David R. Spring, Chris Abell, Robert B. Best

    Gepubliceerd in 2012
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  19. 19
    A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066

    A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066 door Claudia De Fusco, P. Brear, Jessica Iegre, Kathy Hadje Georgiou, Hannah F. Sore, Marko Hyvönen, David R. Spring

    Gepubliceerd in 2017
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  20. 20
    Towards the Targeted Protein Degradation of PRMT1

    Towards the Targeted Protein Degradation of PRMT1 door Poppy L. Martin, F. Javier Pérez-Areales, Shalini V. Rao, Stephen J. Walsh, Jason S. Carroll, David R. Spring

    Gepubliceerd in 2024
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