Resultados da pesquisa - David K. Chang

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  1. 1
    Pancreatic Cancer Genomes: Implications for Clinical Management and Therapeutic Development

    Pancreatic Cancer Genomes: Implications for Clinical Management and Therapeutic Development Por Stephan Dreyer, David K. Chang, Peter J. Bailey, Andrew V. Biankin

    Publicado em 2017
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  2. 2
    Molecular Subtyping and Precision Medicine for Pancreatic Cancer

    Molecular Subtyping and Precision Medicine for Pancreatic Cancer Por Fieke E. M. Froeling, Raffaella Casolino, Antonio Pea, Andrew V. Biankin, David K. Chang

    Publicado em 2021
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  3. 3
    Defining the molecular pathology of pancreatic body and tail adenocarcinoma

    Defining the molecular pathology of pancreatic body and tail adenocarcinoma Por Stephan Dreyer, Nigel B. Jamieson, Rosanna Upstill‐Goddard, Peter J. Bailey, C. McKay, Andrew V. Biankin, David K. Chang

    Publicado em 2018
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  4. 4
    BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer

    BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer Por Michael J. Pishvaian, Andrew V. Biankin, Peter J. Bailey, David K. Chang, Daniel A. Laheru, Christopher L. Wolfgang, Jonathan R. Brody

    Publicado em 2017
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  5. 5
    Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine

    Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine Por Raffaella Casolino, Chiara Braconi, Giuseppe Malleo, Salvatore Paiella, Claudio Bassi, Michèle Milella, Stephan Dreyer, Fieke E. M. Froeling, David K. Chang, Andrew V. Biankin, Talia Golan

    Publicado em 2020
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  6. 6
    Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin

    Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin Por PamelaSara E. Head, Sangho Myung, Yong Chen, Jessica L. Schneller, Cindy Wang, Nicholas R. Duncan, Pauline R. Hoffman, David K. Chang, Abigael Gebremariam, Marjan Guček, Irini Manoli, Charles P. Venditti

    Publicado em 2022
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  7. 7
    Recruitment and Activation of Pancreatic Stellate Cells from the Bone Marrow in Pancreatic Cancer: A Model of Tumor-Host Interaction

    Recruitment and Activation of Pancreatic Stellate Cells from the Bone Marrow in Pancreatic Cancer: A Model of Tumor-Host Interaction Por Christopher J. Scarlett, Emily K. Colvin, Mark Pinese, David K. Chang, Adrienne Morey, Elizabeth A. Musgrove, Marina Pajic, Minoti V. Apte, Susan M. Henshall, Robert L. Sutherland, James G. Kench, Andrew V. Biankin

    Publicado em 2011
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  8. 8
    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways

    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways Por Hnin Ei Ei Khine, Utid Suriya, Thanyada Rungrotmongkol, Supakarn Chamni, Yanxi Lu, Alan Bénard, Bin Lan, Debabrata Mukhopadhyay, David K. Chang, Andrew V. Biankin, Regine Schneider‐Stock, Robert Grützmann, Rungroch Sungthong, Christian Pilarsky, Chatchai Chaotham

    Publicado em 2025
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  9. 9
    Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin

    Neuropilin-2 Promotes Extravasation and Metastasis by Interacting with Endothelial α5 Integrin Por Ying Cao, Luke H. Hoeppner, Steven Bach, E Guangqi, Yan Guo, Enfeng Wang, Jianmin Wu, Mark J. Cowley, David K. Chang, Nicola Waddell, Sean M. Grimmond, Andrew V. Biankin, Roger J. Daly, Xiao Hui Zhang, Debabrata Mukhopadhyay

    Publicado em 2013
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  10. 10
    Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

    Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma Por Peter J. Bailey, David K. Chang, Marie‐Andrée Forget, F. Anthony San Lucas, Hector A. Alvarez, Cara Haymaker, Chandrani Chattopadhyay, Sun-Hee Kim, Sühendan Ekmekçioğlu, Elizabeth A. Grimm, Andrew V. Biankin, Patrick Hwu, Anirban Maitra, Jason Roszik

    Publicado em 2016
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  11. 11
    Feasibility and clinical utility of endoscopic ultrasound guided biopsy of pancreatic cancer for next-generation molecular profiling

    Feasibility and clinical utility of endoscopic ultrasound guided biopsy of pancreatic cancer for next-generation molecular profiling Por Stephan Dreyer, Nigel B. Jamieson, Lisa Evers, Fraser R. Duthie, Susie Cooke, John L. Marshall, Dario Beraldi, Stephen R Knight, Rosanna Upstill‐Goddard, Euan J. Dickson, C. Ross Carter, Colin J. McKay, Andrew V. Biankin, David K. Chang

    Publicado em 2019
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  12. 12
    Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

    Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma Por Michael E. Feigin, Tyler H. Garvin, Peter J. Bailey, Nicola Waddell, David K. Chang, David R. Kelley, Shimin Shuai, Steven Gallinger, John D. McPherson, Sean M. Grimmond, Ekta Khurana, Lincoln Stein, Andrew V. Biankin, Michael C. Schatz, David A. Tuveson

    Publicado em 2017
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  13. 13
    Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis

    Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis Por Raffaella Casolino, Salvatore Paiella, Danila Azzolina, Philip Beer, Vincenzo Corbo, Giulia Lorenzoni, Darío Gregori, Talia Golan, Chiara Braconi, Fieke E. M. Froeling, Michèle Milella, Aldo Scarpa, Antonio Pea, Giuseppe Malleo, Roberto Salvia, Claudio Bassi, David K. Chang, Andrew V. Biankin

    Publicado em 2021
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  14. 14
    ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer

    ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer Por Rowan Miller, Alexandra Léary, Clare L. Scott, Violeta Serra, Christopher J. Lord, David D.L. Bowtell, David K. Chang, Dale W. Garsed, Jos Jonkers, Jonathan A. Ledermann, Serena Nik‐Zainal, Isabelle Ray‐Coquard, Sohrab P. Shah, Xavier Matías‐Guiu, Elizabeth M. Swisher, Lucy Yates

    Publicado em 2020
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  15. 15
    Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

    Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects Por Glenn M. Marshall, Samuele Gherardi, Ning Xu, Zillan Neiron, Toby N. Trahair, Christopher J. Scarlett, David K. Chang, Peiyuan Liu, Kacper Jankowski, Nunzio Iraci, Michelle Haber, Murray D. Norris, Joanna Keating, Eric Sekyere, Georg von Jonquières, Fabio Stossi, Benita S. Katzenellenbogen, Andrew V. Biankin, Giovanni Perini, Tao Liu

    Publicado em 2010
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  16. 16
    Adjuvant chemotherapy in elderly patients with pancreatic cancer

    Adjuvant chemotherapy in elderly patients with pancreatic cancer Por Adnan Nagrial, David K. Chang, Nam Q. Nguyen, Amber L. Johns, Lorraine A. Chantrill, Jeremy L. Humphris, Venessa Chin, Jaswinder S. Samra, Anthony J. Gill, Marina Pajic, Mark Pinese, Emily K. Colvin, Christopher J. Scarlett, Angela Chou, James G. Kench, R. L. Sutherland, Lisa G. Horvath, Andrew V. Biankin

    Publicado em 2013
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  17. 17
    PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance

    PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance Por Nilotpal Roy, Kenneth K. Takeuchi, Jeanine Ruggeri, Peter J. Bailey, David K. Chang, Joey H. Li, Laura Leonhardt, Sapna Puri, Megan T. Hoffman, Shan Gao, Christopher J. Halbrook, Yan Song, Mats Ljungman, Shivani Malik, Christopher V.E. Wright, David W. Dawson, Andrew V. Biankin, Matthias Hebrok, Howard C. Crawford

    Publicado em 2016
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  18. 18
    Study protocol: multi-centre, randomised controlled clinical trial exploring stromal targeting in locally advanced pancreatic cancer; STARPAC2

    Study protocol: multi-centre, randomised controlled clinical trial exploring stromal targeting in locally advanced pancreatic cancer; STARPAC2 Por Hemant M. Kocher, Charlotte Ackerman, Garima Priyadarshini, Cheryl Lawrence, Nishtha Kotriwala, Ramona Georgescu, Rhiannon Roberts, Christine S. Hughes, Ahmet Imrali, Claude Chelala, Judith Dixon-Hughes, David K. Chang, Peter Sasieni, Pippa Corrie, Mairéad G. McNamara, Debashis Sarker, Fieke E. M. Froeling, Alan Christie, Roopinder Gillmore, Khurum Khan, David Propper

    Publicado em 2025
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  19. 19
    The prognostic and predictive value of serum CA19.9 in pancreatic cancer

    The prognostic and predictive value of serum CA19.9 in pancreatic cancer Por Jeremy L. Humphris, David K. Chang, Amber L. Johns, Christopher J. Scarlett, Marina Pajic, Marc D. Jones, Emily K. Colvin, Adnan Nagrial, Venessa Chin, Lorraine A. Chantrill, Jaswinder S. Samra, Anthony J. Gill, James G. Kench, Neil D. Merrett, Anibh M. Das, Elizabeth A. Musgrove, R. L. Sutherland, Andrew V. Biankin

    Publicado em 2012
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  20. 20
    <i>Sleeping Beauty</i> mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

    <i>Sleeping Beauty</i> mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma Por Karen M. Mann, Jerrold M. Ward, Christopher Chin Kuan Yew, Anne Kovochich, David W. Dawson, Michael A. Black, Benjamin T. Brett, Todd E. Sheetz, Adam J. Dupuy, David K. Chang, Andrew V. Biankin, Nicola Waddell, Karin S. Kassahn, Sean M. Grimmond, Alistair G. Rust, David J. Adams, Nancy A. Jenkins, Neal G. Copeland

    Publicado em 2012
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