نتائج البحث - David E. Timm
- يعرض 1 - 8 نتائج من 8
-
1
-
2
-
3
-
4
-
5
Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors حسب Bruce W. Konicek, Andrew Capen, Kelly M. Credille, Philip J. Ebert, Beverly L. Falcón, Gary L. Heady, Bharvin K.R. Patel, Victoria L. Peek, Jennifer R. Stephens, Julie Stewart, Stephanie L. Stout, David E. Timm, Suzane L. Um, Melinda D. Willard, Isabella H. Wulur, Yi Arial Zeng, Yong Wang, Richard A. Walgren, S. Betty Yan
منشور في 2018Artigo -
6
Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor حسب Patrick C. May, Robert A. Dean, Stephen L. Lowe, Ferenc Martényi, Scott M. Sheehan, Leonard N. Boggs, Scott A. Monk, Brian M. Mathes, Dustin J. Mergott, Brian M. Watson, Stephanie L. Stout, David E. Timm, Elizabeth LaBell, Celedon Gonzales, Masako Nakano, Stanford S. Jhee, Mark Yen, Larry Ereshefsky, Terry D. Lindstrom, David O. Calligaro, Patrick J. Cocke, Dennis G. Hall, Stuart Friedrich, Martin Citron, James E. Audia
منشور في 2011Artigo -
7
Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction حسب David C. McKinney, Brian J. McMillan, Matthew J. Ranaghan, Jamie A. Moroco, Merissa Brousseau, Zachary Mullin-Bernstein, Meghan O’Keefe, Patrick McCarren, Michael F. Mesleh, Kathleen M. Mulvaney, Foxy P. Robinson, Ritu Singh, Besnik Bajrami, Florence F. Wagner, Robert Hilgraf, Martin J. Drysdale, Arthur J. Campbell, Adam Skepner, David E. Timm, Dale Porter, Virendar K. Kaushik, William R. Sellers, Alessandra Ianari
منشور في 2021Artigo -
8
The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans حسب Patrick C. May, Brian A. Willis, Stephen L. Lowe, Robert A. Dean, Scott A. Monk, Patrick J. Cocke, James E. Audia, Leonard N. Boggs, Anthony R. Borders, Richard A. Brier, David O. Calligaro, Theresa A. Day, Larry Ereshefsky, Jon A. Erickson, Hykop Gevorkyan, Celedon Gonzales, Douglas E. James, Stanford S. Jhee, Steven F. Komjathy, Lin Li, Terry D. Lindstrom, Brian M. Mathes, Ferenc Martényi, Scott M. Sheehan, Stephanie L. Stout, David E. Timm, Grant M. Vaught, Brian M. Watson, Leonard L. Winneroski, Zhixiang Yang, Dustin J. Mergott
منشور في 2015Artigo
أدوات البحث:
موضوعات ذات صلة
Biochemistry
Chemistry
Biology
Gene
Genetics
Internal medicine
Medicine
Stereochemistry
Alzheimer's disease
Amyloid (mycology)
Amyloid precursor protein
Amyloid precursor protein secretase
Crystallography
Dimer
Disease
Enzyme
Organic chemistry
Pathology
Pharmacology
Receptor
Recombinant DNA
Alkaptonuria
Antiretroviral therapy
Artificial intelligence
Barrel (horology)
Binding site
Bioinformatics
Biomarker
Biotechnology
Cancer