Ngā hua rapu kaituhi

1

Resources for the design of CRISPR gene editing experiments mā Daniel B. Graham, David E. Root

I whakaputaina 2015

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Revisão

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I tiakina i:
2

Identification of an oncogenic RAB protein mā Douglas B. Wheeler, Roberto Zoncu, David E. Root, David M. Sabatini, Charles L. Sawyers

I whakaputaina 2015

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
3

Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors mā Steven R. Whittaker, Glenn S. Cowley, Steve Wagner, Flora Luo, David E. Root, Levi A. Garraway

I whakaputaina 2015

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
4

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines mā Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova, Joshua Pan, Guillaume Kugener, David E. Root, Aviad Tsherniak

I whakaputaina 2019

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Pré-impressão

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I tiakina i:
5

Conserved pathways within bacteria and yeast as revealed by global protein network alignment mā Brian Kelley, Roded Sharan, Richard M. Karp, Taylor Sittler, David E. Root, Brent R. Stockwell, Trey Ideker

I whakaputaina 2003

Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
6

Mitochondrial and Nuclear Genomic Responses to Loss of LRPPRC Expression mā Vishal M. Gohil, Roland Nilsson, Casey A. Belcher-Timme, Biao Luo, David E. Root, Vamsi K. Mootha

I whakaputaina 2010

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
7

Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool mā Katherine Donovan, Mudra Hegde, Meagan E. Sullender, Emma W Vaimberg, Cory M. Johannessen, David E. Root, John G. Doench

I whakaputaina 2017

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
8

Receptor Tyrosine Kinases Fall into Distinct Classes Based on Their Inferred Signaling Networks mā Joel P. Wagner, Alejandro Wolf‐Yadlin, Mark Sevecka, Jennifer K. Grenier, David E. Root, Douglas A. Lauffenburger, Gavin MacBeath

I whakaputaina 2013

Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
9

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation mā Jason D. Arroyo, Alexis A. Jourdain, Sarah E. Calvo, Carmine Ballarano, John G. Doench, David E. Root, Vamsi K. Mootha

I whakaputaina 2016

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
10

Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression mā Joseph Rosenbluh, Han Xu, William F. Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn

I whakaputaina 2017

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
11

Chronos: a CRISPR cell population dynamics model mā Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

I whakaputaina 2021

Whiwhi kuputuhi katoa
Pré-impressão

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I tiakina i:
12

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects mā Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

I whakaputaina 2021

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
13

Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects mā Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark‐Anthony Bray, Federica Piccioni, David E. Root, John G. Doench, Jesse S. Boehm, Anne E. Carpenter

I whakaputaina 2015

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
14

A Genome-Scale RNA Interference Screen Implicates NF1 Loss in Resistance to RAF Inhibition mā Steven R. Whittaker, Jean‐Philippe Theurillat, Eliezer M. Van Allen, Nikhil Wagle, Jessica Hsiao, Glenn S. Cowley, Dirk Schadendorf, David E. Root, Levi A. Garraway

I whakaputaina 2013

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
15

High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons mā Thomas J.F. Nieland, David J. Logan, Jessica L. Saulnier, Daniel D. Lam, Caroline A. Johnson, David E. Root, Anne E. Carpenter, Bernardo L. Sabatini

I whakaputaina 2014

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
16

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells mā Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David Scott, Tarjei S. Mikkelsen, Dirk Heckl, Benjamin L. Ebert, David E. Root, John G. Doench, Feng Zhang

I whakaputaina 2013

Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
17

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways mā Michelle Dang, Nicole Armbruster, Miles A. Miller, Efraín A. Cermeño, Monika Hartmann, George W. Bell, David E. Root, Douglas A. Lauffenburger, Harvey F. Lodish, Andreas Herrlich

I whakaputaina 2013

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
18

CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines mā Daniel J. Merk, Linda Paul, Foteini Tsiami, Helen Hohenthanner, Ghazal Mohseni Kouchesfahani, Lara A. Haeusser, Bianca Walter, Adam Brown, Nicole S. Persky, David E. Root, Ghazaleh Tabatabai

I whakaputaina 2024

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
19

An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription mā Matthieu Giraud, Nada Jmari, Lina Du, Floriane Carallis, Thomas J.F. Nieland, Flor M. Pérez-Campo, Olivier Bensaude, David E. Root, Nir Hacohen, Diane Mathis, Christophe Benoist

I whakaputaina 2014

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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I tiakina i:
20

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen mā Benjamin L. Ebert, Jennifer Pretz, Jocelyn Bosco, Cindy Chang, Pablo Tamayo, Naomi Galili, Azra Raza, David E. Root, Eyal C. Attar, Steven R. Ellis, Todd R. Golub

I whakaputaina 2008

Whiwhi kuputuhi katoa
Artigo

Tiaki ki tētahi rārangi

I tiakina i:

Ngā hua rapu - David E. Root

Resources for the design of CRISPR gene editing experiments mā Daniel B. Graham, David E. Root

Identification of an oncogenic RAB protein mā Douglas B. Wheeler, Roberto Zoncu, David E. Root, David M. Sabatini, Charles L. Sawyers

Combined Pan-RAF and MEK Inhibition Overcomes Multiple Resistance Mechanisms to Selective RAF Inhibitors mā Steven R. Whittaker, Glenn S. Cowley, Steve Wagner, Flora Luo, David E. Root, Levi A. Garraway

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines mā Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova, Joshua Pan, Guillaume Kugener, David E. Root, Aviad Tsherniak

Conserved pathways within bacteria and yeast as revealed by global protein network alignment mā Brian Kelley, Roded Sharan, Richard M. Karp, Taylor Sittler, David E. Root, Brent R. Stockwell, Trey Ideker

Mitochondrial and Nuclear Genomic Responses to Loss of LRPPRC Expression mā Vishal M. Gohil, Roland Nilsson, Casey A. Belcher-Timme, Biao Luo, David E. Root, Vamsi K. Mootha

Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool mā Katherine Donovan, Mudra Hegde, Meagan E. Sullender, Emma W Vaimberg, Cory M. Johannessen, David E. Root, John G. Doench

Receptor Tyrosine Kinases Fall into Distinct Classes Based on Their Inferred Signaling Networks mā Joel P. Wagner, Alejandro Wolf‐Yadlin, Mark Sevecka, Jennifer K. Grenier, David E. Root, Douglas A. Lauffenburger, Gavin MacBeath

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation mā Jason D. Arroyo, Alexis A. Jourdain, Sarah E. Calvo, Carmine Ballarano, John G. Doench, David E. Root, Vamsi K. Mootha

Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression mā Joseph Rosenbluh, Han Xu, William F. Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn

Chronos: a CRISPR cell population dynamics model mā Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects mā Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland

Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects mā Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark‐Anthony Bray, Federica Piccioni, David E. Root, John G. Doench, Jesse S. Boehm, Anne E. Carpenter

A Genome-Scale RNA Interference Screen Implicates NF1 Loss in Resistance to RAF Inhibition mā Steven R. Whittaker, Jean‐Philippe Theurillat, Eliezer M. Van Allen, Nikhil Wagle, Jessica Hsiao, Glenn S. Cowley, Dirk Schadendorf, David E. Root, Levi A. Garraway

High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons mā Thomas J.F. Nieland, David J. Logan, Jessica L. Saulnier, Daniel D. Lam, Caroline A. Johnson, David E. Root, Anne E. Carpenter, Bernardo L. Sabatini

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells mā Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David Scott, Tarjei S. Mikkelsen, Dirk Heckl, Benjamin L. Ebert, David E. Root, John G. Doench, Feng Zhang

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways mā Michelle Dang, Nicole Armbruster, Miles A. Miller, Efraín A. Cermeño, Monika Hartmann, George W. Bell, David E. Root, Douglas A. Lauffenburger, Harvey F. Lodish, Andreas Herrlich

CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines mā Daniel J. Merk, Linda Paul, Foteini Tsiami, Helen Hohenthanner, Ghazal Mohseni Kouchesfahani, Lara A. Haeusser, Bianca Walter, Adam Brown, Nicole S. Persky, David E. Root, Ghazaleh Tabatabai

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen mā Benjamin L. Ebert, Jennifer Pretz, Jocelyn Bosco, Cindy Chang, Pablo Tamayo, Naomi Galili, Azra Raza, David E. Root, Eyal C. Attar, Steven R. Ellis, Todd R. Golub

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