نتائج البحث - David E. Root
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Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool حسب Katherine Donovan, Mudra Hegde, Meagan E. Sullender, Emma W Vaimberg, Cory M. Johannessen, David E. Root, John G. Doench
منشور في 2017Artigo -
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Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression حسب Joseph Rosenbluh, Han Xu, William F. Harrington, Stanley Gill, Xiaoxing Wang, Francisca Vázquez, David E. Root, Aviad Tsherniak, William C. Hahn
منشور في 2017Artigo -
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Chronos: a CRISPR cell population dynamics model حسب Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland
منشور في 2021Pré-impressão -
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Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects حسب Joshua M. Dempster, Isabella Boyle, Francisca Vázquez, David E. Root, Jesse S. Boehm, William C. Hahn, Aviad Tsherniak, James M. McFarland
منشور في 2021Artigo -
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Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects حسب Shantanu Singh, Xiaoyun Wu, Vebjorn Ljosa, Mark‐Anthony Bray, Federica Piccioni, David E. Root, John G. Doench, Jesse S. Boehm, Anne E. Carpenter
منشور في 2015Artigo -
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A Genome-Scale RNA Interference Screen Implicates NF1 Loss in Resistance to RAF Inhibition حسب Steven R. Whittaker, Jean‐Philippe Theurillat, Eliezer M. Van Allen, Nikhil Wagle, Jessica Hsiao, Glenn S. Cowley, Dirk Schadendorf, David E. Root, Levi A. Garraway
منشور في 2013Artigo -
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High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons حسب Thomas J.F. Nieland, David J. Logan, Jessica L. Saulnier, Daniel D. Lam, Caroline A. Johnson, David E. Root, Anne E. Carpenter, Bernardo L. Sabatini
منشور في 2014Artigo -
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Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways حسب Michelle Dang, Nicole Armbruster, Miles A. Miller, Efraín A. Cermeño, Monika Hartmann, George W. Bell, David E. Root, Douglas A. Lauffenburger, Harvey F. Lodish, Andreas Herrlich
منشور في 2013Artigo -
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CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines حسب Daniel J. Merk, Linda Paul, Foteini Tsiami, Helen Hohenthanner, Ghazal Mohseni Kouchesfahani, Lara A. Haeusser, Bianca Walter, Adam Brown, Nicole S. Persky, David E. Root, Ghazaleh Tabatabai
منشور في 2024Artigo -
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An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription حسب Matthieu Giraud, Nada Jmari, Lina Du, Floriane Carallis, Thomas J.F. Nieland, Flor M. Pérez-Campo, Olivier Bensaude, David E. Root, Nir Hacohen, Diane Mathis, Christophe Benoist
منشور في 2014Artigo -
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أدوات البحث:
موضوعات ذات صلة
Biology
Genetics
Gene
Cancer research
Computational biology
Cell biology
Cancer
Medicine
CRISPR
Genome
RNA
Gene expression
Signal transduction
Biochemistry
Mutation
Cell cycle
Computer science
Phenotype
Transcription factor
Gene knockdown
RNA interference
Cancer cell
Internal medicine
Kinase
Artificial intelligence
Carcinogenesis
Cas9
Immunology
KRAS
Chemistry