Výsledky vyhledávání - Danan Li

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  1. 1
    A dual role for the immune response in a mouse model of inflammation-associated lung cancer

    A dual role for the immune response in a mouse model of inflammation-associated lung cancer Autor Michael Dougan, Danan Li, Donna Neuberg, Martín C. Mihm, Paul B. Googe, Kwok‐Kin Wong, Glenn Dranoff

    Vydáno 2011
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  2. 2
    A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

    A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene Autor Ji Luo, Michael J. Emanuele, Danan Li, Chad J. Creighton, Michael R. Schlabach, Thomas F. Westbrook, Kwok‐Kin Wong, Stephen J. Elledge

    Vydáno 2009
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  3. 3
    Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

    Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells Autor Stephen J. Curtis, Kerstin W. Sinkevicius, Danan Li, Allison N. Lau, Rebecca R. Roach, Raffaella Zamponi, Amber Woolfenden, David G. Kirsch, Kwok‐Kin Wong, Carla F. Kim

    Vydáno 2010
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  4. 4
    PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor

    PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor Autor Kai Wang, Qin Zhang, Danan Li, Keith A. Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang, Paul A. Rejto, James G. Christensen, Peter Olson

    Vydáno 2015
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  5. 5
    Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

    Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition Autor Anthony C. Faber, Danan Li, Young-Chul Song, Mei‐Chih Liang, Beow Y. Yeap, Roderick T. Bronson, Eugene Lifshits, Chen Zhao, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Kwok‐Kin Wong, Jeffrey A. Engelman

    Vydáno 2009
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  6. 6
    β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations

    β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations Autor Sohei Nakayama, Natasha Sng, Julián Carretero, Robert S. Welner, Yuichiro Hayashi, Mihoko Yamamoto, Alistair J. Tan, Norihiro Yamaguchi, Hiroyuki Yasuda, Danan Li, Kenzo Soejima, Ross A. Soo, Daniel B. Costa, Kwok‐Kin Wong, Susumu Kobayashi

    Vydáno 2014
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  7. 7
    An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

    An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation Autor Birgit Schoeberl, Anthony C. Faber, Danan Li, Mei‐Chih Liang, Katherine Crosby, Matthew Onsum, Olga Burenkova, Emily Pace, Zandra E. Walton, Lin Nie, Aaron Fulgham, Youngchul Song, Ulrik B. Nielsen, Jeffrey A. Engelman, Kwok‐Kin Wong

    Vydáno 2010
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  8. 8
    Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

    Novel mutant-selective EGFR kinase inhibitors against EGFR T790M Autor Wenjun Zhou, Dalia Ercan, Liang Chen, Cai‐Hong Yun, Danan Li, Marzia Capelletti, Alexis B. Cortot, Lucian R. Chirieac, Roxana E. Iacob, Robert F. Padera, John R. Engen, Kwok‐Kin Wong, Michael J. Eck, Nathanael S. Gray, Pasi A. Jänne

    Vydáno 2009
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  9. 9
    Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

    Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition Autor Neil Johnson, Yuchen Li, Zandra E. Walton, Katherine A. Cheng, Danan Li, Scott J. Rodig, Lisa A. Moreau, Christine Unitt, Roderick T. Bronson, Huw D. Thomas, David R. Newell, Alan D. D’Andrea, Nicola J. Curtin, Kwok‐Kin Wong, Geoffrey I. Shapiro

    Vydáno 2011
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  10. 10
    Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

    Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors Autor Thomas De Raedt, Zandra E. Walton, Jessica L. Yecies, Danan Li, Yimei Chen, Clare F. Malone, Ophélia Maertens, Seung Min Jeong, Roderick T. Bronson, Valerie S. LeBleu, Raghu Kalluri, Emmanuel Normant, Marcia C. Haigis, Brendan D. Manning, Kwok‐Kin Wong, Kay F. Macleod, Karen Cichowski

    Vydáno 2011
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  11. 11
    Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin

    Regression of Drug-Resistant Lung Cancer by the Combination of Rosiglitazone and Carboplatin Autor Geoffrey D. Girnun, Liang Chen, Jessica M. Silvaggi, Ronny Drapkin, Lucian R. Chirieac, Robert F. Padera, Rabi Upadhyay, Scott B. Vafai, Ralph Weissleder, Umar Mahmood, Elnaz Naseri, Stephanie Buckley, Danan Li, Jeremy Force, Kate McNamara, George D. Demetri, Bruce M. Spiegelman, Kwok‐Kin Wong

    Vydáno 2008
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  12. 12
    Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer

    Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer Autor Takeshi Shimamura, Samanthi A. Perera, Kevin P. Foley, Jim Sang, Scott J. Rodig, Takayo Inoue, Liang Chen, Danan Li, Julián Carretero, Yuchen Li, Papiya Sinha, Christopher D. Carey, Christa L. Borgman, John-Paul Jimenez, Matthew Meyerson, Weiwen Ying, James Barsoum, Kwok‐Kin Wong, Geoffrey I. Shapiro

    Vydáno 2012
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  13. 13
    Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models

    Mutations in BRAF and KRAS Converge on Activation of the Mitogen-Activated Protein Kinase Pathway in Lung Cancer Mouse Models Autor Hongbin Ji, Zhenxiong Wang, Samanthi A. Perera, Danan Li, Mei‐Chih Liang, Sara Zaghlul, Kate McNamara, Liang Chen, Mitchell Albert, Yanping Sun, Ruqayyah Al-Hashem, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, Roman K. Thomas, Levi A. Garraway, Pasi A. Jänne, Bruce E. Johnson, Lynda Chin, Kwok‐Kin Wong

    Vydáno 2007
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  14. 14
    HER2 <sup>YVMA</sup> drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

    HER2 <sup>YVMA</sup> drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy Autor Samanthi A. Perera, Danan Li, Takeshi Shimamura, Maria Gabriela Raso, Hongbin Ji, Liang Chen, Christa L. Borgman, Sara Zaghlul, K. Brandstetter, Shigeto Kubo, Masaya Takahashi, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, Geoffrey I. Shapiro, Heidi Greulich, Matthew Meyerson, Ulrich Guertler, Pilar Garin Chesa, Flavio Solca, Ignacio I. Wistuba, Kwok‐Kin Wong

    Vydáno 2009
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  15. 15
    The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

    The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies Autor Hongbin Ji, Danan Li, Liang Chen, Takeshi Shimamura, Susumu Kobayashi, Kate McNamara, Umar Mahmood, Mitchell Albert, Yangping Sun, Ruqayyah Al-Hashem, Lucian R. Chirieac, Robert F. Padera, Roderick T. Bronson, William Kim, Pasi A. Jänne, Geoffrey I. Shapiro, Daniel G. Tenen, Bruce E. Johnson, Ralph Weissleder, Norman E. Sharpless, Kwok‐Kin Wong

    Vydáno 2006
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  16. 16
    Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance

    Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance Autor Takeshi Shimamura, Danan Li, Hongbin Ji, Henry J. Haringsma, Elizabeth Liniker, Christa L. Borgman, April M. Lowell, Yuko Minami, Kate McNamara, Samanthi A. Perera, Sara Zaghlul, Roman K. Thomas, Heidi Greulich, Susumu Kobayashi, Lucian R. Chirieac, Robert F. Padera, Shigeto Kubo, Masaya Takahashi, Daniel G. Tenen, Matthew Meyerson, Kwok‐Kin Wong, Geoffrey I. Shapiro

    Vydáno 2008
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  17. 17
    Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by <i>EML4-ALK</i> Fusion Oncogene

    Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by <i>EML4-ALK</i> Fusion Oncogene Autor Zhao Chen, Takaaki Sasaki, Xiaohong Tan, Julián Carretero, Takeshi Shimamura, Danan Li, Chunxiao Xu, Yuchuan Wang, Guillaume Adelmant, Marzia Capelletti, Hyun Joo Lee, Scott J. Rodig, Christa L. Borgman, Seung-Il Park, Hyeong Ryul Kim, Robert F. Padera, Jarrod A. Marto, Nathanael S. Gray, Andrew L. Kung, Geoffrey I. Shapiro, Pasi A. Jänne, Kwok‐Kin Wong

    Vydáno 2010
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  18. 18
    Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy

    Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy Autor Danan Li, Takeshi Shimamura, Hongbin Ji, Liang Chen, Henry J. Haringsma, Kate McNamara, Mei‐Chih Liang, Samanthi A. Perera, Sara Zaghlul, Christa L. Borgman, Shigeto Kubo, Masaya Takahashi, Yanping Sun, Lucian R. Chirieac, Robert F. Padera, Neal I. Lindeman, Pasi A. Jänne, Roman K. Thomas, Matthew Meyerson, Michael J. Eck, Jeffrey A. Engelman, Geoffrey I. Shapiro, Kwok‐Kin Wong

    Vydáno 2007
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  19. 19
    Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

    Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors Autor Hongbin Ji, Xiao‐Jun Zhao, Yuki Yuza, Takeshi Shimamura, Danan Li, Alexei Protopopov, Boonim L. Jung, Kate McNamara, Huili Xia, Karen A. Glatt, Roman K. Thomas, Hidefumi Sasaki, James W. Horner, Michael J. Eck, Mitchell Albert, Yangping Sun, Ruqayyah Al-Hashem, Roderick T. Bronson, Sridhar K. Rabindran, Carolyn Discafani, Elizabeth A. Maher, Geoffrey I. Shapiro, Matthew Meyerson, Kwok‐Kin Wong

    Vydáno 2006
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  20. 20
    Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

    Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions Autor Martin L. Sos, Kathrin Michel, Thomas Zander, Jonathan M. Weiss, Peter Frommolt, Martin Peifer, Danan Li, Roland T. Ullrich, Mirjam Koker, Florian Fischer, Takeshi Shimamura, Daniel Rauh, Craig H. Mermel, Stefanie Fischer, Isabel Stückrath, Stefanie Heynck, Rameen Beroukhim, William M. Lin, Wendy Winckler, Kinjal Shah, Thomas LaFramboise, Whei F. Moriarty, Megan Hanna, Laura Toloşi, Jörg Rahnenführer, Roel G.W. Verhaak, Derek Y. Chiang, Gad Getz, Martin Hellmich, Jürgen Wolf, Luc Girard, Michael Peyton, Barbara A. Weir, Tzu-Hsiu Chen, Heidi Greulich, Jordi Barretina, Geoffrey I. Shapiro, Levi A. Garraway, Adi F. Gazdar, John D. Minna, Matthew Meyerson, Kwok‐Kin Wong, Roman K. Thomas

    Vydáno 2009
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