Resultats de la cerca - Daichi Inoue

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  1. 1
    Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis

    Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis per Daichi Inoue, Robert K. Bradley, Omar Abdel‐Wahab

    Publicat 2016
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  2. 2
    Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels

    Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels per Daichi Inoue, Masaki Matsumoto, Reina Nagase, Makoto Saika, Takeshi Fujino, Keiichi I. Nakayama, Toshio Kitamura

    Publicat 2015
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  3. 3
    IP-10/CXCL10 and MIG/CXCL9 as novel markers for the diagnosis of lymphoma-associated hemophagocytic syndrome

    IP-10/CXCL10 and MIG/CXCL9 as novel markers for the diagnosis of lymphoma-associated hemophagocytic syndrome per Hayato Maruoka, Daichi Inoue, Yoko Takiuchi, Seiji Nagano, Hiroshi Arima, Sumie Tabata, Akiko Matsushita, Takayuki Ishikawa, T Oita, Takayuki Takahashi

    Publicat 2013
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  4. 4
    Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia

    Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia per Moe Kadono, Akinori Kanai, Akiko Nagamachi, Satoru Shinriki, Jin Kawata, Koji Iwato, Taiichi Kyo, Kumi Oshima, Akihiko Yokoyama, Takeshi Kawamura, Reina Nagase, Daichi Inoue, Toshio Kitamura, Toshiya Inaba, Tatsuo Ichinohe, Hirotaka Matsui

    Publicat 2016
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  5. 5
    SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS

    SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS per Daichi Inoue, Jiro Kitaura, Hirotaka Matsui, Hsin‐An Hou, Wen‐Chien Chou, Akiko Nagamachi, Kimihito C. Kawabata, Katsuhiro Togami, Reina Nagase, Saburo Horikawa, Makoto Saika, J-B Micol, Yasutaka Hayashi, Yuka Harada, Hironori Harada, Toshiya Inaba, Hwei‐Fang Tien, Omar Abdel‐Wahab, Toshio Kitamura

    Publicat 2014
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  6. 6
    Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation

    Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation per Reina Nagase, Daichi Inoue, Alessandro Pastore, Takeshi Fujino, Hsin‐An Hou, Norimasa Yamasaki, Susumu Goyama, Makoto Saika, Akinori Kanai, Yasuyuki Sera, Sayuri Horikawa, Yasunori Ota, Shuhei Asada, Yasutaka Hayashi, Kimihito C. Kawabata, Reina Takeda, Hwei‐Fang Tien, Hiroaki Honda, Omar Abdel‐Wahab, Toshio Kitamura

    Publicat 2018
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  7. 7
    Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis

    Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis per Shuhei Asada, Susumu Goyama, Daichi Inoue, Shiori Shikata, Reina Takeda, Tsuyoshi Fukushima, Taishi Yonezawa, Takeshi Fujino, Yasutaka Hayashi, Kimihito C. Kawabata, Tomofusa Fukuyama, Yosuke Tanaka, Akihiko Yokoyama, Satoshi Yamazaki, Hiroko Kozuka‐Hata, Masaaki Oyama, Shinya Kojima, Masahito Kawazu, Hiroyuki Mano, Toshio Kitamura

    Publicat 2018
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  8. 8
    ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia

    ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia per Jean-Baptiste Micol, Alessandro Pastore, Daichi Inoue, Nicolas Duployez, Eun Hee Kim, Stanley Chun-Wei Lee, Benjamin H. Durham, Young Rock Chung, Hana Cho, Xiao Jing Zhang, Akihide Yoshimi, Andrei V. Krivtsov, Richard P. Koche, Éric Solary, Amit Sinha, Claude Preudhomme, Omar Abdel‐Wahab

    Publicat 2017
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  9. 9
    Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

    Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia per Eric Wang, Sydney X. Lu, Alessandro Pastore, Xufeng Chen, Jochen Imig, Stanley Chun-Wei Lee, Kathryn Hockemeyer, Yohana Ghebrechristos, Akihide Yoshimi, Daichi Inoue, Michelle Ki, Hana Cho, Lillian Bitner, Andreas Kloetgen, Kuan‐Ting Lin, Taisuke Uehara, Takashi Owa, Raoul Tibes, Adrian R. Krainer, Omar Abdel‐Wahab, Iannis Aifantis

    Publicat 2019
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  10. 10
    Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations

    Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations per Daichi Inoue, Jiro Kitaura, Katsuhiro Togami, Koutarou Nishimura, Yutaka Enomoto, Tomoyuki Uchida, Yuki Kagiyama, Kimihito C. Kawabata, Fumio Nakahara, Kumi Izawa, Toshihiko Oki, Akie Maehara, Masamichi Isobe, Akiho Tsuchiya, Yuka Harada, Hironori Harada, Takahiro Ochiya, Hiroyuki Aburatani, Hiroshi Kimurâ, Felicitas Thol, Michael Heuser, Ross L. Levine, Omar Abdel‐Wahab, Toshio Kitamura

    Publicat 2013
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  11. 11
    Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway

    Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway per Takeshi Fujino, Susumu Goyama, Yuki Sugiura, Daichi Inoue, Shuhei Asada, Satoshi Yamasaki, Akiko Matsumoto, Kiyoshi Yamaguchi, Yumiko Isobe, Akiho Tsuchiya, Shiori Shikata, Naru Sato, Hironobu Morinaga, Tomofusa Fukuyama, Yosuke Tanaka, Tsuyoshi Fukushima, Reina Takeda, Keita Yamamoto, Hiroaki Honda, Emi K. Nishimura, Yoichi Furukawa, Tatsuhiro Shibata, Omar Abdel‐Wahab, Makoto Suematsu, Toshio Kitamura

    Publicat 2021
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  12. 12
    Spliceosomal disruption of the non-canonical BAF complex in cancer

    Spliceosomal disruption of the non-canonical BAF complex in cancer per Daichi Inoue, Guo-Liang Chew, Bo Liu, Brittany C. Michel, Joseph Pangallo, Andrew R. D’Avino, Tyler D. Hitchman, Khrystyna North, Stanley Chun-Wei Lee, Lillian Bitner, Ariele Block, Amanda R. Moore, Akihide Yoshimi, Luisa F. Escobar‐Hoyos, Hana Cho, Alex Penson, Sydney X. Lu, Justin Taylor, Yu Chen, Cigall Kadoch, Omar Abdel‐Wahab, Robert K. Bradley

    Publicat 2019
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  13. 13
    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis per Justin Taylor, Maria Sendino, Alexander N. Gorelick, Alessandro Pastore, Matthew T. Chang, Alexander Penson, Elena I. Gavrila, Connor Stewart, Ella M. Melnik, Florisela Herrejon Chavez, Lillian Bitner, Akihide Yoshimi, Stanley Chun-Wei Lee, Daichi Inoue, Bo Liu, Xiao J. Zhang, Anthony R. Mato, Ahmet Doǧan, Michael G. Kharas, Yuhong Chen, Demin Wang, Rajesh K. Soni, Ronald C. Hendrickson, Gorka Prieto, José Antonio Rodríguez, Barry S. Taylor, Omar Abdel‐Wahab

    Publicat 2019
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  14. 14
    Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

    Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition per Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J. Hogg, Yasutaka Hayashi, Jose Mario Bello Pineda, Ettaib El Marabti, Caroline Erickson, Katherine Knorr, Miki Fukumoto, Hiromi Yamazaki, Atsushi Tanaka, Chie Fukui, Sydney X. Lu, Benjamin H. Durham, Bo Liu, Eric Wang, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, Alex Penson, Guo-Liang Chew, Frank McCormick, Robert K. Bradley, Omar Abdel‐Wahab

    Publicat 2021
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  15. 15
    BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

    BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state per Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang, Yifan Zhang, Tomohiro Akashi, Aaron D. Viny, Tsukasa Shigehiro, Tomokatsu Ikawa, Hiromi Yamazaki, Miki Fukumoto, Atsushi Tanaka, Yasutaka Hayashi, Yui Koike, Yumi Aoyama, Hiromi Ito, Hiroyoshi Nishikawa, Toshio Kitamura, Akinori Kanai, Akihiko Yokoyama, Tohru Fujiwara, Susumu Goyama, Hideki Noguchi, Stanley Chun-Wei Lee, Atsushi Toyoda, Kunihiko Hinohara, Omar Abdel‐Wahab, Daichi Inoue

    Publicat 2023
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  16. 16
    Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies

    Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies per Justin Taylor, Dean C. Pavlick, Akihide Yoshimi, Christina Marcelus, Stephen S. Chung, Jaclyn F. Hechtman, Ryma Benayed, Emiliano Cocco, Benjamin H. Durham, Lillian Bitner, Daichi Inoue, Young Rock Chung, Kerry Mullaney, Justin M. Watts, Eli L. Diamond, Lee A. Albacker, Tariq I. Mughal, Kevin Ebata, Brian B. Tuch, Nora Ku, Maurizio Scaltriti, Mikhail Roshal, Maria E. Arcila, Siraj M. Ali, David M. Hyman, Jae H. Park, Omar Abdel‐Wahab

    Publicat 2018
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  17. 17
    Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

    Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations per Stanley Chun-Wei Lee, Khrystyna North, Eun Hee Kim, Eunjung Jang, Esther A. Obeng, Sydney X. Lu, Bo Liu, Daichi Inoue, Akihide Yoshimi, Michelle Ki, Mirae Yeo, Xiao Jing Zhang, Min Kyung Kim, Hana Cho, Young Rock Chung, Justin Taylor, Benjamin H. Durham, Young Joon Kim, Alessandro Pastore, Sébastien Monette, James Palacino, Michael Seiler, Silvia Buonamici, Peter G. Smith, Benjamin L. Ebert, Robert K. Bradley, Omar Abdel‐Wahab

    Publicat 2018
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  18. 18
    ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine

    ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine per Nora E. Rahmani, Nandini Ramachandra, Srabani Sahu, Nadege Gitego, Andrea López, Kith Pradhan, Tushar D. Bhagat, Shanisha Gordon-Mitchell, Bianca Rivera-Peña, Mohammad Hossein Kazemi, K. Visweswara Rao, Orsi Giricz, Shahina B. Maqbool, Raul Olea, Yongmei Zhao, Jinghang Zhang, Hamid Dolatshad, Vickram Tittrea, Dharamveer Tatwavedi, Shalini Singh, Juseong Lee, Tianyu Sun, Ulrich Steidl, Aditi Shastri, Daichi Inoue, Omar Abdel‐Wahab, Andrea Pellagatti, Evripidis Gavathiotis, Jacqueline Boultwood, Amit Verma

    Publicat 2021
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  19. 19
    Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis

    Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis per Akihide Yoshimi, Kuan‐Ting Lin, Daniel H. Wiseman, Mohammad Alinoor Rahman, Alessandro Pastore, Bo Wang, Stanley Chun-Wei Lee, Jean‐Baptiste Micol, Xiao Jing Zhang, Stéphane de Botton, Virginie Penard‐Lacronique, Eytan M. Stein, Hana Cho, Rachel E. Miles, Daichi Inoue, Todd R. Albrecht, Tim C. P. Somervaille, Kiran Batta, Fabio M. R. Amaral, Fabrizio Simeoni, Deepti P. Wilks, Catherine Cargo, Andrew M. Intlekofer, Ross L. Levine, Heidi Dvinge, Robert K. Bradley, Eric J. Wagner, Adrian R. Krainer, Omar Abdel‐Wahab

    Publicat 2019
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