نتائج البحث - Cory M. Johannessen
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Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool حسب Katherine Donovan, Mudra Hegde, Meagan E. Sullender, Emma W Vaimberg, Cory M. Johannessen, David E. Root, John G. Doench
منشور في 2017Artigo -
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REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species حسب Leif W. Ellisen, Kate D Ramsayer, Cory M. Johannessen, Annie Yang, Hideyuki Beppu, Karolina Minda, Jonathan D. Oliner, Frank McKeon, Daniel A. Haber
منشور في 2002Artigo -
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A negative feedback signaling network underlies oncogene-induced senescence حسب Stéphanie Courtois-Cox, Sybil M. Genther Williams, Elizabeth E. Reczek, Bryan W. Johnson, Lauren T. McGillicuddy, Cory M. Johannessen, Pablo E. Hollstein, Mia MacCollin, Karen Cichowski
منشور في 2006Artigo -
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A melanocyte lineage program confers resistance to MAP kinase pathway inhibition حسب Cory M. Johannessen, Laura A. Johnson, Federica Piccioni, Aisha Townes, Dennie T. Frederick, Melanie Donahue, Rajiv Narayan, Keith T. Flaherty, Jennifer A. Wargo, David E. Root, Levi A. Garraway
منشور في 2013Artigo -
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A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma حسب Tikvah K. Hayes, Flora Luo, Ofir Cohen, Amy Goodale, Yenarae Lee, Sasha Pantel, Mukta Bagul, Federica Piccioni, David E. Root, Levi A. Garraway, Matthew Meyerson, Cory M. Johannessen
منشور في 2019Artigo -
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TORC1 Is Essential for NF1-Associated Malignancies حسب Cory M. Johannessen, Bryan W. Johnson, Sybil M. Genther Williams, Annie W. Chan, Elizabeth E. Reczek, Ryan C. Lynch, Matthew J. Rioth, Andrea I. McClatchey, Sandra Ryeom, Karen Cichowski
منشور في 2008Artigo -
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Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling حسب Nikhil Wagle, W. Marston Linehan, Michael F. Berger, Matthew J. Davis, Allison M. Sawyer, Panisa Pochanard, Sarah M. Kehoe, Cory M. Johannessen, Laura E. MacConaill, William C. Hahn, Matthew Meyerson, Levi A. Garraway
منشور في 2011Artigo -
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Phenotypic Characterization of a Comprehensive Set of MAPK1 /ERK2 Missense Mutants حسب Lisa Brenan, Aleksandr Andreev, Ofir Cohen, Sasha Pantel, Atanas Kamburov, Davide Cacchiarelli, Nicole S. Persky, Cong Zhu, Mukta Bagul, Eva M. Goetz, Alex B. Burgin, Levi A. Garraway, Gad Getz, Tarjei S. Mikkelsen, Federica Piccioni, David E. Root, Cory M. Johannessen
منشور في 2016Artigo -
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DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance حسب Katsuhiro Togami, Timothy J. Pastika, Jason Stephansky, Mahmoud Ghandi, Amanda L. Christie, Kristen L. Jones, C. Anderson Johnson, Ross Lindsay, Christopher Brooks, Anthony Letai, Jeffrey W. Craig, Olga Pozdnyakova, David M. Weinstock, Joan Montero, Jon C. Aster, Cory M. Johannessen, Andrew A. Lane
منشور في 2019Artigo -
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A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors حسب David J. Konieczkowski, Cory M. Johannessen, Omar O. Abudayyeh, Jong Wook Kim, Zachary A. Cooper, Adriano Piris, Dennie T. Frederick, Michal Barzily-Rokni, Ravid Straussman, Rizwan Haq, David E. Fisher, Jill P. Mesirov, William C. Hahn, Keith T. Flaherty, Jennifer A. Wargo, Pablo Tamayo, Levi A. Garraway
منشور في 2014Artigo -
15
A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer حسب Frederick H. Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, Mohit Butaney, Tanaz Sharifnia, Stacey B. Gabriel, Jill P. Mesirov, William C. Hahn, Jeffrey A. Engelman, Matthew Meyerson, David E. Root, Pasi A. Jänne, Levi A. Garraway
منشور في 2015Artigo -
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A public genome-scale lentiviral expression library of human ORFs حسب Xiaoping Yang, Jesse S. Boehm, Xinping Yang, Kourosh Salehi‐Ashtiani, Tong Hao, Yun Shen, Rakela Lubonja, Sapana Thomas, Ozan Alkan, Tashfeen Bhimdi, Thomas Green, Cory M. Johannessen, Serena J. Silver, Cindy M. Nguyen, Ryan R. Murray, Haley Hieronymus, Dawit Balcha, Changyu Fan, Chenwei Lin, Lila Ghamsari, Marc Vidal, William C. Hahn, David E. Hill, David E. Root
منشور في 2011Artigo -
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Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling حسب Amanda Balboni Iniguez, Gabriela Alexe, Emily Jue Wang, Giovanni Roti, Sarvagna Patel, Liying Chen, Samuel Kitara, Amy Saur Conway, Amanda L. Robichaud, Björn Stolte, Pratiti Bandopadhayay, Amy Goodale, Sasha Pantel, Yenarae Lee, Dorian M. Cheff, Matthew D. Hall, Rajarshi Guha, Mindy I. Davis, Marie Ménard, Nicole Nasholm, William A. Weiss, Jun Qi, Rameen Beroukhim, Federica Piccioni, Cory M. Johannessen, Kimberly Stegmaier
منشور في 2018Artigo -
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Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants حسب Tikvah K. Hayes, Elisa Aquilanti, Nicole S. Persky, Xiaoping Yang, Erica Kim, Lisa Brenan, Amy Goodale, Douglas Alan, Ted Sharpe, Robert Shue, Lindsay Westlake, Lior Golomb, Brianna Silverman, Myshal D. Morris, Ty Running Fisher, Eden Beyene, Yvonne Li, Andrew D. Cherniack, Federica Piccioni, J. Kevin Hicks, Andrew Chi, Daniel P. Cahill, Jörg Dietrich, Tracy T. Batchelor, David E. Root, Cory M. Johannessen, Matthew Meyerson
منشور في 2024Artigo -
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MAP Kinase Pathway Alterations in <i>BRAF</i>-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition حسب Nikhil Wagle, Eliezer M. Van Allen, Daniel J. Treacy, Dennie T. Frederick, Zachary A. Cooper, Amaro Taylor‐Weiner, Mara Rosenberg, Eva M. Goetz, Ryan J. Sullivan, Deborah Farlow, Dennis C. Friedrich, Kristin Anderka, Danielle Perrin, Cory M. Johannessen, Aaron McKenna, Kristian Cibulskis, Gregory V. Kryukov, Eran Hodis, Donald P. Lawrence, Sheila Fisher, Gad Getz, Stacey Gabriel, Scott L. Carter, Keith T. Flaherty, Jennifer A. Wargo, Levi A. Garraway
منشور في 2013Artigo -
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Mutational processes shape the landscape of TP53 mutations in human cancer حسب Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner, James M. McFarland, Marc Duby, Jaegil Kim, Thomas P. Howard, David Y. Takeda, Seav Huong Ly, Eejung Kim, Hugh Gannon, Brian Hurhula, Ted Sharpe, Amy Goodale, Briana Fritchman, Scott Steelman, Francisca Vázquez, Aviad Tsherniak, Andrew J. Aguirre, John G. Doench, Federica Piccioni, Charles W.M. Roberts, Matthew Meyerson, Gad Getz, Cory M. Johannessen, David E. Root, William C. Hahn
منشور في 2018Artigo
أدوات البحث:
موضوعات ذات صلة
Biology
Genetics
Gene
Cancer research
Cell biology
Computational biology
Mutation
Melanoma
Cancer
Kinase
Medicine
Mutant
Signal transduction
Cell
Gene expression
MAPK/ERK pathway
Transcription factor
Cell cycle
Effector
Genome
PI3K/AKT/mTOR pathway
Phenotype
Apoptosis
Biochemistry
DNA
Downregulation and upregulation
Function (biology)
KRAS
MEK inhibitor
Trametinib