檢索結果 - Colin D. Weekes
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Phase I Study of Rigosertib, an Inhibitor of the Phosphatidylinositol 3-Kinase and Polo-like Kinase 1 Pathways, Combined with Gemcitabine in Patients with Solid Tumors and Pancreat... 由 Wen Wee, Wells A. Messersmith, Grace K. Dy, Colin D. Weekes, Amy Whitworth, Chen Ren, Manoj Maniar, François Wilhelm, Sabine Eckhardt, Alex A. Adjei, Antonio Jimeno
出版 2012Artigo -
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CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming 由 Agnieszka A. Kendrick, Johnathon Schafer, Monika Dzieciątkowska, Travis Nemkov, Angelo D’Alessandro, Deepika Neelakantan, Heide L. Ford, Chad G. Pearson, Colin D. Weekes, Kirk C. Hansen, Elan Eisenmesser
出版 2016Artigo -
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A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC-0994 in Patients with Advanced Solid Tumors 由 Colin D. Weekes, A. Craig Lockhart, Patricia LoRusso, Elaine Murray, Erica Park, Mike Tagen, Jatinder Singh, Indrani Sarkar, Lars Müeller, Hatem Dokainish, Geoffrey I. Shapiro, Howard A. Burris
出版 2020Artigo -
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Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma 由 Aaron J. Grossberg, Linda C. Chu, Christopher R. Deig, Eliot Fishman, William L. Hwang, Anirban Maitra, Daniel L. Marks, Arnav Mehta, Nima Nabavizadeh, Diane M. Simeone, Colin D. Weekes, Charles R. Thomas
出版 2020Revisão -
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Prognostic Factors of Survival in a Randomized Phase III Trial (MPACT) of Weekly <i>nab-</i>Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone in Patients With Metastatic Pancrea... 由 Josep Tabernero, E. Gabriela Chiorean, Jeffrey R. Infante, Sunil R. Hingorani, Vinod Ganju, Colin D. Weekes, Werner Scheithauer, Ramesh K. Ramanathan, David Goldstein, Darryl Penenberg, Alfredo Romano, Stefano Ferrara, Daniel D. Von Hoff
出版 2015Artigo -
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First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody–Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors 由 John H. Strickler, Colin D. Weekes, John Nemunaitis, Ramesh K. Ramanathan, Rebecca S. Heist, Daniel Morgensztern, Eric Angevin, Todd M. Bauer, Huibin Yue, Monica Motwani, Apurvasena Parikh, Edward B. Reilly, Daniel Afar, Louie Naumovski, Karen Kelly
出版 2018Artigo -
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Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer 由 Efrat Dotan, Dana B. Cardin, Heinz‐Josef Lenz, Wells A. Messersmith, Bert H. O’Neil, Steven J. Cohen, Crystal S. Denlinger, Safi Shahda, Igor Astsaturov, Ann M. Kapoun, Rainer K. Brachmann, Shailaja Uttamsingh, Robert Stagg, Colin D. Weekes
出版 2020Artigo -
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A Phase I Study of Dinaciclib in Combination With MK‐2206 in Patients With Advanced Pancreatic Cancer 由 Adrian Murphy, Marianna Zahurak, Mirat Shah, Colin D. Weekes, Aaron R. Hansen, Lillian L. Siu, Anna Spreafico, Noelle K. LoConte, Nicole M. Anders, T. Miles, Michelle A. Rudek, L. Austin Doyle, Barry D. Nelkin, Anirban Maitra, Nilofer S. Azad
出版 2020Artigo -
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The Incidence, Risk Factors, and Outcomes With 5-Fluorouracil–Associated Coronary Vasospasm 由 Amna Zafar, Zsófia D. Drobni, Ramya Mosarla, Raza M. Alvi, Matthew Lei, Uvette Lou, Vineet K. Raghu, Sean Murphy, Maeve Jones‐O’Connor, Sarah Hartmann, Hannah Gilman, Colin D. Weekes, John R. Clark, Jeffrey W. Clark, Lawrence S. Blaszkowsky, Erica Tavares, Tomas G. Neilan
出版 2021Artigo -
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A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor 由 Johanna C. Bendell, Milind Javle, Tanios Bekaii‐Saab, Richard S. Finn, Zev A. Wainberg, Daniel A. Laheru, Colin D. Weekes, Benjamin Tan, Gazala Khan, Mark M. Zalupski, Jeffrey R. Infante, Suzanne F. Jones, Kyriakos P. Papadopoulos, Anthony W. Tolcher, Renae Chavira, Janna Christy‐Bittel, Emma Barrett, Amita Patnaik
出版 2017Artigo -
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Phase I Study of Oral Rigosertib (ON 01910.Na), a Dual Inhibitor of the PI3K and Plk1 Pathways, in Adult Patients with Advanced Solid Malignancies 由 Daniel W. Bowles, Jennifer R. Diamond, Elaine T. Lam, Colin D. Weekes, David P. Astling, Ryan T. Anderson, Stephen Leong, Lia Gore, Marileila Varella‐Garcia, Brian W. Vogler, Stephen B. Keysar, Elizabeth Freas, Dara L. Aisner, Chen Ren, Aik Choon Tan, François Wilhelm, Manoj Maniar, Sabine Eckhardt, Wells A. Messersmith, Antonio Jimeno
出版 2014Artigo -
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Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial 由 Shubham Pant, Zev A. Wainberg, Colin D. Weekes, Muhammad Furqan, Pashtoon Murtaza Kasi, Craig Devoe, Alexis D. Leal, Vincent Chung, Olca Baştürk, Haley VanWyk, Amy Tavares, Lochana M. Seenappa, James Perry, Thian Kheoh, Lisa K. McNeil, Esther Welkowsky, Peter C. DeMuth, Christopher M. Haqq, Eileen M. O’Reilly
出版 2024Artigo -
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Multicenter Phase I Trial of the Mitogen-Activated Protein Kinase 1/2 Inhibitor BAY 86-9766 in Patients with Advanced Cancer 由 Colin D. Weekes, Daniel D. Von Hoff, Alex A. Adjei, Diane P. Leffingwell, Sabine Eckhardt, Lia Gore, Karl D. Lewis, Glen J. Weiss, Ramesh K. Ramanathan, Grace K. Dy, Wen Wang, Beth Sheedy, Cory Iverson, Jeffrey N. Miner, Zancong Shen, Li‐Tain Yeh, Ronald L. Dubowy, Michael Jeffers, Prabhu Rajagopalan, Neil J. Clendeninn
出版 2013Artigo -
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Tumor Microenvironment Immune Response in Pancreatic Ductal Adenocarcinoma Patients Treated With Neoadjuvant Therapy 由 Theodoros Michelakos, Lei Cai, Vincenzo Villani, Francesco Sabbatino, Filippos Kontos, Carlos Fernández-del Castillo, Teppei Yamada, Azfar Neyaz, Martin S. Taylor, Vikram Deshpande, Tomohiro Kurokawa, David T. Ting, Motaz Qadan, Colin D. Weekes, Jill N. Allen, Jeffrey W. Clark, Theodore S. Hong, David P. Ryan, Jennifer Y. Wo, Andrew L. Warshaw, Keith D. Lillemoe, Soldano Ferrone, Cristina R. Ferrone
出版 2020Artigo -
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Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcino... 由 Dung T. Le, Vincent J. Picozzi, Andrew H. Ko, Zev A. Wainberg, Hedy L. Kindler, Andrea Wang‐Gillam, Paul E. Oberstein, Michael A. Morse, Herbert J. Zeh, Colin D. Weekes, Tony Reid, Erkut Borazanci, Todd S. Crocenzi, Noelle K. LoConte, Benjamin Musher, Dan Laheru, Aimee Murphy, Chan C. Whiting, Nitya Nair, Amanda Enstrom, Sandy Ferber, Dirk G. Brockstedt, Elizabeth M. Jaffee
出版 2019Carta -
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Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer 由 Susan G. R. McDuff, Karin M. Hardiman, Peter Ulintz, Aparna R. Parikh, Hui Zheng, Daniel W. Kim, Jochen K. Lennerz, Mehlika Hazar-Rethinam, Emily E. Van Seventer, Isobel J. Fetter, Brandon Nadres, Christine E. Eyler, David P. Ryan, Colin D. Weekes, Jeffrey W. Clark, James C. Cusack, Lipika Goyal, Andrew X. Zhu, Jennifer Y. Wo, Lawrence S. Blaszkowsky, Jill N. Allen, Ryan B. Corcoran, Theodore S. Hong
出版 2021Artigo -
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Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies 由 Shadi A. Esfahani, Hua Ma, Shriya Krishna, Sergey Shuvaev, Mark F Sabbagh, Caitlin Deffler, Nicholas J. Rotile, Jonah Weigand‐Whittier, Iris Y. Zhou, Ciprian Catana, Onofrio A. Catalano, David T. Ting, Pedram Heidari, Eric Abston, Michael Lanuti, Genevieve M. Boland, Priyanka Pathak, Hannah Roberts, Kenneth K. Tanabe, Motaz Qadan, Carlos Fernàndez-del Castillo, Angela Shih, Aparna R. Parikh, Colin D. Weekes, Theodore S. Hong, Peter Caravan
出版 2024Artigo -
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Serial ctDNA Monitoring to Predict Response to Systemic Therapy in Metastatic Gastrointestinal Cancers 由 Aparna R. Parikh, Amikasra Mojtahed, Jaime L. Schneider, Katie Kanter, Emily E. Van Seventer, Isobel J. Fetter, Ashraf Thabet, Madeleine G. Fish, Bezaye Teshome, Kathryn Fosbenner, Brandon Nadres, Heather A. Shahzade, Jill N. Allen, Lawrence S. Blaszkowsky, David P. Ryan, Bruce J. Giantonio, Lipika Goyal, Ryan David Nipp, Eric Roeland, Colin D. Weekes, Jennifer Y. Wo, Andrew X. Zhu, Dora Dias‐Santagata, A. John Iafrate, Jochen K. Lennerz, Theodore S. Hong, Giulia Siravegna, Nora Horick, Jeffrey W. Clark, Ryan B. Corcoran
出版 2020Artigo
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Internal medicine
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Chemotherapy
Gemcitabine
Biochemistry
Breast cancer
Gene
Kinase
MAPK/ERK pathway
MEK inhibitor
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KRAS
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