Хайлтын үр дүнгүүд - Chloe E. Emerson
- 2-н 1 - 2 үр дүнгүүдийг харуулж байна
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1
mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors -н Clare F. Malone, Chloe E. Emerson, Rachel Ingraham, William Barbosa, Stephanie Guerra, Haejin Yoon, Lin Liu, Franziska Michor, Marcia C. Haigis, Kay F. Macleod, Ophélia Maertens, Karen Cichowski
Хэвлэсэн 2017Artigo -
2
MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in <i>BRAF-, NRAS</i>-, and <i>NF1</i>-Mutant Melanomas -н Ophélia Maertens, Ryan Kuzmickas, Haley E. Manchester, Chloe E. Emerson, Alessandra G. Gavin, Caroline J. Guild, Terence C. Wong, Thomas De Raedt, Christian Bowman-Colin, Elodie Hatchi, Levi A. Garraway, Keith T. Flaherty, Shailja Pathania, Stephen J. Elledge, Karen Cichowski
Хэвлэсэн 2019Artigo
Хайх хэрэгслүүд:
Холбогдох сэдвүүд
Biology
Cancer research
Genetics
KRAS
Signal transduction
Biochemistry
Cancer
Cell biology
Colorectal cancer
DNA
DNA damage
DNA repair
Gene
HDAC3
Histone
Histone deacetylase
MAPK/ERK pathway
MEK inhibitor
Melanoma
Mutant
Mutation
Neuroblastoma RAS viral oncogene homolog
Oxidative stress
PI3K/AKT/mTOR pathway
Synthetic lethality
TXNIP
Thioredoxin