Search Results - Chang‐Jiun Wu

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  1. 1
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer by Yang Chen, Jiha Kim, Sujuan Yang, Huamin Wang, Chang‐Jiun Wu, Hikaru Sugimoto, Valerie S. LeBleu, Raghu Kalluri

    Published 2021
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  2. 2
    Why is melanoma so metastatic?

    Why is melanoma so metastatic? by Russell R. Braeuer, Ian R. Watson, Chang‐Jiun Wu, Aaron K. Mobley, Takafumi Kamiya, Einav Shoshan, Menashe Bar‐Eli

    Published 2013
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  3. 3
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer by Yang Chen, Sujuan Yang, Jena Tavormina, Désirée Tampe, Michael Zeisberg, Huamin Wang, Krishnan K. Mahadevan, Chang‐Jiun Wu, Hikaru Sugimoto, Chia‐Chi Chang, Robert R. Jenq, Kathleen M. McAndrews, Raghu Kalluri

    Published 2022
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  4. 4
    Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in <i>APC</i>-Mutated Colorectal Cancer

    Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in <i>APC</i>-Mutated Colorectal Cancer by Rumi Lee, Jiexi Li, Jun Li, Chang‐Jiun Wu, Shan Jiang, Wen-Hao Hsu, Deepavali Chakravarti, Peiwen Chen, Kyle A. LaBella, Jing Li, Denise J. Spring, Di Zhao, Yanru Wang, Ronald A. DePinho

    Published 2022
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  5. 5
    USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation

    USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation by Pingping Hou, Xingdi Ma, Qiang Zhang, Chang‐Jiun Wu, Wenting Liao, Jun Li, Huamin Wang, Jun Zhao, Xin Zhou, Carolyn Guan, Jeffery Ackroyd, Shan Jiang, Jianhua Zhang, Denise J. Spring, Yanru Wang, Ronald A. DePinho

    Published 2019
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  6. 6
    Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer

    Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer by Pingping Hou, Avnish Kapoor, Qiang Zhang, Jiexi Li, Chang‐Jiun Wu, Jun Li, Zhengdao Lan, Ming Tang, Xingdi Ma, Jeffrey J. Ackroyd, Raghu Kalluri, Jianhua Zhang, Shan Jiang, Denise J. Spring, Yanru Wang, Ronald A. DePinho

    Published 2020
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  7. 7
    Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models

    Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models by Hong Seok Shim, James W. Horner, Chang‐Jiun Wu, Jiexi Li, Zheng D. Lan, Shan Jiang, Xueping Xu, Wen‐Hao Hsu, Tomasz Żal, Ivonne I. Flores, Pingna Deng, Yuan-Ta Lin, Li‐Huei Tsai, Yanru Wang, Ronald A. DePinho

    Published 2021
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  8. 8
    Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis

    Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis by Sara Lovisa, Eliot Fletcher-Sananikone, Hikaru Sugimoto, Janine Hensel, Sharmistha Lahiri, Alexandre Hertig, Gangadhar Taduri, Erica J. Lawson, Rajan Dewar, Ignacio Revuelta, Noritoshi Kato, Chang‐Jiun Wu, Roland L. Bassett, Nagireddy Putluri, Michael Zeisberg, Elisabeth M. Zeisberg, Valerie S. LeBleu, Raghu Kalluri

    Published 2020
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  9. 9
    Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression

    Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression by Wen‐Hao Hsu, Kyle A. LaBella, Yiyun Lin, Ping Xu, Rumi Lee, Cheng‐En Hsieh, Lei Yang, Ashley Zhou, Jonathan M. Blecher, Chang‐Jiun Wu, Kangyu Lin, Xiaoying Shang, Shan Jiang, Denise J. Spring, Yan Xia, Peiwen Chen, John Paul Shen, Scott Kopetz, Ronald A. DePinho

    Published 2023
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  10. 10
    Dual Roles of RNF2 in Melanoma Progression

    Dual Roles of RNF2 in Melanoma Progression by Kunal Rai, Kadir C. Akdemir, Lawrence N. Kwong, Petko Fiziev, Chang‐Jiun Wu, Emily Z. Keung, Sneha Sharma, Neha S. Samant, Maura Williams, Jacob B. Axelrad, Amiksha Shah, Dong Yang, Elizabeth A. Grimm, Michelle Barton, Denái R. Milton, Timothy P. Heffernan, James W. Horner, Sühendan Ekmekçioglu, Alexander J. Lazar, Jason Ernst, Lynda Chin

    Published 2015
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  11. 11
    Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases

    Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases by Zhihu Ding, Chang‐Jiun Wu, Mariela Jaskelioff, Elena Ivanova, Maria Kost‐Alimova, Alexei Protopopov, Gerald C. Chu, Guocan Wang, Xin Lü, Emma Labrot, Jian Hu, Wei Wang, Yonghong Xiao, Hailei Zhang, Jianhua Zhang, Jingfang Zhang, Boyi Gan, Samuel R. Perry, Shan Jiang, Li Li, James W. Horner, Yanru Wang, Lynda Chin, Ronald A. DePinho

    Published 2012
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  12. 12
    microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma

    microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma by Giannicola Genovese, Ayla Ergün, Sachet A. Shukla, Benito Campos, Jason A. Hanna, Papia Ghosh, Steven N. Quayle, Kunal Rai, Simona Colla, Haoqiang Ying, Chang‐Jiun Wu, Sharmistha Sarkar, Yonghong Xiao, Jianhua Zhang, Hailei Zhang, Lawrence N. Kwong, Katherine L. Dunn, Wolf R. Wiedemeyer, Cameron Brennan, Hongwu Zheng, David L. Rimm, James J. Collins, Lynda Chin

    Published 2012
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  13. 13
    Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

    Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes by Kenneth L. Scott, Cristina Nogueira, Timothy P. Heffernan, Remco van Doorn, Sabin Dhakal, Jason A. Hanna, Chengyin Min, Mariela Jaskelioff, Yonghong Xiao, Chang‐Jiun Wu, Lisa Cameron, Samuel R. Perry, Rhamy Zeid, Tamar Feinberg, Minjung Kim, George Vande Woude, Scott R. Granter, Marcus Bosenberg, Gerald C. Chu, Ronald A. DePinho, David L. Rimm, Lynda Chin

    Published 2011
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  14. 14
    Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer

    Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer by Di Zhao, Li Cai, Xin Lü, Xin Liang, Jiexi Li, Peiwen Chen, Michael Ittmann, Xiaoying Shang, Shan Jiang, Haoyan Li, Chenling Meng, Ivonne I. Flores, Jian H. Song, James W. Horner, Zhengdao Lan, Chang‐Jiun Wu, Jun Li, Qing Chang, Ko‐Chien Chen, Guocan Wang, Pingna Deng, Denise J. Spring, Yin Wang, Ronald A. DePinho

    Published 2020
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  15. 15
    Histone demethylase KDM5D upregulation drives sex differences in colon cancer

    Histone demethylase KDM5D upregulation drives sex differences in colon cancer by Jiexi Li, Zhengdao Lan, Wenting Liao, James W. Horner, Xueping Xu, Jielin Liu, Yohei Yoshihama, Shan Jiang, Hong Seok Shim, Max Slotnik, Kyle A. LaBella, Chang‐Jiun Wu, Kenneth Dunner, Wen-Hao Hsu, Rumi Lee, Isha Khanduri, Christopher Terranova, Kadir C. Akdemir, Deepavali Chakravarti, Xiaoying Shang, Denise J. Spring, Yanru Wang, Ronald A. DePinho

    Published 2023
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  16. 16
    Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer

    Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer by Pat Gulhati, Aislyn Schalck, Shan Jiang, Xiaoying Shang, Chang‐Jiun Wu, Pingping Hou, Sharia Hernández Ruiz, Luisa M. Solis Soto, Edwin R. Parra, Haoqiang Ying, Jincheng Han, Prasenjit Dey, Jun Li, Pingna Deng, Emi Sei, Dean Y. Maeda, John A. Zebala, Denise J. Spring, Michael P. Kim, Huamin Wang, Anirban Maitra, Dirk F. Moore, Karen Clise-Dwyer, Yanru Wang, Nicholas E. Navin, Ronald A. DePinho

    Published 2022
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  17. 17
    SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

    SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression by Zhihu Ding, Chang‐Jiun Wu, Gerald C. Chu, Yonghong Xiao, Dennis Chun‐Yu Ho, Jingfang Zhang, Samuel R. Perry, Emma Labrot, Xiaoqiu Wu, Rosina T. Lis, Yujin Hoshida, D. Hiller, Baoli Hu, Shan Jiang, Hongwu Zheng, Alexander H. Stegh, Kenneth L. Scott, Sabina Signoretti, Nabeel Bardeesy, Yanru Wang, David E. Hill, Todd R. Golub, Meir J. Stampfer, Wing H. Wong, Massimo Loda, Lorelei A. Mucci, Lynda Chin, Ronald A. DePinho

    Published 2011
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  18. 18
    Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

    Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer by Avnish Kapoor, Wantong Yao, Haoqiang Ying, Sujun Hua, Alison Liewen, Qiuyun Wang, Yi Zhong, Chang‐Jiun Wu, Anguraj Sadanandam, Baoli Hu, Qing Chang, Gerald C. Chu, Ramsey Al-Khalil, Shan Jiang, Hongai Xia, Eliot Fletcher-Sananikone, Carol S. Lim, Gillian I. Horwitz, Andrea Viale, Piergiorgio Pettazzoni, Nora Sánchez, Huamin Wang, Alexei Protopopov, Jianhua Zhang, Timothy P. Heffernan, Randy L. Johnson, Lynda Chin, Yanru Wang, Giulio Draetta, Ronald A. DePinho

    Published 2014
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  19. 19
    Telomere dysfunction instigates inflammation in inflammatory bowel disease

    Telomere dysfunction instigates inflammation in inflammatory bowel disease by Deepavali Chakravarti, Rumi Lee, Asha S. Multani, Andrea Santoni, Zachery Keith, Wen‐Hao Hsu, Kyle Chang, Laura Reyes-Uribe, Asif Rashid, Chang‐Jiun Wu, Jun Li, Jiexin Zhang, Hong Seok Shim, Krishna Chandra, Pingna Deng, Denise J. Spring, Ole Haagen Nielsen, Lene Riis, Kavya Kelagere Mayigegowda, Sarah E. Blutt, Jianhua Zhang, Mamoun Younes, Andrew Dupont, Selvi Thirumurthi, Eduardo Vilar, Mary K. Estes, Simona Colla, Noah F. Shroyer, Ronald A. DePinho

    Published 2021
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  20. 20
    ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

    ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma by Matteo Marchesini, Yamini Ogoti, Elena Fiorini, Anıl Aktaş Samur, Luigi Nezi, Marianna D’Anca, Paola Storti, Mehmet Samur, Irene Gañán‐Gómez, Maria Teresa Fulciniti, Nipun A. Mistry, Shan Jiang, Naran Bao, Valentina Marchica, Antonino Neri, Carlos E. Bueso‐Ramos, Chang‐Jiun Wu, Li Zhang, Han Liang, Xinxin Peng, Nicola Giuliani, Giulio Draetta, Karen Clise-Dwyer, Hagop M. Kantarjian, Nikhil C. Munshi, Robert Z. Orlowski, Guillermo Garcia‐Manero, Ronald A. DePinho, Simona Colla

    Published 2017
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