Ngā hua rapu - Brian L. Hodous

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  1. 1
    First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway

    First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway mā Margit Hagel, Chandra Miduturu, Michael P. Sheets, Nooreen Rubin, Weifan Weng, Nicolas Stransky, Neil Bifulco, Joseph L. Kim, Brian L. Hodous, Natasja Brooijmans, Adam Shutes, Christopher Winter, Christoph Lengauer, Nancy E. Kohl, Timothy J. Guzi

    I whakaputaina 2015
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    Artigo
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  2. 2
    Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

    Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines mā Marc Payton, Tammy L. Bush, Grace Chung, Beth Ziegler, Patrick Eden, Patricia McElroy, Sandra L. Ross, Victor J. Cee, Holly L. Deak, Brian L. Hodous, Hanh Nho Nguyen, Philip R. Olivieri, Karina Romero, Laurie B. Schenkel, Annette Bak, Mary K. Stanton, Isabelle Dussault, Vinod F. Patel, Stephanie Geuns-Meyer, Robert Radinsky, Richard Kendall

    I whakaputaina 2010
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    Artigo
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  3. 3
    Discovery of <i>N</i>-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines

    Discovery of <i>N</i>-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor... mā Stephanie Geuns-Meyer, Victor J. Cee, Holly L. Deak, Bingfan Du, Brian L. Hodous, Hanh Nho Nguyen, Philip R. Olivieri, Laurie B. Schenkel, Karina R. Vaida, Paul S. Andrews, Annette Bak, Xuhai Be, Pedro J. Beltran, Tammy L. Bush, Mary K. Chaves, Grace Chung, Yang Dai, Patrick Eden, Kelly Hanestad, Liyue Huang, Min-Hwa Jasmine Lin, Jin Tang, Beth Ziegler, Robert Radinsky, Richard Kendall, Vinod F. Patel, Marc Payton

    I whakaputaina 2015
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    Artigo
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  4. 4
    A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations

    A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations mā Erica Evans, Alexandra K. Gardino, Joseph L. Kim, Brian L. Hodous, Adam Shutes, Alison Davis, Xing Julia Zhu, Oleg Schmidt-Kittler, Doug Wilson, Kevin Wilson, Lucian DiPietro, Yulian Zhang, Natasja Brooijmans, Timothy P. LaBranche, Agnieszka Woźniak, Yemarshet K. Gebreyohannes, Patrick Schöffski, Michael C. Heinrich, Daniel J. DeAngelo, Steven P. Miller, Beni B. Wolf, Nancy E. Kohl, Timothy J. Guzi, NICHOLAS B. LYDON, Andy Boral, Christoph Lengauer

    I whakaputaina 2017
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  5. 5
    Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases

    Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases mā Richard D. Caldwell, Hui Qiu, Ben Askew, Andrew T. Bender, Nadia Brügger, Montserrat Camps, Mohanraj Dhanabal, Vikram Dutt, Thomas Eichhorn, A.S. Gardberg, Andreas Goutopoulos, Roland Grenningloh, Jared Head, Brian Healey, Brian L. Hodous, Bayard R. Huck, Theresa Johnson, Christopher C. Jones, Reinaldo Jones, Igor Mochalkin, Federica Morandi, Thi Kim Ngan Nguyen, Michael Meyring, Justin R. Potnick, Dusica Santos, Ralf Schmidt, Brian Sherer, Adam Shutes, Klaus Urbahns, Ariele Viacava Follis, Ansgar Wegener, Simone C. Zimmerli, Lesley Liu‐Bujalski

    I whakaputaina 2019
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    Artigo
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