Søgeresultater - Brian Bigger

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  1. 1
    The role of innate immunity in mucopolysaccharide diseases

    The role of innate immunity in mucopolysaccharide diseases af Helen Parker, Brian Bigger

    Udgivet 2018
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  2. 2
    Delivering gene therapy for mucopolysaccharide diseases

    Delivering gene therapy for mucopolysaccharide diseases af Shaun Wood, Brian Bigger

    Udgivet 2022
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  3. 3
    Innate Immunity in Mucopolysaccharide Diseases

    Innate Immunity in Mucopolysaccharide Diseases af Oriana Mandolfo, Helen Parker, Brian Bigger

    Udgivet 2022
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  4. 4
    Advances in therapies for neurological lysosomal storage disorders

    Advances in therapies for neurological lysosomal storage disorders af Stuart Ellison, Helen Parker, Brian Bigger

    Udgivet 2023
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  5. 5
    Anatomical changes and pathophysiology of the brain in mucopolysaccharidosis disorders

    Anatomical changes and pathophysiology of the brain in mucopolysaccharidosis disorders af Brian Bigger, David J. Begley, Daniela Virgintino, Alexey V. Pshezhetsky

    Udgivet 2018
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  6. 6
    An araC-controlled Bacterialcre Expression System to Produce DNA Minicircle Vectors for Nuclear and Mitochondrial Gene Therapy

    An araC-controlled Bacterialcre Expression System to Produce DNA Minicircle Vectors for Nuclear and Mitochondrial Gene Therapy af Brian Bigger, Oleg Tolmachov, Jean-Marc Collombet, Michalis Fragkos, Iwona Palaszewski, Charles Coutelle

    Udgivet 2001
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  7. 7
    Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation

    Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation af Fiona L. Wilkinson, Ana Sergijenko, Kia Langford‐Smith, Marcelina Malinowska, Robert Wynn, Brian Bigger

    Udgivet 2013
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  8. 8
    Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice

    Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice af Ádám Dénes, Fiona L. Wilkinson, Brian Bigger, Michael Chu, Nancy J. Rothwell, Stuart M. Allan

    Udgivet 2013
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  9. 9
    Hepatic stem cells: from inside and outside the liver?

    Hepatic stem cells: from inside and outside the liver? af Malcolm Alison, Pamela Vig, Francesco Paolo Russo, Brian Bigger, Eunice Amofah, Michael Themis, Stuart J. Forbes

    Udgivet 2004
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  10. 10
    The Inflammation in the Cytopathology of Patients With Mucopolysaccharidoses- Immunomodulatory Drugs as an Approach to Therapy

    The Inflammation in the Cytopathology of Patients With Mucopolysaccharidoses- Immunomodulatory Drugs as an Approach to Therapy af Anna‐Maria Wiesinger, Brian Bigger, Roberto Giugliani, Maurizio Scarpa, Tobias Moser, Christina Lampe, Christoph Kampmann, Florian B. Lagler

    Udgivet 2022
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  11. 11
    RETRACTED: An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis

    RETRACTED: An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis af Anna‐Maria Wiesinger, Brian Bigger, Roberto Giugliani, Christina Lampe, Maurizio Scarpa, Tobias Moser, Christoph Kampmann, Georg Zimmermann, Florian B. Lagler

    Udgivet 2023
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  12. 12
    RETRACTED: Wiesinger et al. An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis. Pharmaceutics 2023, 15, 1565

    RETRACTED: Wiesinger et al. An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis. Pharmaceutics 2023, 15, 1565 af Anna‐Maria Wiesinger, Brian Bigger, Roberto Giugliani, Christina Lampe, Maurizio Scarpa, Tobias Moser, Christoph Kampmann, Georg Zimmermann, Florian B. Lagler

    Udgivet 2023
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  13. 13
    Development of a novel tool for individual treatment trials in mucopolysaccharidosis

    Development of a novel tool for individual treatment trials in mucopolysaccharidosis af Anna‐Maria Wiesinger, Brian Bigger, Roberto Giugliani, Christina Lampe, Maurizio Scarpa, Tobias Moser, Christoph Kampmann, Georg Zimmermann, Florian B. Lagler

    Udgivet 2024
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  14. 14
    Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma

    Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma af William J. Griffiths, Peter J. Crick, Yuchen Wang, Michael Ogundare, Karin Tuschl, Andrew A. M. Morris, Brian Bigger, Peter T. Clayton, Yuqin Wang

    Udgivet 2012
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  15. 15
    Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms

    Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms af Hélène F.E. Gleitz, Ai Yin Liao, James Cook, Samuel Rowlston, Gabriella Forte, Zelpha D’Souza, Claire O’Leary, Rebecca Holley, Brian Bigger

    Udgivet 2018
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  16. 16
    Hematopoietic stem cell transplantation improves the high incidence of neutralizing allo-antibodies observed in Hurler's syndrome after pharmacological enzyme replacement therapy

    Hematopoietic stem cell transplantation improves the high incidence of neutralizing allo-antibodies observed in Hurler's syndrome after pharmacological enzyme replacement therapy af M. A. Saif, Brian Bigger, Karen E. Brookes, Jean Mercer, Karen Tylee, Heather J. Church, Denise Bonney, Simon Jones, J. E. Wraith, Robert Wynn

    Udgivet 2012
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  17. 17
    Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and Increased N-Sulfotransferase Activity in Mice Lacking α-l-iduronidase

    Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and Increased N-Sulfotransferase Activity in Mice Lacking α-l-iduronidase af Rebecca Holley, Audrey Deligny, Wei Wei, H. Angharad Watson, Milady R. Niñonuevo, Anders Dagälv, Julie A. Leary, Brian Bigger, Lena Kjellén, Catherine L.R. Merry

    Udgivet 2011
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  18. 18
    Sleep disordered breathing in mucopolysaccharidosis I: a multivariate analysis of patient, therapeutic and metabolic correlators modifying long term clinical outcome

    Sleep disordered breathing in mucopolysaccharidosis I: a multivariate analysis of patient, therapeutic and metabolic correlators modifying long term clinical outcome af Abhijit Pal, Eveline J. Langereis, Muhammad A. Saif, Jean Mercer, Heather J. Church, Karen Tylee, Robert Wynn, Frits A. Wijburg, Simon Jones, Iain Bruce, Brian Bigger

    Udgivet 2015
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  19. 19
    Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10year combined experience of 2 centres

    Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10year combined experience of 2 centres af Arunabha Ghosh, Weston P. Miller, Paul J. Orchard, Simon Jones, Jean Mercer, Heather J. Church, Karen Tylee, Troy C. Lund, Brian Bigger, Jakub Tolar, Robert Wynn

    Udgivet 2016
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  20. 20
    Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice

    Hematopoietic Stem Cell and Gene Therapy Corrects Primary Neuropathology and Behavior in Mucopolysaccharidosis IIIA Mice af Alex Langford-Smith, Fiona L. Wilkinson, Kia Langford‐Smith, Rebecca Holley, Ana Sergijenko, Steven J. Howe, William Bennett, Simon Jones, JE Wraith, Catherine L.R. Merry, Robert Wynn, Brian Bigger

    Udgivet 2012
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