Ngā hua rapu - Bo Hee Shin

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  1. 1
    Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations

    Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations mā Jaebong Jang, Ciric To, Dries J.H. De Clercq, Eunyoung Park, Charles M. Ponthier, Bo Hee Shin, Mierzhati Mushajiang, Radosław P. Nowak, Eric S. Fischer, Michael J. Eck, Pasi A. Jänne, Nathanael S. Gray

    I whakaputaina 2020
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    Artigo
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  2. 2
    Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors

    Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors mā Dries J.H. De Clercq, David E. Heppner, Ciric To, Jaebong Jang, Eunyoung Park, Cai‐Hong Yun, Mierzhati Mushajiang, Bo Hee Shin, Thomas W. Gero, David A. Scott, Pasi A. Jänne, Michael J. Eck, Nathanael S. Gray

    I whakaputaina 2019
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    Artigo
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  3. 3
    Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

    Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites mā Florian Wittlinger, David E. Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K. Rana, Anna M. Schmoker, Tyler S. Beyett, Lena M. Berger, Benedict‐Tilman Berger, Nicolas Bauer, James D. Vasta, Cesear Corona, Matthew B. Robers, Stefan Knapp, Pasi A. Jänne, Michael J. Eck, Stefan Laufer

    I whakaputaina 2021
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    Artigo
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  4. 4
    Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor

    Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor mā Ciric To, Jaebong Jang, Ting Chen, Eunyoung Park, Mierzhati Mushajiang, Dries J.H. De Clercq, Man Xu, Stephen Wang, Michael D. Cameron, David E. Heppner, Bo Hee Shin, Thomas W. Gero, Annan Yang, Suzanne E. Dahlberg, Kwok‐Kin Wong, Michael J. Eck, Nathanael S. Gray, Pasi A. Jänne

    I whakaputaina 2019
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    Artigo
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  5. 5
    An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer

    An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer mā Ciric To, Tyler S. Beyett, Jaebong Jang, William W. Feng, Magda Bahcall, Heidi M. Haikala, Bo Hee Shin, David E. Heppner, Jaimin K. Rana, Brittaney A. Leeper, Kara M. Soroko, Michael J. Poitras, Prafulla C. Gokhale, Yoshihisa Kobayashi, Kamal Wahid, Kari J. Kurppa, Thomas W. Gero, Michael D. Cameron, Atsuko Ogino, Mierzhati Mushajiang, Chunxiao Xu, Yanxi Zhang, David A. Scott, Michael J. Eck, Nathanael S. Gray, Pasi A. Jänne

    I whakaputaina 2022
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  6. 6
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway mā Kari J. Kurppa, Yao Liu, Ciric To, Tinghu Zhang, Mengyang Fan, Amir Vajdi, Erik H. Knelson, Yingtian Xie, Klothilda Lim, Paloma Cejas, Andrew Portell, Patrick H. Lizotte, Scott B. Ficarro, Shuai Li, Ting Chen, Heidi M. Haikala, Haiyun Wang, Magda Bahcall, Yang Gao, Sophia Z. Shalhout, Steffen Boettcher, Bo Hee Shin, Tran C. Thai, Margaret K. Wilkens, Michelle Tillgren, Mierzhati Mushajiang, Man Xu, Jihyun Choi, Arrien A. Bertram, Benjamin L. Ebert, Rameen Beroukhim, Pratiti Bandopadhayay, Mark M. Awad, Prafulla C. Gokhale, Paul T. Kirschmeier, Jarrod A. Marto, Fernando D. Camargo, Rizwan Haq, Cloud P. Paweletz, Kwok‐Kin Wong, David A. Barbie, Henry W. Long, Nathanael S. Gray, Pasi A. Jänne

    I whakaputaina 2020
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    Artigo
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