檢索結果 - Benjamin G. Tehan
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Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits 由 Jon Palacios-Filardo, Matt Udakis, Giles A. Brown, Benjamin G. Tehan, Miles Congreve, Pradeep J. Nathan, Alastair Brown, Jack R. Mellor
出版 2021Artigo -
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Discovery of 1,2,4-Triazine Derivatives as Adenosine A<sub>2A</sub> Antagonists using Structure Based Drug Design 由 Miles Congreve, Stephen P. Andrews, A.S. Dore, Kaspar Hollenstein, Edward Hurrell, Christopher J. Langmead, Jonathan S. Mason, Irene W. Ng, Benjamin G. Tehan, Andrei Zhukov, Malcolm Weir, Fiona H. Marshall
出版 2012Artigo -
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Biophysical Fragment Screening of the β<sub>1</sub>-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design 由 J.A. Christopher, Jason Brown, A.S. Dore, James C. Errey, Markus Koglin, Fiona H. Marshall, David G. Myszka, Rebecca L. Rich, Christopher G. Tate, Benjamin G. Tehan, Tony Warne, Miles Congreve
出版 2013Artigo -
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Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis 由 Mathieu Rappas, A. Ali, K.A. Bennett, Jason Brown, S.J. Bucknell, Miles Congreve, Roger Cooke, G. Cseke, Chris de Graaf, A.S. Dore, James C. Errey, Ali Jazayeri, Fiona H. Marshall, Jonathan Mason, Richard F. Mould, Jayesh C. Patel, Benjamin G. Tehan, Malcolm Weir, J.A. Christopher
出版 2019Artigo -
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From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease 由 Alastair Brown, Sophie J. Bradley, Fiona H. Marshall, Giles A. Brown, K.A. Bennett, Jason Brown, Julie E. Cansfield, David M. Cross, Chris de Graaf, Brian D. Hudson, Louis Dwomoh, João M. Dias, James C. Errey, Edward Hurrell, Jan Liptrot, Giulio Mattedi, Colin Molloy, Pradeep J. Nathan, Krzysztof Okrasa, Greg Osborne, Jayesh C. Patel, Mark Pickworth, N.J. Robertson, Shahram Shahabi, Christoffer Bundgaard, Keith G. Phillips, Lisa M. Broad, Anushka V. Goonawardena, Stephen R. Morairty, Michael Browning, Francesca Perini, Gerard R. Dawson, J.F.W. Deakin, R T Smith, Patrick M. Sexton, Julie Warneck, Mary Vinson, Tim Tasker, Benjamin G. Tehan, Barry Teobald, Arthur Christopoulos, Christopher J. Langmead, Ali Jazayeri, Roger Cooke, Prakash Rucktooa, Miles Congreve, Malcolm Weir, Andrew B. Tobin
出版 2021Artigo
相關主題
Biochemistry
Receptor
Chemistry
Biology
G protein-coupled receptor
Medicine
Ligand (biochemistry)
Pharmacology
Agonist
Gene
Stereochemistry
Adenosine receptor
Computational biology
Drug discovery
Genetics
Neuroscience
Acetylcholine
Adenosine
Bioinformatics
Cholinergic
Combinatorial chemistry
Computer science
Docking (animal)
Drug
Druggability
Enzyme
In vitro
Lead compound
Muscarinic acetylcholine receptor
Nursing