Search Results - Astrid Vallès

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  1. 1
    Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia

    Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia by Dorien A. Maas, Astrid Vallès, Gerard J.M. Martens

    Published 2017
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    Revisão
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  2. 2
    AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models

    AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models by Elisabeth A. Spronck, Cynthia Brouwers, Astrid Vallès, Martin de Haan, Harald Petry, S J van Deventer, Pavlina Konstantinova, Melvin M. Evers

    Published 2019
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    Artigo
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  3. 3
    AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes

    AAV5-miHTT Lowers Huntingtin mRNA and Protein without Off-Target Effects in Patient-Derived Neuronal Cultures and Astrocytes by Sonay Keskin, Cynthia Brouwers, Marina Sogorb-González, Raygene Martier, Josse A. Depla, Astrid Vallès, S J van Deventer, Pavlina Konstantinova, Melvin M. Evers

    Published 2019
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    Artigo
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  4. 4
    Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

    Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia by Dorien A. Maas, Vivian D. Eijsink, Marcia Spoelder, Josephus A. van Hulten, Peter De Weerd, Judith R. Homberg, Astrid Vallès, Brahim Nait‐Oumesmar, Gerard J.M. Martens

    Published 2020
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    Artigo
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  5. 5
    Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington disease models

    Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington disease models by Marina Sogorb-González, Christian Landles, Nicholas S. Caron, Anouk Stam, Georgina F Osborne, Michael R. Hayden, David Howland, Sander van Deventer, Gillian P. Bates, Astrid Vallès, Melvin M. Evers

    Published 2024
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    Artigo
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  6. 6
    Intrastriatal Administration of AAV5-miHTT in Non-Human Primates and Rats Is Well Tolerated and Results in miHTT Transgene Expression in Key Areas of Huntington Disease Pathology

    Intrastriatal Administration of AAV5-miHTT in Non-Human Primates and Rats Is Well Tolerated and Results in miHTT Transgene Expression in Key Areas of Huntington Disease Pathology by Elisabeth A. Spronck, Astrid Vallès, Margit H. Lampen, Paula S. Montenegro-Miranda, Sonay Keskin, Liesbeth Heijink, Melvin M. Evers, Harald Petry, S. J. H. Van Deventer, Pavlina Konstantinova, Martin de Haan

    Published 2021
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    Artigo
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  7. 7
    AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model

    AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model by Melvin M. Evers, Jana Miniarikova, Štefan Juhás, Astrid Vallès, Božena Bohuslavová, Jana Juhásová, Helena Kupcová Skalníková, Petr Vodička, Ivona Valeková, Cynthia Brouwers, Bas Blits, Jacek Lubelski, Hana Kovářová, Zdeňka Ellederová, S J van Deventer, Harald Petry, Jan Motlík, Pavlina Konstantinova

    Published 2018
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  8. 8
    Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability

    Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability by Marjolein H. Willemsen, Astrid Vallès, Laurens A. M. H. Kirkels, Mathilde Mastebroek, Nikkie Olde Loohuis, Aron Kos, W.M. Wissink-Lindhout, Arjan P.M. de Brouwer, Willy M. Nillesen, Rolph Pfundt, Muriel Holder‐Espinasse, Louis Vallée, Joris Andrieux, Marjolein C. Coppens‐Hofman, Hanneke Rensen, Ben C.J. Hamel, Hans van Bokhoven, Armaz Aschrafi, Tjitske Kleefstra

    Published 2011
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