檢索結果 - Angela N. Koehler

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  1. 1
    A complex task? Direct modulation of transcription factors with small molecules

    A complex task? Direct modulation of transcription factors with small molecules 由 Angela N. Koehler

    出版 2010
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  2. 2
    Transcription Factor Inhibition: Lessons Learned and Emerging Targets

    Transcription Factor Inhibition: Lessons Learned and Emerging Targets 由 Andrew Chen, Angela N. Koehler

    出版 2020
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  3. 3
    A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2

    A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2 由 Zhihong Yang, Angela N. Koehler, Li Wang

    出版 2016
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  4. 4
    Small-molecule microarrays as tools in ligand discovery

    Small-molecule microarrays as tools in ligand discovery 由 Arturo J. Vegas, Jason H. Fuller, Angela N. Koehler

    出版 2008
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  5. 5
    Small Molecule Microarrays Enable the Discovery of Compounds That Bind the Alzheimer’s Aβ Peptide and Reduce its Cytotoxicity

    Small Molecule Microarrays Enable the Discovery of Compounds That Bind the Alzheimer’s Aβ Peptide and Reduce its Cytotoxicity 由 Jermont Chen, Anne H. Armstrong, Angela N. Koehler, Michael H. Hecht

    出版 2010
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  6. 6
    Fluorous‐Based Small‐Molecule Microarrays for the Discovery of Histone Deacetylase Inhibitors

    Fluorous‐Based Small‐Molecule Microarrays for the Discovery of Histone Deacetylase Inhibitors 由 Arturo J. Vegas, James E. Bradner, Weiping Tang, Olivia M. McPherson, Edward F. Greenberg, Angela N. Koehler, Stuart L. Schreiber

    出版 2007
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  7. 7
    A one-bead, one-stock solution approach to chemical genetics: part 2

    A one-bead, one-stock solution approach to chemical genetics: part 2 由 Paul A. Clemons, Angela N. Koehler, Bridget K. Wagner, Timothy G Sprigings, David R. Spring, Randall W. King, Stuart L. Schreiber, Michael A. Foley

    出版 2001
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  8. 8
    Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma

    Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma 由 Anja Deutzmann, Delaney K. Sullivan, Renumathy Dhanasekaran, Wei Li, Xinyu Chen, Ling Tong, Wadie D. Mahauad‐Fernandez, John Bell, Adriane Mosley, Angela N. Koehler, Yulin Li, Dean W. Felsher

    出版 2024
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  9. 9
    A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein

    A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein 由 Marius S. Pop, Nicolas Stransky, Colin W. Garvie, Jean‐Philippe Theurillat, Emily C. Hartman, Timothy A. Lewis, Cheng Zhong, Elizabeth K. Culyba, Fallon Lin, Douglas S. Daniels, Raymond Pagliarini, Lucienne Ronco, Angela N. Koehler, Levi A. Garraway

    出版 2014
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  10. 10
    A small molecule that binds Hedgehog and blocks its signaling in human cells

    A small molecule that binds Hedgehog and blocks its signaling in human cells 由 Benjamin Z. Stanton, Lee F. Peng, Nicole Maloof, Kazuo Nakai, Xiang Wang, Jay Duffner, Kennedy M Taveras, Joel M. Hyman, Sam W. Lee, Angela N. Koehler, James Chen, Julia L Fox, Anna Mandinova, Stuart L. Schreiber

    出版 2009
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  11. 11
    Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

    Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling 由 Yingwei Mao, Xuecai Ge, Christopher L. Frank, Jon M. Madison, Angela N. Koehler, Mary Kathryn Doud, Carlos Tassa, Erin M. Berry, Takahiro Soda, Karun K. Singh, Travis L. Biechele, Tracey L. Petryshen, Randall T. Moon, Stephen J. Haggarty, Li-Huei Tsai

    出版 2009
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  12. 12
    Identifying the proteins to which small-molecule probes and drugs bind in cells

    Identifying the proteins to which small-molecule probes and drugs bind in cells 由 Shao‐En Ong, Monica Schenone, Adam A. Margolin, Xiaoyu Li, Kathy Do, Mary Kathryn Doud, D.R. Mani, Letian Kuai, Xiang Wang, John L. Wood, Nicola Tolliday, Angela N. Koehler, Lisa A. Marcaurelle, Todd R. Golub, Robert J. Gould, Stuart L. Schreiber, Steven A. Carr

    出版 2009
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  13. 13
    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery 由 Natalie Boehnke, Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan, Danny Rosenberg, Charles H. Adelmann, Raghu R. Chivukula, Namita Nabar, Adam G. Berger, Nicholas G. Lamson, Jaime H. Cheah, Hojun Li, Jennifer A. Roth, Angela N. Koehler, Paula T. Hammond

    出版 2022
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  14. 14
    Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

    Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors 由 João Seixas, Bárbara B. Sousa, Marta C. Marques, Ana Guerreiro, Rui Traquete, Tiago Rodrigues, Inês S. Albuquerque, Marcos F. Q. Sousa, Ana R. Lemos, Pedro M. F. Sousa, Tiago M. Bandeiras, Di Wu, Shelby K. Doyle, Carol V. Robinson, Angela N. Koehler, Francisco Corzana, Pedro M. Matias, Gonçalo J. L. Bernardes

    出版 2020
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  15. 15
    Targeted degradation of CDK9 potently disrupts the MYC-regulated network

    Targeted degradation of CDK9 potently disrupts the MYC-regulated network 由 Mohammed A. Toure, Keisuke Motoyama, Yichen Xiang, Julie Urgiles, Florian Kabinger, Ann-Sophie Koglin, Ramya S. Iyer, Kaitlyn Gagnon, Amruth Kumar, Samuel Ojeda, Drew A. Harrison, Matthew G. Rees, Jennifer A. Roth, Christopher J. Ott, Richard P. Schiavoni, Charles A. Whittaker, Stuart S. Levine, Forest M. White, Eliezer Calo, André Richters, Angela N. Koehler

    出版 2025
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  16. 16
    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

    Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics 由 Luc de Waal, Timothy A. Lewis, Matthew G. Rees, Aviad Tsherniak, Xiaoyun Wu, Peter S. Choi, Lara Gechijian, Christina R. Hartigan, Patrick W. Faloon, Mark J. Hickey, Nicola Tolliday, Steven A. Carr, Paul A. Clemons, Benito Muñoz, Bridget K. Wagner, Alykhan F. Shamji, Angela N. Koehler, Monica Schenone, Alex B. Burgin, Stuart L. Schreiber, Heidi Greulich, Matthew Meyerson

    出版 2015
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  17. 17
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells

    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells 由 Vivian Morris, Dahai Wang, Zhiheng Li, William Marion, Travis K. Hughes, Patricia Sousa, Taku Harada, Shannan Ho Sui, Sergey Naumenko, Jérémie Kalfon, Prerana Sensharma, Marcelo Falchetti, Renan Vinicius da Silva, Tito Candelli, Pauline Schneider, Thanasis Margaritis, Frank C. P. Holstege, Yana Pikman, Marian H. Harris, Ronald W. Stam, Stuart H. Orkin, Angela N. Koehler, Alex K. Shalek, Trista E. North, Maxim Pimkin, George Q. Daley, Edroaldo Lummertz da Rocha, R. Grant Rowe

    出版 2022
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  18. 18
    Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription

    Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription 由 Nicholas B. Struntz, Andrew Chen, Anja Deutzmann, Robert M. Wilson, Eric Stefan, Helen L. Evans, Maricela A. Ramirez, Tong Liang, Francisco Caballero, Mattheus H. E. Wildschut, Dylan V. Neel, David B. Freeman, Marius S. Pop, Marie McConkey, Sandrine Muller, Brice H. Curtin, Hanna Tseng, Kristen R. Frombach, Vincent L. Butty, Stuart S. Levine, Clémentine Féau, Sarah Elmiligy, Jiyoung A. Hong, Timothy A. Lewis, Amedeo Vetere, Paul A. Clemons, Scott Malstrom, Benjamin L. Ebert, Charles Y. Lin, Dean W. Felsher, Angela N. Koehler

    出版 2019
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  19. 19
    Towards patient-based cancer therapeutics

    Towards patient-based cancer therapeutics 由 Stuart L. Schreiber, Alykhan F. Shamji, Paul A. Clemons, Cindy Hon, Angela N. Koehler, Benito Muñoz, Michelle Palmer, Andrew M. Stern, Bridget K. Wagner, Scott Powers, Scott W. Lowe, Xuecui Guo, A. Krasnitz, Eric T. Sawey, Raffaella Sordella, Lincoln Stein, Lloyd C. Trotman, Andrea Califano, Riccardo Dalla‐Favera, Adolfo A. Ferrando, Antonio Iavarone, Laura Pasqualucci, José Silva, Brent R. Stockwell, William C. Hahn, Lynda Chin, Ronald A. DePinho, Jesse S. Boehm, Shuba Gopal, Alan Huang, David E. Root, Barbara A. Weir, Daniela S. Gerhard, Jean C. Zenklusen, Michael G. Roth, Michael A. White, John D. Minna, John B. MacMillan, Bruce A. Posner

    出版 2010
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  20. 20
    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors 由 André Richters, Shelby K. Doyle, David B. Freeman, Christina Lee, Becky Leifer, Sajjeev Jagannathan, Florian Kabinger, Jošt Vrabič Koren, Nicholas B. Struntz, Julie Urgiles, Ryan A. Stagg, Brice H. Curtin, Deep Chatterjee, Sebastian Mathea, Peter Mikochik, Tamara D. Hopkins, Hua Gao, Jonathan R. Branch, Hong Xin, Lori Westover, Gilles Bignan, Brent Rupnow, Kristen L. Karlin, Calla M. Olson, Thomas F. Westbrook, Joseph P. Vacca, Chris M. Wilfong, B. Wesley Trotter, Douglas C. Saffran, Norbert Bischofberger, Stefan Knapp, Joshua W. Russo, Ian Hickson, James R. Bischoff, Marco M. Gottardis, Steven P. Balk, Charles Y. Lin, Marius S. Pop, Angela N. Koehler

    出版 2020
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