Search Results - Amanda McQuade

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  1. 1
    Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk

    Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk by Amanda McQuade, Mathew Blurton‐Jones

    Published 2019
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  2. 2
    Development and validation of a simplified method to generate human microglia from pluripotent stem cells

    Development and validation of a simplified method to generate human microglia from pluripotent stem cells by Amanda McQuade, Morgan Coburn, Christina Tu, Jonathan Hasselmann, Hayk Davtyan, Mathew Blurton‐Jones

    Published 2018
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  3. 3
    Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

    Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease by Shankar J. Chinta, Georgia Woods, Marco Demaria, Anand Rane, Ying Zou, Amanda McQuade, Subramanian Rajagopalan, Chandani Limbad, David T. Madden, Judith Campisi, Julie K. Andersen

    Published 2018
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  4. 4
    Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain

    Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain by Yang You, Satoshi Muraoka, Mark P. Jedrychowski, Jianqiao Hu, Amanda McQuade, Tracy L. Young‐Pearse, Roshanak Aslebagh, Scott A. Shaffer, Steven P. Gygi, Mathew Blurton‐Jones, Wayne W. Poon, Tsuneya Ikezu

    Published 2022
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  5. 5
    TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

    TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia by Amit Jairaman, Amanda McQuade, Alberto Granzotto, You Jung Kang, Jean Paul Chadarevian, Sunil Gandhi, Ian Parker, Ian F. Smith, Hansang Cho, Stefano L. Sensi, Shivashankar Othy, Mathew Blurton‐Jones, Michael D. Cahalan

    Published 2022
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  6. 6
    CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning

    CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning by Olivia M. Teter, Amanda McQuade, Venus Hagan, W. Liang, Nina M. Dräger, Sydney M. Sattler, Brandon B. Holmes, Vincent Cele Castillo, Vasileios Papakis, Kun Leng, Steven Boggess, Tomasz J. Nowakowski, James A. Wells, Martin Kampmann

    Published 2025
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  7. 7
    Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at <i>APOE</i>

    Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at <i>APOE</i> by Tong‐Fei Liu, Bing Zhu, Yan Liu, Xiaoming Zhang, Jun Yin, Xiaoguang Li, Lu-Lin Jiang, Andrew Hodges, Sara Brin Rosenthal, Lisa Zhou, Joel Yancey, Amanda McQuade, Mathew Blurton‐Jones, Rudolph E. Tanzi, Timothy Y. Huang, Huaxi Xu

    Published 2020
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  8. 8
    Genetic contribution to microglial activation in schizophrenia

    Genetic contribution to microglial activation in schizophrenia by Marja Koskuvi, Elina Pörsti, Tristen Hewitt, Noora Räsänen, Ying‐Chieh Wu, Kalevi Trontti, Amanda McQuade, Shringaa Kalyanaraman, Ilkka Ojansuu, Olli Vaurio, Tyrone D. Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana Suvisaari, Jaakko Kaprio, Mathew Blurton‐Jones, Iiris Hovatta, Markku Lähteenvuo, Taisia Rõlova, Šárka Lehtonen, Jari Tiihonen, Jari Koıstınaho

    Published 2024
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  9. 9
    Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo

    Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo by Jonathan Hasselmann, Morgan Coburn, Whitney England, Dario X. Figueroa Velez, Sepideh Kiani Shabestari, Christina Tu, Amanda McQuade, Mahshad Kolahdouzan, Karla Echeverria, Christel Claes, Taylor Nakayama, Ricardo Azevedo, Nicole G. Coufal, Claudia Z. Han, B. Cummings, Hayk Davtyan, Christopher K. Glass, Luke M. Healy, Sunil Gandhi, Robert C. Spitale, Mathew Blurton‐Jones

    Published 2019
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  10. 10
    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice by Sepideh Kiani Shabestari, Samuel Morabito, Emma Danhash, Amanda McQuade, Jessica Sanchez, Emily Miyoshi, Jean Paul Chadarevian, Christel Claes, Morgan Coburn, Jonathan Hasselmann, Jorge Luis Silva Hidalgo, Kayla Nhi Tran, Alessandra Cadete Martini, Winston Chang Rothermich, Jesse R. Pascual, Elizabeth Head, David Hume, Clare Pridans, Hayk Davtyan, Vivek Swarup, Mathew Blurton‐Jones

    Published 2022
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  11. 11
    Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

    Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease by Amanda McQuade, You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn, Sepideh Kiani Shabestari, Jean Paul Chadarevian, Gianna Fote, Christina Tu, Emma Danhash, Jorge Sá Silva, Eric Martínez, Carl W. Cotman, G. Aleph Prieto, Leslie M. Thompson, Joan S. Steffan, Ian F. Smith, Hayk Davtyan, Michael D. Cahalan, Hansang Cho, Mathew Blurton‐Jones

    Published 2020
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  12. 12
    Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features

    Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features by Ileana Lorenzini, Eric Alsop, Jennifer Lévy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan S. Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen‐Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu‐Ting Hung, Justin K. Ichida, Robert Bowser, Tara L. Spires‐Jones, Mathew Blurton‐Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren‐Jensen, Rita Sattler

    Published 2023
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