Výsledky vyhledávání - Alison D. Axtman

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  1. 1
    Development of a Second-Generation, <i>In Vivo</i> Chemical Probe for PIKfyve

    Development of a Second-Generation, <i>In Vivo</i> Chemical Probe for PIKfyve Autor Sophia M. Min, Frances M. Bashore, Jeffrey L. Smith, Tammy M. Havener, Stefanie Howell, Haoxi Li, Rafael M. Couñago, Konstantin I. Popov, Alison D. Axtman

    Vydáno 2025
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  2. 2
    Development of a potent and selective chemical probe for the pleiotropic kinase CK2

    Development of a potent and selective chemical probe for the pleiotropic kinase CK2 Autor Carrow I. Wells, David H. Drewry, Julie E. Pickett, Amelie Tjaden, Andreas Krämer, Susanne Müller, Laszlo Gyenis, Daniel Menyhart, David W. Litchfield, Stefan Knapp, Alison D. Axtman

    Vydáno 2021
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  3. 3
    Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A

    Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-<i>a</i>]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A Autor Xuan Yang, Han Wee Ong, Rebekah J. Dickmander, Jeffery L. Smith, Jason W. Brown, William C. Tao, Edcon Chang, Nathaniel J. Moorman, Alison D. Axtman, Timothy M. Willson

    Vydáno 2023
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  4. 4
    Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1

    Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1 Autor Sam A. Jamieson, Zheng Ruan, Abigail E. Burgess, Jack R. Curry, Hamish D. McMillan, Jodi L. Brewster, Anita K. Dunbier, Alison D. Axtman, Natarajan Kannan, Peter D. Mace

    Vydáno 2018
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  5. 5
    Strategic Fluorination to Achieve a Potent, Selective, Metabolically-Stable, and Orally-Bioavailable Inhibitor of CSNK2.

    Strategic Fluorination to Achieve a Potent, Selective, Metabolically-Stable, and Orally-Bioavailable Inhibitor of CSNK2. Autor Han Wee Ong, Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander, Tammy M. Havener, Marcia K. Sanders, Jason W. Brown, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark T. Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson

    Vydáno 2024
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  6. 6
    Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

    Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2 Autor Han Wee Ong, Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander, Tammy M. Havener, Marcia K. Sanders, Jason W. Brown, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark T. Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson

    Vydáno 2024
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  7. 7
    More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

    More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication Autor Han Wee Ong, Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Jason W. Brown, Tammy M. Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K. Sanders, Jacob L. Capener, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark T. Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson

    Vydáno 2024
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  8. 8
    More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-<i>a</i>]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

    More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-<i>a</i>]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication Autor Han Wee Ong, Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Jason W. Brown, Tammy M. Havener, Sharon Taft-Benz, Stefanie Howell, Marcia K. Sanders, Jacob L. Capener, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark T. Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson

    Vydáno 2024
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  9. 9
    SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K

    SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K Autor Carrow I. Wells, Rafael M. Couñago, Juanita C. Limas, Tuanny L. Almeida, Jeanette Gowen Cook, David H. Drewry, Jonathan M. Elkins, O. Gileadi, Nirav Kapadia, Álvaro Lorente‐Macías, Julie E. Pickett, Alexander J. Riemen, Roberta R. Ruela-de-Sousa, Timothy M. Willson, Cunyu Zhang, William J. Zuercher, Reena Zutshi, Alison D. Axtman

    Vydáno 2019
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  10. 10
    A Chemical Probe Targeting AAK1 and BMP2K

    A Chemical Probe Targeting AAK1 and BMP2K Autor Carrow I. Wells, Rafael M. Couñago, Juanita C. Limas, Tuanny L. Almeida, Jeanette Gowen Cook, David H. Drewry, Jonathan M. Elkins, O. Gileadi, Nirav S. Kapadia, Álvaro Lorente‐Macías, Julie E. Pickett, Alexander J. Riemen, Roberta R. Ruela-de-Sousa, Timothy M. Willson, Cunyu Zhang, William J. Zuercher, Reena Zutshi, Alison D. Axtman

    Vydáno 2019
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  11. 11
    Progress Towards a Public Chemogenomic Set for Protein Kinases and a Call for Contributions

    Progress Towards a Public Chemogenomic Set for Protein Kinases and a Call for Contributions Autor David H. Drewry, Carrow I. Wells, David Andrews, Richard Angell, Hassan Al‐Ali, Alison D. Axtman, Stephen J. Capuzzi, Jonathan M. Elkins, Peter Ettmayer, Mathias Frederiksen, O. Gileadi, Nathanael S. Gray, Alice Hooper, Stefan Knapp, Stefan Laufer, Ulrich Luecking, Susanne Müller, Eugene Muratov, R. Aldrin Denny, Kumar Singh Saikatendu, Daniel K. Treiber, William J. Zuercher, Timothy M. Willson

    Vydáno 2017
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  12. 12
    Progress towards a public chemogenomic set for protein kinases and a call for contributions

    Progress towards a public chemogenomic set for protein kinases and a call for contributions Autor David H. Drewry, Carrow I. Wells, David Andrews, Richard Angell, Hassan Al‐Ali, Alison D. Axtman, Stephen J. Capuzzi, Jonathan M. Elkins, Peter Ettmayer, Mathias Frederiksen, O. Gileadi, Nathanael S. Gray, Alice Hooper, Stefan Knapp, Stefan Laufer, Ulrich Luecking, Michel Michaelides, Susanne Müller, Eugene Muratov, R. Aldrin Denny, Kumar Singh Saikatendu, Daniel K. Treiber, William J. Zuercher, Timothy M. Willson

    Vydáno 2017
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  13. 13
    AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6

    AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6 Autor Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman, Roberta R. Ruela-de-Sousa, Alex D. Rabinowitz, David M. Graham, Meagan B. Ryan, Donald Serafín, James M. Bennett, Rafael M. Couñago, David H. Drewry, Jonathan M. Elkins, C. Gileadi, O. Gileadi, Paulo H. Godoi, Nirav Kapadia, Susanne Müller, André da Silva Santiago, F.J. Sorrell, Carrow I. Wells, Oleg Fedorov, Timothy M. Willson, William J. Zuercher, Michael B. Major

    Vydáno 2018
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  14. 14
    WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

    WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop Autor Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman, Roberta R. Ruela-de-Sousa, Donald Serafín, Alex D. Rabinowitz, David M. Graham, Meagan B. Ryan, Tigist Y. Tamir, Yuko Nakamichi, Melissa V. Gammons, James M. Bennett, Rafael M. Couñago, David H. Drewry, Jonathan M. Elkins, C. Gileadi, O. Gileadi, Paulo H. Godoi, Nirav Kapadia, Susanne Müller, André da Silva Santiago, F.J. Sorrell, Carrow I. Wells, Oleg Fedorov, Timothy M. Willson, William J. Zuercher, Michael B. Major

    Vydáno 2019
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